Search Results - "Kipke, D R"

Spatial steering of deep brain stimulation volumes using a novel lead design by Martens, H.C.F, Toader, E, Decré, M.M.J, Anderson, D.J, Vetter, R, Kipke, D.R, Baker, Kenneth B, Johnson, Matthew D, Vitek, Jerrold L

“…Abstract Objective To investigate steering the volume of activated tissue ( VTA ) with deep brain stimulation (DBS) using a novel high spatial-resolution lead…”
Get full text

The Electrocorticogram Signal Can Be Modulated With Deep Brain Stimulation of the Subthalamic Nucleus in the Hemiparkinsonian Rat by Lehmkuhle, M. J, Bhangoo, S. S, Kipke, D. R

“…1 Department of Biomedical Engineering, University of Michigan, Ann Arbor; and 2 Neurosurgery Department, Henry Ford Hospital, Detroit, Michigan Submitted 1…”
Get full text

Estimation of electrode location in a rat motor cortex by laminar analysis of electrophysiology and intracortical electrical stimulation by Yazdan-Shahmorad, A, Lehmkuhle, M J, Gage, G J, Marzullo, T C, Parikh, H, Miriani, R M, Kipke, D R

“…While the development of microelectrode arrays has enabled access to disparate regions of a cortex for neurorehabilitation, neuroprosthetic and basic…”
Get more information

In vivo evaluation of a neural stem cell-seeded prosthesis by Purcell, E K, Seymour, J P, Yandamuri, S, Kipke, D R

“…Neural prosthetics capable of recording or stimulating neuronal activity may restore function for patients with motor and sensory deficits resulting from…”
Get more information

Wireless implantable microsystems: high-density electronic interfaces to the nervous system by WISE, K.D., ANDERSON, D.J., HETKE, J.F., KIPKE, D.R., NAJAFI, K.

“…This paper describes the development of a high-density electronic interface to the central nervous system. Silicon micromachined electrode arrays now permit…”
Get full text

Reduction of neurovascular damage resulting from microelectrode insertion into the cerebral cortex using in vivo two-photon mapping by Kozai, T D Y, Marzullo, T C, Hooi, F, Langhals, N B, Majewska, A K, Brown, E B, Kipke, D R

“…Penetrating neural probe technologies allow investigators to record electrical signals in the brain. The implantation of probes causes acute tissue damage,…”
Get more information

The insulation performance of reactive parylene films in implantable electronic devices by Seymour, John P, Elkasabi, Yaseen M, Chen, Hsien-Yeh, Lahann, Joerg, Kipke, Daryl R

“…Abstract Parylene-C (poly-chloro-p-xylylene) is an appropriate material for use in an implantable, microfabricated device. It is hydrophobic, conformally…”
Get full text

Chronic neural recording using silicon-substrate microelectrode arrays implanted in cerebral cortex by Vetter, R.J., Williams, J.C., Hetke, J.F., Nunamaker, E.A., Kipke, D.R.

“…An important aspect of the development of cortical prostheses is the enhancement of suitable implantable microelectrode arrays for chronic neural recording…”
Get full text

Silicon-substrate intracortical microelectrode arrays for long-term recording of neuronal spike activity in cerebral cortex by Kipke, D.R., Vetter, R.J., Williams, J.C., Hetke, J.F.

“…This study investigated the use of planar, silicon-substrate microelectrodes for chronic unit recording in the cerebral cortex. The 16-channel microelectrodes…”
Get full text

Unilateral neuromodulation of the ventromedial hypothalamus of the rat through deep brain stimulation by Lehmkuhle, M J, Mayes, S M, Kipke, D R

“…This study offers evidence that long-term deep brain stimulation of the ventromedial hypothalamus (VMH) can alter weight gain in mammals without affecting…”
Get more information

Flexible polyimide-based intracortical electrode arrays with bioactive capability by Rousche, P.J., Pellinen, D.S., Pivin, D.P., Williams, J.C., Vetter, R.J., Kipke, D.R.

“…The promise of advanced neuroprosthetic systems to significantly improve the quality of life for a segment of the deaf, blind, or paralyzed population hinges…”
Get full text

Voltage pulses change neural interface properties and improve unit recordings with chronically implanted microelectrodes by Otto, K.J., Johnson, M.D., Kipke, D.R.

“…Current neuroprosthetic systems based on electrophysiological recording have an extended, yet finite working lifetime. Some posited lifetime-extension…”
Get full text

Repeated voltage biasing improves unit recordings by reducing resistive tissue impedances by Johnson, M.D., Otto, K.J., Kipke, D.R.

“…Reactive tissue encapsulation of chronically implanted microelectrode probes can preclude long-term recording of extracellular action potentials. We…”
Get full text

Long-term neural recording characteristics of wire microelectrode arrays implanted in cerebral cortex by Williams, Justin C, Rennaker, Robert L, Kipke, Daryl R

“…This paper describes a detailed protocol for obtaining chronic, multi-site unit recordings in cerebral cortex of awake animals for periods of three months or…”
Get full text

Characterization of implantable microfabricated fluid delivery devices by Rathnasingham, R., Kipke, D.R., Bledsoe, S.C., McLaren, J.D.

“…The formal characterization of the performance of microfluidic delivery devices is crucial for reliable in vivo application. A comprehensive laboratory…”
Get full text

Shared-stimulus driving and connectivity in groups of neurons in the dorsal cochlear nucleus by Kipke, D R, Clopton, B M, Anderson, D J

“…Extracellular spike discharges were recorded from ensembles of up to five neurons simultaneously in the DCN of guinea pig using solid-state, thin-film,…”
Get more information

Mechanisms of the cochlear nucleus octopus cell's onset response: synaptic effectiveness and threshold by Levy, K L, Kipke, D R

“…Octopus cells are one of the principal cell types in the mammalian posteroventral cochlear nucleus. These cells respond to the onset of a toneburst with a…”
Get full text

Neural probe design for reduced tissue encapsulation in CNS by Seymour, John P, Kipke, Daryl R

“…Abstract This study investigated relationships between a microscale neural probe's size and shape and its chronic reactive tissue response. Parylene-based…”
Get full text

Implantable neural probe systems for cortical neuroprostheses by Kipke, D R

“…Advanced microfabrication processes, biomaterials, and systems technologies are enabling progressively more sophisticated devices to interface with the brain…”
Get full text

Calcium alginate gel: A biocompatible and mechanically stable polymer for endovascular embolization by Becker, Timothy A., Kipke, Daryl R., Brandon, Tedd

“…The development and optimization of calcium alginate for potential use in endovascular occlusion was investigated by testing its in vitro and in vivo…”
Get full text