Search Results - "Kinnear, Beverley F."

Interactions between Skeletal Muscle Myoblasts and their Extracellular Matrix Revealed by a Serum Free Culture System by Chaturvedi, Vishal, Dye, Danielle E, Kinnear, Beverley F, van Kuppevelt, Toin H, Grounds, Miranda D, Coombe, Deirdre R

“…Decellularisation of skeletal muscle provides a system to study the interactions of myoblasts with muscle extracellular matrix (ECM). This study describes the…”
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Fabrication and Evaluation of Electrospun Silk Fibroin/Halloysite Nanotube Biomaterials for Soft Tissue Regeneration by Mohammadzadehmoghadam, Soheila, LeGrand, Catherine F., Wong, Chee-Wai, Kinnear, Beverley F., Dong, Yu, Coombe, Deirdre R.

“…The production of nanofibrous materials for soft tissue repair that resemble extracellular matrices (ECMs) is challenging. Electrospinning uniquely produces…”
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In Vitro Expansion of Keratinocytes on Human Dermal Fibroblast-Derived Matrix Retains Their Stem-Like Characteristics by Wong, Chee-Wai, LeGrand, Catherine F., Kinnear, Beverley F., Sobota, Radoslaw M., Ramalingam, Rajkumar, Dye, Danielle E., Raghunath, Michael, Lane, E. Birgitte, Coombe, Deirdre R.

“…The long-term expansion of keratinocytes under conditions that avoid xenogeneic components (i.e. animal serum- and feeder cell-free) generally causes…”
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Interaction Between Skeletal Muscle Cells and Extracellular Matrix Proteins Using a Serum Free Culture System by Dye, Danielle E, Kinnear, Beverley F, Chaturvedi, Vishal, Coombe, Deirdre R

“…The ability to grow C2C12 myoblasts in a completely defined, serum free medium enables researchers to investigate the role of specific factors in myoblast…”
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Silk fibroin scaffolds with muscle‐like elasticity support in vitro differentiation of human skeletal muscle cells by Chaturvedi, Vishal, Naskar, Deboki, Kinnear, Beverley F., Grenik, Elizabeth, Dye, Danielle E., Grounds, Miranda D., Kundu, Subhas C., Coombe, Deirdre R.

“…Human adult skeletal muscle has a limited ability to regenerate after injury and therapeutic options for volumetric muscle loss are few. Technologies to…”
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IL-2 Intratumoral Immunotherapy Enhances CD8+ T Cells That Mediate Destruction of Tumor Cells and Tumor-Associated Vasculature: A Novel Mechanism for IL-2 by Jackaman, Connie, Bundell, Christine S, Kinnear, Beverley F, Smith, Alison M, Filion, Pierre, van Hagen, Deborah, Robinson, Bruce W. S, Nelson, Delia J

“…Therapeutic use of IL-2 can generate antitumor immunity; however, a variety of different mechanisms have been reported. We injected IL-2 intratumorally (i.t.)…”
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Tumor-Specific CD4+ T Cells Have a Major "Post-Licensing" Role in CTL Mediated Anti-Tumor Immunity by Marzo, Amanda L, Kinnear, Beverley F, Lake, Richard A, Frelinger, Jeffrey J, Collins, Edward J, Robinson, Bruce W. S, Scott, Bernadette

“…A number of tumor studies have indicated a link between CD4 help and the magnitude and persistence of CTL activity; however, the mechanisms underlying this…”
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Platelet Endothelial Cell Adhesion Molecule 1 (PECAM-1) and Its Interactions with Glycosaminoglycans: 2. Biochemical Analyses by Coombe, Deirdre R, Stevenson, Sandra M, Kinnear, Beverley F, Gandhi, Neha S, Mancera, Ricardo L, Osmond, Ronald I. W, Kett, Warren C

“…Platelet endothelial cell adhesion molecule 1 (PECAM-1) (CD31), a member of the immunoglobulin (Ig) superfamily of cell adhesion molecules with six Ig-like…”
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Quantitative Analysis of the Effect of CD16 Ligation on Human NK Cell Proliferation by Warren, Hilary S, Kinnear, Beverley F

“…CD16 (Fc gammaRIIIA), the low affinity receptor for IgG, is expressed on the majority of human peripheral blood NK cells. Ligation of CD16 with mAb or immune…”
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Proliferation of alloreactive human natural killer cells independent of specific allogeneic stimulation by Warren, H S, Kinnear, B F, Witt, C S, Christiansen, F T

“…This study establishes that natural killer (NK) cells cytolytic for B-lymphoblastoid cell lines (B-LCL) expressing NK-defined alloantigens can be stimulated to…”
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Avidin is a heparin-binding protein. Affinity, specificity and structural analysis by Kett, Warren C, Osmond, Ronald I.W, Moe, Lily, Skett, Spencer E, Kinnear, Beverley F, Coombe, Deirdre R

“…The specificity, affinity and stoichiometry of the interaction between avidin and glycosaminoglycans (GAGs) have been investigated using heparin-coated…”
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Molecular associations involving CD 16, CD45 and ζ, and γ chains on human natural killer cells by ALTIN, JOSEPH G., PAGLER, ELOISA B., KINNEAR, BEVERLEY F., WARREN, HILARY S.

“…Summary ζ (CD3‐ζ) and γ (FcεRIγ) chains associate with CD 16. the low affinity receptor for IgG (FcλRIII) on human NK cells and are essential for the cell…”
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Silk fibroin scaffolds with muscle-like elasticity support in vitro differentiation of human skeletal muscle cells: Skeletal muscle differentiation on silk fibroin scaffolds by Chaturvedi, Vishal, Naskar, Deboki, Kinnear, Beverley F., Grenik, Elizabeth, Dye, Danielle E., Grounds, Miranda D., Kundu, Subhas C., Coombe, Deirdre R.

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Cover Image, Volume 11, Issue 11 by Chaturvedi, Vishal, Naskar, Deboki, Kinnear, Beverley F., Grenik, Elizabeth, Dye, Danielle E., Grounds, Miranda D., Kundu, Subhas C., Coombe, Deirdre R.

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Distinct granzyme expression in human CD3- CD56+ large granular- and CD3- CD56+ small high density-lymphocytes displaying non-MHC-restricted cytolytic activity by Smyth, M J, Browne, K A, Kinnear, B F, Trapani, J A, Warren, H S

“…Cultured natural killer (NK) cells derived from CD3- CD56+ high-density small lymphocytes (HDLs) exhibit similar morphology and high levels of non-major…”
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Platelet Endothelial Cell Adhesion Molecule 1 (PECAM-1) and Its Interactions with Glycosaminoglycans: 2. Biochemical Analyses super([dagger]) by Gandhi, Neha S, Kinnear, Beverley F, Stevenson, Sandra M, Osmond, Ronald IW, Kett, Warren C, Mancera, Ricardo L, Coombe, Deirdre R

“…Platelet endothelial cell adhesion molecule 1 (PECAM-1) (CD31), a member of the immunoglobulin (Ig) superfamily of cell adhesion molecules with six Ig-like…”
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Production of IL-5 by human NK cells and regulation of IL-5 secretion by IL-4, IL-10, and IL-12 by Warren, HS, Kinnear, BF, Phillips, JH, Lanier, LL

“…Human NK cells produce IFN-gamma, TNF-alpha, and granulocyte macrophage-CSF when stimulated with susceptible target cells or through the CD16 and CD94 cell…”
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Analysis of the costimulatory role of IL-2 and IL-15 in initiating proliferation of resting (CD56dim) human NK cells by Warren, HS, Kinnear, BF, Kastelein, RL, Lanier, LL

“…IL-15 is a newly described cytokine produced by monocytes and other non-T cells that utilizes the IL-2R beta- and common gamma-chains, thereby stimulating many…”
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A carbohydrate structure associated with CD15 (Lewis x) on myeloid cells is a novel ligand for human CD2 by Warren, HS, Altin, JG, Waldron, JC, Kinnear, BF, Parish, CR

“…The T cell and NK cell adhesion molecule CD2 interacts with different ligands, viz, CD58, CD48, and CD59. Using a fluorescent multimeric construct of rCD2, we…”
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Human natural killer (NK) cells: requirements for cell proliferation and expansion of phenotypically novel subpopulations by Warren, H S, Kinnear, B F, Skipsey, L J

“…Previous studies established that the high density (resting) natural killer (NK) cell subset (R-NK) of peripheral blood NK cells is unresponsive to…”
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