Search Results - "Kinoshita, Koshi"

Epilepsy‐related sudden unexpected death: targeted molecular analysis of inherited heart disease genes using next‐generation DNA sequencing by Hata, Yukiko, Yoshida, Koji, Kinoshita, Koshi, Nishida, Naoki

“…Inherited heart disease causing electric instability in the heart has been suggested to be a risk factor for sudden unexpected death in epilepsy (SUDEP). The…”
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A rapid and efficient single-cell manipulation method for screening antigen-specific antibody-secreting cells from human peripheral blood by Kinoshita, Koshi, Takahashi, Kazuo, Muraguchi, Atsushi, Kishi, Hiroyuki, Sugiyama, Toshiro, Kadowaki, Shinichi, Jin, Aishun, Ozawa, Tatsuhiko, Obata, Tsutomu, Kondo, Sachiko, Tajiri, Kazuto

“…Jin and colleagues introduce a new chip-based system for the rapid identification and isolation of single antigen-specific antibody–secreting cells from human…”
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Argyrophilic grain disease in a 46-year-old male suicide victim by Yoshida, Koji, Hata, Yukiko, Kinoshita, Koshi, Nishida, Naoki

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MicroRNA-145-5p and microRNA-320a encapsulated in endothelial microparticles contribute to the progression of vasculitis in acute Kawasaki Disease by Nakaoka, Hideyuki, Hirono, Keiichi, Yamamoto, Seiji, Takasaki, Ichiro, Takahashi, Kei, Kinoshita, Koshi, Takasaki, Asami, Nishida, Naonori, Okabe, Mako, Ce, Wang, Miyao, Nariaki, Saito, Kazuyoshi, Ibuki, Keijiro, Ozawa, Sayaka, Adachi, Yuichi, Ichida, Fukiko

“…Kawasaki Disease (KD) is an acute inflammatory disease that takes the form of systemic vasculitis. Endothelial microparticles (EMPs) have been recognized as an…”
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Postmortem Genetic Analysis Of Sudden Unexplained Death Syndrome Under 50 Years Of Age: A Next-Generation Sequencing Study by Hata, Yukiko, PhD, Kinoshita, Koshi, PhD, Mizumaki, Koichi, MD, PhD, Yamaguchi, Yoshiaki, MD, PhD, Hirono, Keiichi, MD, PhD, Ichida, Fukiko, MD, PhD, Takasaki, Asami, MD, Mori, Hisashi, PhD, Nishida, Naoki, MD, PhD

“…Abstract Background Recent studies on the genetic analysis of victims of sudden unexplained death syndrome (SUDS) have shown diagnostic potential. Previously,…”
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Lack of modulatory effect of the SCN5A R1193Q polymorphism on cardiac fast Na+ current at body temperature by Abe, Masayoshi, Kinoshita, Koshi, Matsuoka, Kenta, Nakada, Takahito, Miura, Kimiaki, Hata, Yukiko, Nishida, Naoki, Tabata, Toshihide

“…SCN5A encodes the main subunit of the NaV1.5 channel, which mediates the fast Na+ current responsible for generating cardiac action potentials. The single…”
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Edoxaban suppresses the progression of atrial fibrosis and atrial fibrillation in a canine congestive heart failure model by Tsujino, Yasushi, Sakamoto, Tamotsu, Kinoshita, Koshi, Nakatani, Yosuke, Yamaguchi, Yoshiaki, Kataoka, Naoya, Nishida, Kunihiro, Kinugawa, Koichiro

“…Coagulation factor Xa activates the protease-activated receptor 2 (PAR2) and causes tissue fibrosis; however, the effects of Xa inhibitor edoxaban on atrial…”
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MicroRNA-93 may control vascular endothelial growth factor A in circulating peripheral blood mononuclear cells in acute Kawasaki disease by Saito, Kazuyoshi, Nakaoka, Hideyuki, Takasaki, Ichiro, Hirono, Keiichi, Yamamoto, Seiji, Kinoshita, Koshi, Miyao, Nariaki, Ibuki, Keijiro, Ozawa, Sayaka, Watanabe, Kazuhiro, Bowles, Neil E., Ichida, Fukiko

“…Background: Kawasaki disease (KD) is the most common systemic vasculitis syndrome primarily affecting medium-sized arteries, particularly the coronary…”
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A functional neuron maturation device provides convenient application on microelectrode array for neural network measurement by Han, Xiaobo, Matsuda, Naoki, Ishibashi, Yuto, Odawara, Aoi, Takahashi, Sayuri, Tooi, Norie, Kinoshita, Koshi, Suzuki, Ikuro

“…Microelectrode array (MEA) systems are valuable for in vitro assessment of neurotoxicity and drug efficiency. However, several difficulties such as protracted…”
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Pseudoaneurysmal defect of mitral-aortic intervalvular fibrosa is likely to be a cerebral embolic source. An autopsy study in remote period from the stroke by Nishida, Naoki, Hata, Yukiko, Kinoshita, Koshi, Nonomura, Makoto

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An Autopsy Case of Sudden Unexpected Death of a Young Adult in a Hot Bath: Molecular Analysis Using Next-Generation DNA Sequencing by Hata, Yukiko, Kinoshita, Koshi, Nishida, Naoki

“…We report a case of sudden unexpected death of a young woman who was found in a bathtub of hot water. The autopsy concluded that all possible causes of sudden…”
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Effect of irbesartan on development of atrial fibrosis and atrial fibrillation in a canine atrial tachycardia model with left ventricular dysfunction, association with p53 by Kataoka, Naoya, Nishida, Kunihiro, Kinoshita, Koshi, Sakamoto, Tamotsu, Nakatani, Yosuke, Tsujino, Yasushi, Mizumaki, Koichi, Inoue, Hiroshi, Kinugawa, Koichiro

“…Effects of an angiotensin II receptor blocker, irbesartan (IRB), on the development of atrial fibrosis and atrial fibrillation (AF) were assessed in a canine…”
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A mutant HCN4 channel in a family with bradycardia, left bundle branch block, and left ventricular noncompaction by Yokoyama, Ryosuke, Kinoshita, Koshi, Hata, Yukiko, Abe, Masayoshi, Matsuoka, Kenta, Hirono, Keiichi, Kano, Masanobu, Nakazawa, Makoto, Ichida, Fukiko, Nishida, Naoki, Tabata, Toshihide

“…We found that a female infant presenting with left bundle branch block and left ventricular noncompaction carries uninvestigated gene mutations HCN4(G811E),…”
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The Susceptibilities of Human Ether-à-Go-Go-Related Gene Channel with the G487R Mutation to Arrhythmogenic Factors by Hisajima, Nozomi, Hata, Yukiko, Kinoshita, Koshi, Fukushima, Toshiki, Nishida, Naoki, Kano, Masanobu, Tabata, Toshihide

“…The human ether-à-go-go-related gene (hERG) channel mediates the rapid delayed rectifier potassium current (IKr) responsible for shaping the repolarization…”
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High takeoff of the left main coronary artery at autopsy after sudden unexpected death in a male by Nishida, Naoki, Hata, Yukiko, Kinoshita, Koshi

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Glycine/Serine Polymorphism at Position 38 Influences KCNE1 Subunit’s Modulatory Actions on Rapid and Slow Delayed Rectifier K+ Currents by Yamaguchi, Yoshiaki, Nishide, Kohki, Kato, Mario, Hata, Yukiko, Mizumaki, Koichi, Kinoshita, Koshi, Nonobe, Yuki, Tabata, Toshihide, Sakamoto, Tamotsu, Kataoka, Naoya, Nakatani, Yosuke, Ichida, Fukiko, Mori, Hisashi, Fukurotani, Kenkichi, Inoue, Hiroshi, Nishida, Naoki

“…Background: KCNE1 encodes a modulator of KCNH2 and KCNQ1 delayed rectifier K+ current channels. KCNE1 mutations might cause long QT syndrome (LQTS) by…”
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Sudden unexpected death owing to unilateral medial medullary infarction with early involvement of the respiratory center by Hata, Yukiko, Yoshida, Koji, Kinoshita, Koshi, Nishida, Naoki

“…Abstract A 64-year-old woman was found dead in her home. At autopsy, although relatively fresh bruises were found on her body, no lethal injury was observed in…”
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Characterization of a novel mutant KCNQ1 channel subunit lacking a large part of the C-terminal domain by Kimoto, Katsuya, Kinoshita, Koshi, Yokoyama, Tomoki, Hata, Yukiko, Komatsu, Takuto, Tsushima, Eikichi, Nishide, Kohki, Yamaguchi, Yoshiaki, Mizumaki, Koichi, Tabata, Toshihide, Inoue, Hiroshi, Nishida, Naoki, Fukurotani, Kenkichi

“…•We found a novel mutant KCNQ1 channel subunit with a massive C-terminal truncation.•The mutant subunit could not form channels with or without the wild-type…”
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Identification of amino acid residues in the Ah receptor involved in ligand binding by Goryo, Kenji, Suzuki, Ai, Carpio, Carlos A. Del, Siizaki, Kazuhiro, Kuriyama, Eisuke, Mikami, Yoshinori, Kinoshita, Koshi, Yasumoto, Ken-ichi, Rannug, Agneta, Miyamoto, Akira, Fujii-Kuriyama, Yoshiaki, Sogawa, Kazuhiro

“…The Ah receptor (AhR) is a ligand-activated transcription factor. Five amino acids as candidate amino acids necessary for ligand binding within or near the…”
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A Novel Missense Mutation Causing a G487R Substitution in the S2-S3 Loop of Human ether-à-go-go-Related Gene Channel by KINOSHITA, KOSHI, YAMAGUCHI, YOSHIAKI, NISHIDE, KOHKI, KIMOTO, KATSUYA, NONOBE, YUKI, FUJITA, AKIRA, ASANO, KENTA, TABATA, TOSHIHIDE, MORI, HISASHI, INOUE, HIROSHI, HATA, YUKIKO, FUKUROTANI, KENKICHI, NISHIDA, NAOKI

“…hERG(G487R) Channel. Introduction: Mutations of human ether‐à‐go‐go‐related gene (hERG), which encodes a cardiac K+ channel responsible for the acceleration of…”
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