Search Results - "Kinkel, R. Philip"

Quantitative Oxygen Extraction Fraction from 7-Tesla MRI Phase: Reproducibility and Application in Multiple Sclerosis by Fan, Audrey P, Govindarajan, Sindhuja T, Kinkel, R Philip, Madigan, Nancy K, Nielsen, A Scott, Benner, Thomas, Tinelli, Emanuele, Rosen, Bruce R, Adalsteinsson, Elfar, Mainero, Caterina

“…Quantitative oxygen extraction fraction (OEF) in cortical veins was studied in patients with multiple sclerosis (MS) and healthy subjects via magnetic…”
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Internet portal use in an academic multiple sclerosis center by Nielsen, A Scott, Halamka, John D, Kinkel, R Philip

“…To evaluate the use of a secure internet portal in an academic Multiple Sclerosis (MS) Center. Retrospective case-control chart review of 240 patients during…”
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Spontaneous regression of primary autoreactivity during chronic progression of experimental autoimmune encephalomyelitis and multiple sclerosis by Tuohy, V K, Yu, M, Yin, L, Kawczak, J A, Kinkel, R P

“…Experimental autoimmune encephalomyelitis (EAE) is a widely used animal model for multiple sclerosis (MS). EAE is typically initiated by CD4(+) T helper cell…”
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Focal cortical lesion detection in multiple sclerosis: 3 tesla DIR versus 7 tesla FLASH-T2 by Nielsen, A. Scott, Kinkel, R. Philip, Tinelli, Emanuele, Benner, Thomas, Cohen-Adad, Julien, Mainero, Caterina

“…Purpose: To evaluate the inter‐rater agreement of cortical lesion detection using 7 Tesla (T) FLASH‐T2* and 3T DIR sequences. Materials and Methods: Twenty‐six…”
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Asymptomatic Reactivation of JC Virus in Patients Treated with Natalizumab by Chen, Yiping, Bord, Evelyn, Tompkins, Troy, Miller, Janice, Tan, Chen S, Kinkel, R. Philip, Stein, Marion C, Viscidi, Raphael P, Ngo, Long H, Koralnik, Igor J

“…Progressive multifocal leukoencephalopathy (PML) is a rare complication of natalizumab treatment and is caused by the JC virus. In this study of 19 patients…”
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Patterns of mobility aid use among working-age persons with multiple sclerosis living in the community in the United States by Iezzoni, Lisa I., M.D., M.Sc, Rao, Sowmya R., Ph.D, Kinkel, R. Philip, M.D

“…Abstract Background Difficulty walking is the most visible sign of disability among persons with multiple sclerosis (MS). However, little is known about…”
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No Evidence of Disease Activity in Multiple Sclerosis by Sloane, Jacob A, Mainero, Caterina, Kinkel, R Philip

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JC virus reactivation during prolonged natalizumab monotherapy for multiple sclerosis by Chalkias, Spyridon, Dang, Xin, Bord, Evelyn, Stein, Marion C., Kinkel, R. Philip, Sloane, Jacob A., Donnelly, Maureen, Ionete, Carolina, Houtchens, Maria K., Buckle, Guy J., Batson, Stephanie, Koralnik, Igor J.

“…Objective To determine the prevalence of JC virus (JCV) reactivation and JCV‐specific cellular immune response during prolonged natalizumab treatment for…”
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Immune reconstitution inflammatory syndrome in patients with multiple sclerosis following cessation of natalizumab therapy by Miravalle, Augusto, Jensen, Rikke, Kinkel, R Philip

“…To assess clinical consequences of temporary natalizumab dosage suspension. Prospective cohort study. Multiple sclerosis (MS) center at an academic medical…”
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Disease-related determinants of quality of life 10 years after clinically isolated syndrome by Kinkel, R Philip, Laforet, Genevieve, You, Xiaojun

“…The main clinical determinants of quality of life (QOL) 5 years after clinically isolated syndrome (CIS) are Expanded Disability Status Scale (EDSS) score and…”
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Maximally tolerated versus minimally effective dose: the case of rituximab in multiple sclerosis by Nielsen, A Scott, Miravalle, Augusto, Langer-Gould, Annette, Cooper, Joanna, Edwards, Keith R, Kinkel, R Philip

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Use and cost of disease-modifying therapies by Sonya Slifka Study participants: has anything really changed since 2000 and 2009? by Minden, Sarah L, Kinkel, R Philip, Machado, Helene T, Levin, Jonathan S, Rosenthal, Meredith B, Iezzoni, Lisa I

“…Background Disease-modifying therapies benefit individuals with relapsing forms of multiple sclerosis, but their utility remains unclear for those without…”
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Experiences acquiring and using mobility aids among working-age persons with multiple sclerosis living in communities in the United States by Iezzoni, Lisa I, Rao, Sowmya R, Kinkel, R Philip

“…To examine patterns of mobility aid ownership and use among working-age United States residents with multiple sclerosis. A 30-min telephone survey in mid-2007…”
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Asymptomatic Reactivation of JC Virus in Patients Treated with Natalizumab by Gorelik, Leonid, Goelz, Susan, Sandrock, Alfred W

“…To the Editor: Chen and colleagues (Sept. 10 issue) 1 describe an increased prevalence of JC virus DNA in 19 patients with multiple sclerosis after 12 to 18…”
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Discrepant findings in immune responses to JC virus in patients receiving natalizumab by Tan, Chen S, Chen, Yiping, Viscidi, Raphael P, Kinkel, R Philip, Stein, Marion C, Koralnik, Igor J

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Anti-Tumor Necrosis Factor Alpha-Associated Multiple Sclerosis by Titelbaum, David S, Degenhardt, Alexandra, Kinkel, R. Philip

“…A case of multiple sclerosis presenting during anti-tumor necrosis factor treatment for rheumatoid arthritis is discussed. This association has been reported…”
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Association between immediate initiation of intramuscular interferon beta-1a at the time of a clinically isolated syndrome and long-term outcomes: a 10-year follow-up of the Controlled High-Risk Avonex Multiple Sclerosis Prevention Study in Ongoing Neurological Surveillance by Kinkel, R Philip, Dontchev, Mariya, Kollman, Craig, Skaramagas, Thomai T, O'Connor, Paul W, Simon, Jack H

“…To determine whether immediate initiation of treatment at the time of a clinically isolated syndrome in patients at high risk for clinically definite multiple…”
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The epitope spreading cascade during progression of experimental autoimmune encephalomyelitis and multiple sclerosis by Tuohy, Vincent K., Yu, Min, Yin, Ling, Kawczak, Julie A., Johnson, Justin M., Mathisen, Peter M., Weinstock-Guttnnan, Bianca, Kinkel, R. Philip

“…We have made the following observations regarding self‐recognition during the development and progression of murine experimental autoimmune encephalomyelitis…”
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Health-related quality of life assessment in multiple sclerosis by Miller, Deborah M, Kinkel, R Philip

“…The goal of evidence-based medicine in the treatment of conditions that produce morbidity but have a minimal impact on mortality is arguably to reduce disease…”
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Acute paraplegia with vanishing white matter lesions by Jensen, Rikke M, Kinkel, R Philip

“…Young adults presenting with an acute myelopathy often represent a diagnostic challenge. We present the case of a 20-year-old man who demonstrated many of the…”
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