Search Results - "Kinouchi, Makoto"

Association between being breastfed in infancy and adult colorectal cancer risk among Japanese men and women by Minami, Yuko, Kanemura, Seiki, Kusaka, Jun, Kinouchi, Makoto, Suzuki, Shinichi, Iwasashi, Hajime, Nishino, Yoshikazu, Kakugawa, Yoichiro, Miura, Koh

“…It has been postulated that being breastfed in infancy affects not only health status in childhood but also disease risk in adulthood. To investigate the…”
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Associations of cigarette smoking, alcohol drinking and body mass index with survival after colorectal cancer diagnosis by anatomic subsite: a prospective patient cohort study in Japan by Minami, Yuko, Kanemura, Seiki, Kusaka, Jun, Kinouchi, Makoto, Suzuki, Shinichi, Nishino, Yoshikazu, Miura, Koh

“…Abstract Background Cigarette smoking, alcohol drinking and obesity are known to be risk factors for colorectal cancer. These factors may affect survival after…”
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Determination of the origin of oral squamous cell carcinoma by microarray analysis: Squamous epithelium or minor salivary gland? by Kinouchi, Makoto, Izumi, Sayaka, Nakashiro, Koh‐ichi, Haruyama, Yasuo, Kobashi, Gen, Uchida, Daisuke, Hasegawa, Tomonori, Kawamata, Hitoshi

“…More than 90% of oral cancers are histopathologically squamous cell carcinomas (SCCs). According to clinical behavior and histopathological features, we…”
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5-fu metabolism in cancer and orally-administrable 5-fu drugs by Miura, Koh, Kinouchi, Makoto, Ishida, Kazuyuki, Fujibuchi, Wataru, Naitoh, Takeshi, Ogawa, Hitoshi, Ando, Toshinori, Yazaki, Nobuki, Watanabe, Kazuhiro, Haneda, Sho, Shibata, Chikashi, Sasaki, Iwao

“…5-Fluorouracil (5-FU) is a key anticancer drug that for its broad antitumor activity, as well as for its synergism with other anticancer drugs, has been used…”
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Effect of a novel orally bioavailable CXCR4 inhibitor, AMD070, on the metastasis of oral cancer cells by Uchida, Daisuke, Kuribayashi, Nobuyuki, Kinouchi, Makoto, Sawatani, Yuta, Shimura, Michiko, Mori, Toshimitsu, Hasegawa, Tomonori, Miyamoto, Youji, Kawamata, Hitoshi

“…We have previously demonstrated that the stromal cell‑derived factor (SDF‑1)/CXCR4 system is involved in the metastasis of head and neck cancer. Additionally,…”
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Involvement of miR-518c-5p to growth and metastasis in oral cancer by Kinouchi, Makoto, Uchida, Daisuke, Kuribayashi, Nobuyuki, Tamatani, Tetsuya, Nagai, Hirokazu, Miyamoto, Youji

“…We have previously demonstrated that a stromal cell-derived factor-1 (SDF-1; CXCL12)/CXCR4 system is involved in the establishment of metastasis in oral…”
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Down‐regulation of cIAP2 enhances 5‐FU sensitivity through the apoptotic pathway in human colon cancer cells by Karasawa, Hideaki, Miura, Koh, Fujibuchi, Wataru, Ishida, Kazuyuki, Kaneko, Naoyuki, Kinouchi, Makoto, Okabe, Mitsunori, Ando, Toshinori, Murata, Yukio, Sasaki, Hiroyuki, Takami, Kazuhiro, Yamamura, Akihiro, Shibata, Chikashi, Sasaki, Iwao

“…Currently 5‐fluorouracil (5‐FU) plays a central role in the chemotherapeutic regimens for colorectal cancers and thus it is important to understand the…”
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Informatics for unveiling hidden genome signatures by Abe, Takashi, Kanaya, Shigehiko, Kinouchi, Makoto, Ichiba, Yuta, Kozuki, Tokio, Ikemura, Toshimichi

“…With the increasing amount of available genome sequences, novel tools are needed for comprehensive analysis of species-specific sequence characteristics for a…”
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Expression and function of CXCR4 in human salivary gland cancers by Uchida, Daisuke, Kuribayashi, Nobuyuki, Kinouchi, Makoto, Ohe, Go, Tamatani, Tetsuya, Nagai, Hirokazu, Miyamoto, Youji

“…Salivary gland cancers (SGCs) frequently metastasize to cervical lymph nodes and distant organs. Currently, the mechanisms responsible for the metastatic…”
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The preclinical development of regorafenib for the treatment of colorectal cancer by Miura, Koh, Satoh, Masayuki, Kinouchi, Makoto, Yamamoto, Kuniharu, Hasegawa, Yasuhiro, Philchenkov, Alex, Kakugawa, Yoichiro, Fujiya, Tsuneaki

“…The RAS-RAF-MEK-ERK pathway is one of the best characterized kinase cascades. During the exploration of small molecules that inhibit RAF1 kinase, regorafenib…”
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The role of metabotropic glutamate receptor 5 on the stromal cell-derived factor-1/CXCR4 system in oral cancer by Kuribayashi, Nobuyuki, Uchida, Daisuke, Kinouchi, Makoto, Takamaru, Natsumi, Tamatani, Tetsuya, Nagai, Hirokazu, Miyamoto, Youji

“…We have demonstrated that blocking CXCR4 may be a potent anti-metastatic therapy for CXCR4-related oral cancer. However, as CXCR4 antagonists are currently in…”
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Current Status of Pylorus-Preserving Gastrectomy for the Treatment of Gastric Cancer: A Questionnaire Survey and Review of Literatures by Shibata, Chikashi, Saijo, Fumito, Kakyo, Masayuki, Kinouchi, Makoto, Tanaka, Naoki, Sasaki, Iwao, Aikou, Takashi

“…Purpose This study was designed to investigate the current status of pylorus-preserving gastrectomy (PPG) for the treatment of gastric cancer by sending a…”
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Orthotopic implantation mouse model and cDNA microarray analysis indicates several genes potentially involved in lymph node metastasis of colorectal cancer by Sasaki, Hiroyuki, Miura, Koh, Horii, Akira, Kaneko, Naoyuki, Fujibuchi, Wataru, Kiseleva, Larisa, Gu, Zhaodi, Murata, Yukio, Karasawa, Hideaki, Mizoi, Takayuki, Kobayashi, Terutada, Kinouchi, Makoto, Ohnuma, Shinobu, Yazaki, Nobuki, Unno, Michiaki, Sasaki, Iwao

“…In colorectal cancer (CRC) patients, metastasis to the regional lymph node (LN) is an important first step in the dissemination of cancers. To identify the…”
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The use of natural products in colorectal cancer drug discovery by Miura, Koh, Satoh, Masayuki, Kinouchi, Makoto, Yamamoto, Kuniharu, Hasegawa, Yasuhiro, Kakugawa, Yoichiro, Kawai, Masaaki, Uchimi, Kiyoshi, Aizawa, Hiroki, Ohnuma, Shinobu, Kajiwara, Taiki, Sakurai, Hiroto, Fujiya, Tsuneaki

“…Natural products (NPs) are evolutionarily designed and contain more complex and challenging structures than synthetic compounds. Since the 1980s, the…”
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Infiltration of CD40-positive tumor-associated macrophages indicates a favorable prognosis in colorectal cancer patients by Kinouchi, Makoto, Miura, Koh, Mizoi, Takayuki, Ishida, Kazuyuki, Fujibuchi, Wataru, Sasaki, Hiroyuki, Ohnuma, Shinobu, Saito, Kazuya, Katayose, Yu, Naitoh, Takeshi, Motoi, Fuyuhiko, Shiiba, Ken-ichi, Egawa, Shinichi, Shibata, Chikashi, Unno, Michiaki

“…Recently the role of tumor-associated macrophages (TAMs) on immunity has been variously discussed. We studied a series of cell surface antigens in TAMs in…”
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Criteria for the glucagon provocative test in the diagnosis of gastrinoma by Shibata, Chikashi, Kakyo, Masayuki, Kinouchi, Makoto, Tanaka, Naoki, Miura, Koh, Naitoh, Takeshi, Ogawa, Hitoshi, Motoi, Fuyuhiko, Egawa, Shinichi, Ueno, Tatsuya, Naito, Hiroo, Unno, Michiaki

“…Introduction The glucagon provocative test is useful for the diagnosis of gastrinoma. The aim of this study was to determine the criteria for the glucagon…”
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Cancer-associated splicing variants of the CDCA1 and MSMB genes expressed in cancer cell lines and surgically resected gastric cancer tissues by Ohnuma, Shinobu, MD, Miura, Koh, MD, Horii, Akira, MD, Fujibuchi, Wataru, PhD, Kaneko, Naoyuki, MD, Gotoh, Osamu, PhD, Nagasaki, Hideki, PhD, Mizoi, Takayuki, MD, Tsukamoto, Nobukazu, MD, Kobayashi, Terutada, MD, Kinouchi, Makoto, MD, Okabe, Mitsunori, MD, Sasaki, Hiroyuki, MD, Shiiba, Ken-ichi, MD, Miyagawa, Kikuo, MD, Sasaki, Iwao, MD

“…Background Alternative splicing is a molecular mechanism by which different combinations of exons can be alternatively spliced to produce different mRNA…”
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Intracolonic capsaicin stimulates colonic motility and defecation in conscious dogs by Hayashi, Keiichi, MD, Shibata, Chikashi, MD, Nagao, Munenori, MD, Sato, Manabu, MD, Kakyo, Masayuki, MD, Kinouchi, Makoto, MD, Saijo, Fumito, MD, Miura, Koh, MD, Ogawa, Hitoshi, MD, Sasaki, Iwao, MD, FACS

“…Background The aim of this study was to investigate the effects of intracolonic capsaicin on colonic motility and defecation. Methods The effects of capsaicin…”
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Tissue oxygenation in a murine SCC VII tumor after X-ray irradiation as determined by EPR spectroscopy by Fujii, Hirotada, Sakata, Koh-ichi, Katsumata, Yoshihiro, Sato, Rikiya, Kinouchi, Makoto, Someya, Masanori, Masunaga, Shin-ichiro, Hareyama, Masato, Swartz, Harold M, Hirata, Hiroshi

“…Abstract Purpose The goal of this study was to clarify the dynamics of oxygenation (partial pressure of oxygen, pO2 ) in SCC VII murine tumors in mice after…”
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Novel Phylogenetic Studies of Genomic Sequence Fragments Derived from Uncultured Microbe Mixtures in Environmental and Clinical Samples by Abe, Takashi, Sugawara, Hideaki, Kinouchi, Makoto, Kanaya, Shigehiko, Ikemura, Toshimichi

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