Search Results - "Kinkel, Mary D."

On the diabetic menu: Zebrafish as a model for pancreas development and function by Kinkel, Mary D, Prince, Victoria E

“…Development of the vertebrate pancreas is a complex stepwise process comprising regionalization, cell differentiation, and morphogenesis. Studies in zebrafish…”
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Cyp26 enzymes function in endoderm to regulate pancreatic field size by Kinkel, Mary D, Sefton, Elizabeth M, Kikuchi, Yutaka, Mizoguchi, Takamasa, Ward, Andrea B, Prince, Victoria E

“…The control of organ size and position relies, at least in part, upon appropriate regulation of the signals that specify organ progenitor fields. Pancreatic…”
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Transgenic zebrafish model of the C43G human insulin gene mutation by Eames, Stefani C, Kinkel, Mary D, Rajan, Sindhu, Prince, Victoria E, Philipson, Louis H

“…Aims/Introduction The human insulin gene/preproinsulin protein mutation C43G disrupts disulfide bond formation and causes diabetes in humans. Previous in vitro…”
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Intraperitoneal injection into adult zebrafish by Kinkel, Mary D, Eames, Stefani C, Philipson, Louis H, Prince, Victoria E

“…A convenient method for chemically treating zebrafish is to introduce the reagent into the tank water, where it will be taken up by the fish. However, this…”
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Blood sugar measurement in zebrafish reveals dynamics of glucose homeostasis by Eames, Stefani C, Philipson, Louis H, Prince, Victoria E, Kinkel, Mary D

“…The adult zebrafish has the potential to become an important model for diabetes-related research. To realize this potential, small-scale methods for analyzing…”
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Cdx4 is required in the endoderm to localize the pancreas and limit beta-cell number by Kinkel, Mary D, Eames, Stefani C, Alonzo, Martha R, Prince, Victoria E

“…Cdx transcription factors have crucial roles in anteroposterior patterning of the nervous system and mesoderm. Here we focus on the role of cdx4 in patterning…”
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Retinoids signal directly to zebrafish endoderm to specify insulin-expressing beta-cells by Stafford, David, White, Richard J, Kinkel, Mary D, Linville, Angela, Schilling, Thomas F, Prince, Victoria E

“…During vertebrate development, the endodermal germ layer becomes regionalized along its anteroposterior axis to give rise to a variety of organs, including the…”
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Recent advances in pancreas development: from embryonic pathways to programming renewable sources of beta cells by Prince, Victoria E, Kinkel, Mary D

“…In recent years, there has been significant progress in understanding the detailed mechanisms of pancreas development. These studies have in turn influenced…”
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Coordinate down-regulation of cartilage matrix gene expression in Bcl-2 deficient chondrocytes is associated with decreased SOX9 expression and decreased mRNA stability by Kinkel, Mary D., Horton Jr, Walter E.

“…The anti‐apoptotic protein Bcl‐2 has been shown to function in roles unrelated to apoptosis in a variety of cell types. We have previously reported that loss…”
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Age‐related expression patterns of Bag‐1 and Bcl‐2 in growth plate and articular chondrocytes by Kinkel, Mary D., Yagi, Rieko, McBurney, Denise, Nugent, Ashleigh, Horton, Walter E.

“…Aging cartilage displays increased chondrocyte apoptosis and decreased responsiveness of chondrocytes to growth factors. The molecular mechanisms responsible…”
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Independent test of the fourth rib aging technique by Russell, K F, Simpson, S W, Genovese, J, Kinkel, M D, Meindl, R S, Lovejoy, C O

“…The sternal surface of the 4th rib has been suggested as a useful predictor of adult age-at-death (Iscan et al.: Journal of Forensic Sciences 29:1094-1104,…”
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A grand new view from the embryo by Kinkel, Mary D., Prince, Victoria E.

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Cdx4 is required in the endoderm to localize the pancreas and limitβ -cell number by Mary D. Kinkel, Stefani C. Eames, Martha R. Alonzo, Victoria E. Prince

“…Cdx transcription factors have crucial roles in anteroposterior patterning of the nervous system and mesoderm. Here we focus on the role of cdx4 in patterning…”
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Intraperitoneal Injection into Adult Zebrafish by Kinkel, Mary D., Eames, Stefani C., Philipson, Louis H., Prince, Victoria E.

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Retinoids signal directly to zebrafish endoderm to specify insulin -expressing β-cells

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Retinoids signal directly to zebrafish endoderm to specify insulin-expressing β-cells by David Stafford, Richard J. White, Mary D. Kinkel, Angela Linville, Thomas F. Schilling, Victoria E. Prince

“…During vertebrate development, the endodermal germ layer becomes regionalized along its anteroposterior axis to give rise to a variety of organs, including the…”
Get full text