Search Results - "Kipp, Benjamin"

COVID-19–Associated Nonocclusive Fibrin Microthrombi in the Heart by Bois, Melanie C., Boire, Nicholas A., Layman, Andrew J., Aubry, Marie-Christine, Alexander, Mariam P., Roden, Anja C., Hagen, Catherine E., Quinton, Reade A., Larsen, Christopher, Erben, Young, Majumdar, Ramanath, Jenkins, Sarah M., Kipp, Benjamin R., Lin, Peter T., Maleszewski, Joseph J.

“…Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) and its resultant clinical presentation, coronavirus disease 2019 (COVID-19), is an emergent cause…”
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Non-V600 BRAF Mutations Define a Clinically Distinct Molecular Subtype of Metastatic Colorectal Cancer by Jones, Jeremy C, Renfro, Lindsay A, Al-Shamsi, Humaid O, Schrock, Alexa B, Rankin, Andrew, Zhang, Ben Y, Kasi, Pashtoon M, Voss, Jesse S, Leal, Alexis D, Sun, James, Ross, Jeffrey, Ali, Siraj M, Hubbard, Joleen M, Kipp, Benjamin R, McWilliams, Robert R, Kopetz, Scott, Wolff, Robert A, Grothey, Axel

“…Purpose Molecular diagnostic testing has become an integral part of the evaluation of patients with metastatic colorectal cancer (CRC). Expanded mutational…”
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Molecular profiling of cholangiocarcinoma shows potential for targeted therapy treatment decisions by Voss, Jesse S., CT, MB, Holtegaard, Leonard M., BS, MB, Kerr, Sarah E., MD, Fritcher, Emily G. Barr, CT, MB (ASCP), Roberts, Lewis R., MB, ChB, PhD, Gores, Gregory J., MD, Zhang, Jun, MD, Highsmith, W. Edward, PhD, Halling, Kevin C., MD, PhD, Kipp, Benjamin R., PhD

“…Summary Cholangiocarcinoma is a highly lethal cancer of the biliary tract. The intrahepatic subtype of cholangiocarcinoma is increasing in incidence globally…”
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The genomic landscape of small intestine neuroendocrine tumors by Banck, Michaela S, Kanwar, Rahul, Kulkarni, Amit A, Boora, Ganesh K, Metge, Franziska, Kipp, Benjamin R, Zhang, Lizhi, Thorland, Erik C, Minn, Kay T, Tentu, Ramesh, Eckloff, Bruce W, Wieben, Eric D, Wu, Yanhong, Cunningham, Julie M, Nagorney, David M, Gilbert, Judith A, Ames, Matthew M, Beutler, Andreas S

“…Small intestine neuroendocrine tumors (SI-NETs) are the most common malignancy of the small bowel. Several clinical trials target PI3K/Akt/mTOR signaling;…”
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Molecular alterations in primary and metastatic PEComa: insights from the AACR project GENIE data set by Gagnon, Marie-France, Schoolmeester, J Kenneth, Dasari, Surendra, Kipp, Benjamin R, Cheville, John C, Gupta, Sounak

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Fibroblast growth factor receptor 2 translocations in intrahepatic cholangiocarcinoma by Graham, Rondell P., MBBS, Barr Fritcher, Emily G, Pestova, Ekaterina, PhD, Schulz, John, Sitailo, Leonid A., PhD, Vasmatzis, George, PhD, Murphy, Stephen J., PhD, McWilliams, Robert R., MD, Hart, Steven N., PhD, Halling, Kevin C., MD, PhD, Roberts, Lewis R., MB, ChB, PhD, Gores, Gregory J., MD, Couch, Fergus J., PhD, Zhang, Lizhi, MD, Borad, Mitesh J., MD, Kipp, Benjamin R., PhD

“…Summary Patients with cholangiocarcinoma often present with locally advanced or metastatic disease. There is a need for effective therapeutic strategies for…”
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Ciliated Muconodular Papillary Tumors of the Lung Can Occur in Western Patients and Show Mutations in BRAF and AKT1 by Liu, Liping, Aesif, Scott W, Kipp, Benjamin R, Voss, Jesse S, Daniel, Silver, Aubry, Marie Christine, Boland, Jennifer M

“…Ciliated muconodular papillary tumors (CMPTs) are rare peripheral lung lesions, characterized by papillary architecture and ciliated columnar cells admixed…”
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ECPPF (E2F1, CCNA2, POLE, PPP2R1A, FBXW7) stratification: Profiling high-risk subtypes of histomorphologically low-risk and treatment-insensitive endometrioid endometrial cancer by Gonzalez-Bosquet, Jesus, Weroha, S John, Bakkum-Gamez, Jamie N, Weaver, Amy L, McGree, Michaela E, Dowdy, Sean C, Famuyide, Abimbola O, Kipp, Benjamin R, Halling, Kevin C, Yadav, Siddhartha, Couch, Fergus J, Podratz, Karl C

“…In endometrial cancer, occult high-risk subtypes (rooted in histomorphologically low-risk disease) with insensitivity to adjuvant therapies impede improvements…”
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Isocitrate dehydrogenase 1 and 2 mutations in cholangiocarcinoma by Kipp, Benjamin R., PhD, Voss, Jesse S., BS, CT, MB(ASCP), Kerr, Sarah E., MD, Barr Fritcher, Emily G., BA, CT, MB(ASCP), Graham, Rondell P., MBBS, Zhang, Lizhi, MD, Highsmith, W. Edward, PhD, Zhang, Jun, MD, Roberts, Lewis R., MB, ChB, PhD, Gores, Gregory J., MD, Halling, Kevin C., MD, PhD

“…Summary Somatic mutations in isocitrate dehydrogenase 1 and 2 genes are common in gliomas and help stratify patients with brain cancer into histologic and…”
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Identification of independent primary tumors and intrapulmonary metastases using DNA rearrangements in non-small-cell lung cancer by Murphy, Stephen J, Aubry, Marie-Christine, Harris, Faye R, Halling, Geoffrey C, Johnson, Sarah H, Terra, Simone, Drucker, Travis M, Asiedu, Michael K, Kipp, Benjamin R, Yi, Eunhee S, Peikert, Tobias, Yang, Ping, Vasmatzis, George, Wigle, Dennis A

“…Distinguishing independent primary tumors from intrapulmonary metastases in non-small-cell carcinoma remains a clinical dilemma with significant clinical…”
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An Optimized Set of Fluorescence In Situ Hybridization Probes for Detection of Pancreatobiliary Tract Cancer in Cytology Brush Samples by Barr Fritcher, Emily G, Voss, Jesse S, Brankley, Shannon M, Campion, Michael B, Jenkins, Sarah M, Keeney, Matthew E, Henry, Michael R, Kerr, Sarah M, Chaiteerakij, Roongruedee, Pestova, Ekaterina V, Clayton, Amy C, Zhang, Jun, Roberts, Lewis R, Gores, Gregory J, Halling, Kevin C, Kipp, Benjamin R

“…Background & Aims Pancreatobiliary cancer is detected by fluorescence in situ hybridization (FISH) of pancreatobiliary brush samples with UroVysion probes,…”
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A reverse-transcription droplet digital PCR assay to detect and quantify SARS-CoV-2 RNA in upper respiratory tract specimens by Milosevic, Dragana, Moyer, Ann M., Majumdar, Ramanath, Kipp, Benjamin R., Yao, Joseph D.

“…•Development of a reverse-transcription droplet digital PCR (RT-ddPCR) assay for quantification of SARS-CoV-2 RNA in clinical nasopharyngeal and oropharyngeal…”
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Incidence of succinate dehydrogenase and fumarate hydratase–deficient renal cell carcinoma based on immunohistochemical screening with SDHA/SDHB and FH/2SC by Gupta, Sounak, Swanson, Amy A., Chen, Ying-Bei, Lopez, Tilcia, Milosevic, Dragana, Kipp, Benjamin R., Leibovich, Bradley C., Thompson, R. Houston, Herrera-Hernandez, Loren, Cheville, John C., Jimenez, Rafael E.

“…Mutations of the succinate dehydrogenase (SDHX) enzyme subunits commonly lead to a loss of function of the holoenzyme complex, and germline SDHX mutations lead…”
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Differentiating Germline vs Somatic Variants in Cancer Tissue: Are Large-Panel Genetic Tests Helping or Hurting the Cancer Patient? by Kipp, Benjamin R

“…[...]comprehensive genetic testing using NGS gene panels is becoming more common to help clinicians select appropriate therapies. Laboratories also need to…”
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Molecular characterization of pulmonary sarcomatoid carcinoma: analysis of 33 cases by Terra, Simone BSP, Jang, Jin S, Bi, Lintao, Kipp, Benjamin R, Jen, Jin, Yi, Eunhee S, Boland, Jennifer M

“…Several targetable genetic alterations have been found in lung cancer, predominantly in adenocarcinomas, which have led to important therapeutic advancements…”
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Association of a novel endometrial cancer biomarker panel with prognostic risk, platinum insensitivity, and targetable therapeutic options by Bosquet, Jesus Gonzalez, Zhang, Qing, Cliby, William A, Bakkum-Gamez, Jamie N, Cen, Ling, Dowdy, Sean C, Sherman, Mark E, Weroha, S John, Clayton, Amy C, Kipp, Benjamin R, Halling, Kevin C, Couch, Fergus J, Podratz, Karl C

“…During the past decade, the age-adjusted mortality rate for endometrial cancer (EC) increased 1.9% annually with TP53 mutant (TP53-mu) EC disproportionally…”
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Targeted deep sequencing of mucinous ovarian tumors reveals multiple overlapping RAS-pathway activating mutations in borderline and cancerous neoplasms by Mackenzie, Robertson, Kommoss, Stefan, Winterhoff, Boris J, Kipp, Benjamin R, Garcia, Joaquin J, Voss, Jesse, Halling, Kevin, Karnezis, Anthony, Senz, Janine, Yang, Winnie, Prigge, Elena-Sophie, Reuschenbach, Miriam, Doeberitz, Magnus Von Knebel, Gilks, Blake C, Huntsman, David G, Bakkum-Gamez, Jamie, McAlpine, Jessica N, Anglesio, Michael S

“…Mucinous ovarian tumors represent a distinct histotype of epithelial ovarian cancer. The rarest (2-4 % of ovarian carcinomas) of the five major histotypes,…”
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Biology and grading of pleomorphic xanthoastrocytoma—what have we learned about it? by Vaubel, Rachael, Zschernack, Valentina, Tran, Quynh T., Jenkins, Sarah, Caron, Alissa, Milosevic, Dragana, Smadbeck, James, Vasmatzis, George, Kandels, Daniela, Gnekow, Astrid, Kramm, Christof, Jenkins, Robert, Kipp, Benjamin R., Rodriguez, Fausto J., Orr, Brent A., Pietsch, Torsten, Giannini, Caterina

“…Pleomorphic xanthoastrocytoma (PXA) is a rare astrocytoma predominantly affecting children and young adults. We performed comprehensive genomic…”
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Clinicopathologic and Molecular Characteristics of Resected Thoracic Mass Lesions in the Pediatric Population: A 25-Year Institutional Experience From a Tertiary Care Center by Villalba, Julian A, Terra, Simone Bsp, Pitel, Beth, Knight, Shannon M, Kipp, Benjamin R, Boland, Jennifer M

“…Primary thoracic neoplasms are rare in children, whereas nonneoplastic mass lesions or cysts and metastases are more common, and there is a relative paucity of…”
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KRAS Mutations in Papillary Fibroelastomas: A Study of 50 Cases With Etiologic and Diagnostic Implications by Bois, Melanie C., Milosevic, Dragana, Kipp, Benjamin R., Maleszewski, Joseph J.

“…Papillary fibroelastoma (PFE) is an increasingly recognized cardiac tumor. Despite its prevalence, controversy exists as to whether it represents a reactive or…”
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