Search Results - "Kioussis, D."

Tnfaip8 is an essential gene for the regulation of glucocorticoid-mediated apoptosis of thymocytes by Woodward, M J, de Boer, J, Heidorn, S, Hubank, M, Kioussis, D, Williams, O, Brady, H J M

“…Glucocorticoids have significant immunoregulatory actions on thymocytes and T cells and act by binding and activating cytosolic glucocorticoid receptors, which…”
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The homeobox gene Hex is required in definitive endodermal tissues for normal forebrain, liver and thyroid formation by Martinez Barbera, J P, Clements, M, Thomas, P, Rodriguez, T, Meloy, D, Kioussis, D, Beddington, R S

“…The homeobox gene Hex is expressed in the anterior visceral endoderm (AVE) and rostral definitive endoderm of early mouse embryos. Later, Hex transcripts are…”
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The European dimension for the mouse genome mutagenesis program by Auwerx, Johan, Avner, Phil, Baldock, Richard, Ballabio, Andrea, Balling, Rudi, Barbacid, Mariano, Berns, Anton, Bradley, Allan, Brown, Steve, Carmeliet, Peter, Chambon, Pierre, Cox, Roger, Davidson, Duncan, Davies, Kay, Duboule, Denis, Forejt, Jiri, Granucci, Francesca, Hastie, Nick, de Angelis, Martin Hrabé, Jackson, Ian, Kioussis, Dimitris, Kollias, George, Lathrop, Mark, Lendahl, Urban, Malumbres, Marcos, von Melchner, Harald, Müller, Werner, Partanen, Juha, Ricciardi-Castagnoli, Paola, Rigby, Peter, Rosen, Barry, Rosenthal, Nadia, Skarnes, Bill, Stewart, A Francis, Thornton, Janet, Tocchini-Valentini, Glauco, Wagner, Erwin, Wahli, Walter, Wurst, Wolfgang

“…The European Mouse Mutagenesis Consortium is the European initiative contributing to the international effort on functional annotation of the mouse genome. Its…”
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Characterization of network morphology in anion binding hydrogels used for wastewater remediation by Kioussis, Dimitri R., Kofinas, Peter

“…This work reports on morphological features of hydrogels, which have been used for the ultimate removal and recovery of nutrient and toxic anions from…”
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Position effect variegation and imprinting of transgenes in lymphocytes by Williams, Adam, Harker, Nicola, Ktistaki, Eleni, Veiga-Fernandes, Henrique, Roderick, Kathleen, Tolaini, Mauro, Norton, Trisha, Williams, Keith, Kioussis, Dimitris

“…Sequences proximal to transgene integration sites are able to deregulate transgene expression resulting in complex position effect phenotypes. In addition,…”
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Transgenic mice expressing human tumour necrosis factor: a predictive genetic model of arthritis by Keffer, J., Probert, L., Cazlaris, H., Georgopoulos, S., Kaslaris, E., Kioussis, D., Kollias, G.

“…We have generated transgenic mouse lines carrying and expressing wild‐type and 3′‐modified human tumour necrosis factor (hTNF‐alpha, cachectin) transgenes. We…”
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TEL-AML1 preleukemic activity requires the DNA binding domain of AML1 and the dimerization and corepressor binding domains of TEL by MORROW, M, SAMANTA, A, KIOUSSIS, D, BRADY, H. J. M, WILLIAMS, O

“…The t(12;21)(p13;q22) translocation generates the TEL-AML1 (TEL, translocation-Ets-leukemia; AML1, acute myeloid leukemia-1) (ETV6-RUNX1) fusion product and is…”
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The AXH module: an independently folded domain common to ataxin-1 and HBP1 by de Chiara, C., Giannini, C., Adinolfi, S., de Boer, J., Guida, S., Ramos, A., Jodice, C., Kioussis, D., Pastore, A.

“…Ataxin-1 (ATX1), a human protein responsible for spinocerebellar ataxia type 1 in humans, shares a region of homology, named AXH module, with the apparently…”
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Locus Control Region Function and Heterochromatin-Induced Position Effect Variegation by Festenstein, Richard, Tolaini, Mauro, Corbella, Paola, Mamalaki, Clio, Parrington, Jenny, Fox, Margaret, Miliou, Antigoni, Jones, Margaret, Kioussis, Dimitris

“…Human CD2 locus control region (LCR) sequences are shown here to be essential for establishing an open chromatin configuration. Transgenic mice carrying an…”
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Direct Derivation of Conditionally Immortal Cell Lines from an H-2Kb- tsA58 Transgenic Mouse by Jat, Parmjit S., Noble, Mark D., Ataliotis, Paris, Tanaka, Yujiro, Yannoutsos, Nikos, Larsen, Lena, Kioussis, Dimitris

“…Studies on cell lines have greatly improved our understanding of many important biological questions. Generation of cell lines is facilitated by the…”
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Characterization of anion diffusion in polymer hydrogels used for wastewater remediation by Kioussis, Dimitri R., Kofinas, Peter

“…Ion exchange systems for the removal of nutrient pollutants, even at extremely low concentrations, from wastewater effluents are a major environmental need…”
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Competitive and cost effective copper/low-k interconnect (BEOL) for 28 nm CMOS technologies by AUGUR, R, CHILD, C, QUON, R, KIM, B, SHENG, H, HIROOKA, S, GUPTA, R, THOMAS, A, SINGH, S. M, FANG, Q, SCHIWON, R, HAMIEH, B, AHN, J. H, WORNYO, E, ALLEN, S, KALTALIOGLU, E, RIBES, G, ZHANG, G, FRYXELL, T, OGINO, A, SHIMADA, E, AIZAWA, H, MINDA, H, TANG, T. J, KIM, S. O, OKI, T, FUJII, K, PALLACHALIL, M, TAKEWAKI, T, HU, C. K, SUNDLOF, B, PERMANA, D, BOLOM, T, ENGEL, B, CLEVENGER, L, LABELLE, C, SAPP, B, NOGAMI, T, SIMON, A, SHOBHA, H, GATES, S, RYAN, E. T, BONILLA, G, DAUBENSPECK, T, SHAW, T, KIOUSSIS, D, OSBORNE, G, GRILL, A, EDELSTEIN, D, RESTAINO, D, MOLIS, S, SPOONER, T, FERREIRA, P, BIERY, G, SAMPSON, R, MASUDA, H, SRIVASTAVA, R, ODA, Y, OGUMA, H

“…A cost effective 28 nm CMOS Interconnect technology is presented for 28 nm node high performance and low power applications. Full entitlement of ultra low-k…”
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Reactive Phosphorus Removal from Aquaculture and Poultry Productions Systems Using Polymeric Hydrogels by Kofinas, Peter, Kioussis, Dimitri R

“…This work reports on the features of a sorption processes for the ultimate removal and recovery of reactive phosphorus from aquaculture and poultry production…”
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The strength of BEOL structures fabricated using low K materials and its impact on CPI failures by Shaw, T. M., Liu, X.-H, Misra, E., Questad, D., Bonilla, G., Wassick, T., Lamorey, M., Shobha, H., Osborne, G., Kioussis, D., Wright, J., Bisson, R., Paquin, I., Bouchard, S. S., Tetreault, S., Stone, D., Muzzy, C., Sundlof, B., Daubenspeck, T.

“…The paper examines the factors that affect the formation of delaminations under C4 joints during chip joining. Through multiscale finite element modeling and…”
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Embryonic expression and cloning of the murine GATA-3 gene by GEORGE, K. M, LEONARD, M. W, ROTH, M. E, LIEUW, K. H, KIOUSSIS, D, GROSVELD, F, ENGEL, J. D

“…We describe the embryonic expression pattern as well as the cloning and initial transcriptional regulatory analysis of the murine (m) GATA-3 gene. In situ…”
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Thymic Depletion and Peripheral Activation of Class I Major Histocompatibility Complex-Restricted T Cells by Soluble Peptide in T-Cell Receptor Transgenic Mice by Mamalaki, Clio, Norton, Trisha, Tanaka, Yujiro, Townsend, Alain R., Chandler, Phillip, Simpson, Elizabeth, Kioussis, Dimitris

“…Injection of mice transgenic for a class I major histocompatibility complex-restricted T-cell receptor with a soluble peptide antigen from influenza virus…”
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Immune and Nervous Systems: More Than Just a Superficial Similarity? by Kioussis, Dimitris, Pachnis, Vassilis

“…Strong evidence is emerging that the nervous and immune systems share mechanisms of gene regulation, signaling, cell communication, and supracellular…”
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Stochastic Component to Development of Class I Major Histocompatibility Complex-Specific T Cells by Itano, Andrea, Kioussis, Dimitris, Robey, Ellen

“…The mechanism by which an initially uncommitted cell chooses between alternative fates is a central issue in developmental biology. In the mammalian thymus,…”
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Random activation of a transgene under the control of a hybrid hCD2 locus control region/Ig enhancer regulatory element by Elliott, J.I., Festenstein, R., Tolaini, M., Kioussis, D.

“…Locus control regions such as those of human CD2 and beta‐globin differ from classical enhancers in that, whereas the former confer high level, copy‐dependent,…”
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T-cell lymphomas in v-Myb transgenic mice by Badiani, P A, Kioussis, D, Swirsky, D M, Lampert, I A, Weston, K

“…v-Myb, the transforming protein of avian myeloblastosis virus, causes acute myeloid leukemia in chickens. Similarly, truncation and rearrangement of the c-myb…”
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