Search Results - "Kingham, Paul J."

Peripheral nerve regeneration: Experimental strategies and future perspectives by Faroni, Alessandro, Mobasseri, S. Atefeh, Kingham, Paul J., Reid, Adam J.

“…Peripheral nerve injuries represent a substantial clinical problem with insufficient or unsatisfactory treatment options. This review summarises all the events…”
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Schwann cell-like differentiated adipose stem cells promote neurite outgrowth via secreted exosomes and RNA transfer by Ching, Rosanna C, Wiberg, Mikael, Kingham, Paul J

“…Adipose derived stem cells can be stimulated to produce a growth factor rich secretome which enhances axon regeneration. In this study we investigated the…”
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Stimulating the neurotrophic and angiogenic properties of human adipose-derived stem cells enhances nerve repair by Kingham, Paul J, Kolar, Mallappa K, Novikova, Liudmila N, Novikov, Lev N, Wiberg, Mikael

“…In future, adipose-derived stem cells (ASC) might be used to treat neurological disorders. In this study, the neurotrophic and angiogenic properties of human…”
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The neurotrophic effects of different human dental mesenchymal stem cells by Kolar, Mallappa K., Itte, Vinay N., Kingham, Paul J., Novikov, Lev N., Wiberg, Mikael, Kelk, Peyman

“…The current gold standard treatment for peripheral nerve injury is nerve grafting but this has disadvantages such as donor site morbidity. New techniques focus…”
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Evaluation of growth, stemness, and angiogenic properties of dental pulp stem cells cultured in cGMP xeno-/serum-free medium by Qu, Chengjuan, Brohlin, Maria, Kingham, Paul J, Kelk, Peyman

“…This study was aimed to investigate the effects of cGMP xeno-/serum-free medium (XSF, Irvine Scientific) on the properties of human dental pulp stem cells…”
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Effect of delayed peripheral nerve repair on nerve regeneration, Schwann cell function and target muscle recovery by Jonsson, Samuel, Wiberg, Rebecca, McGrath, Aleksandra M, Novikov, Lev N, Wiberg, Mikael, Novikova, Liudmila N, Kingham, Paul J

“…Despite advances in surgical techniques for peripheral nerve repair, functional restitution remains incomplete. The timing of surgery is one factor influencing…”
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Evaluation of apoptotic pathways in dorsal root ganglion neurons following peripheral nerve injury by Wiberg, Rebecca, Novikova, Liudmila N, Kingham, Paul J

“…Peripheral nerve injuries induce significant sensory neuronal cell death in the dorsal root ganglia (DRG); however, the role of specific apoptotic pathways is…”
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Three-Dimensional Osteogenic Differentiation of Bone Marrow Mesenchymal Stem Cells Promotes Matrix Metallopeptidase 13 (MMP13) Expression in Type I Collagen Hydrogels by Oliveros Anerillas, Luis, Kingham, Paul J, Lammi, Mikko J, Wiberg, Mikael, Kelk, Peyman

“…Autologous bone transplantation is the principal method for reconstruction of large bone defects. This technique has limitations, such as donor site…”
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Neuroprotective effects of N-acetyl-cysteine and acetyl-L-carnitine after spinal cord injury in adult rats by Karalija, Amar, Novikova, Liudmila N, Kingham, Paul J, Wiberg, Mikael, Novikov, Lev N

“…Following the initial acute stage of spinal cord injury, a cascade of cellular and inflammatory responses will lead to progressive secondary damage of the…”
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Investigation of the Expression of Myogenic Transcription Factors, microRNAs and Muscle-Specific E3 Ubiquitin Ligases in the Medial Gastrocnemius and Soleus Muscles following Peripheral Nerve Injury by Wiberg, Rebecca, Jonsson, Samuel, Novikova, Liudmila N, Kingham, Paul J

“…Despite surgical innovation, the sensory and motor outcome after a peripheral nerve injury remains incomplete. One contributing factor to the poor outcome is…”
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Secretome from In Vitro Mechanically Loaded Myoblasts Induces Tenocyte Migration, Transition to a Fibroblastic Phenotype and Suppression of Collagen Production by Zhou, Xin, Li, Junhong, Giannopoulos, Antonios, Kingham, Paul J, Backman, Ludvig J

“…It is known that mechanical loading of muscles increases the strength of healing tendon tissue, but the mechanism involved remains elusive. We hypothesized…”
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Neurotrophic activity of human adipose stem cells isolated from deep and superficial layers of abdominal fat by Kalbermatten, Daniel F, Schaakxs, Dominique, Kingham, Paul J, Wiberg, Mikael

“…New approaches to the clinical treatment of traumatic nerve injuries may one day utilize stem cells to enhance nerve regeneration. Adipose-derived stem cells…”
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Phenotypic and functional characteristics of mesenchymal stem cells differentiated along a Schwann cell lineage by Caddick, Jenny, Kingham, Paul J., Gardiner, Natalie J, Wiberg, Mikael, Terenghi, Giorgio

“…We have investigated the phenotypic and bioassay characteristics of bone marrow mesenchymal stromal cells (MSCs) differentiated along a Schwann cell lineage…”
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Regenerative effects of adipose-tissue-derived stem cells for treatment of peripheral nerve injuries by Kolar, Mallappa K, Kingham, Paul J

“…Peripheral nerve injuries are a common occurrence affecting the nerves found outside the central nervous system. Complete nerve transections necessitate…”
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Efficacy of Nerve-Derived Hydrogels to Promote Axon Regeneration Is Influenced by the Method of Tissue Decellularization by Kuna, Vijay Kumar, Lundgren, Andre, Anerillas, Luis Oliveros, Kelk, Peyman, Brohlin, Maria, Wiberg, Mikael, Kingham, Paul J., Novikova, Ludmila N., Andersson, Gustav, Novikov, Lev N.

“…Injuries to large peripheral nerves are often associated with tissue defects and require reconstruction using autologous nerve grafts, which have limited…”
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Regenerative cell injection in denervated muscle reduces atrophy and enhances recovery following nerve repair by Schaakxs, Dominique, Kalbermatten, Daniel F., Raffoul, Wassim, Wiberg, Mikael, Kingham, Paul J.

“…Introduction: Functional muscle recovery after peripheral nerve injury is far from optimal, partly due to atrophy of the muscle arising from prolonged…”
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Platelet lysate for expansion or osteogenic differentiation of bone marrow mesenchymal stem cells for 3D tissue constructs by Anerillas, Luis Oliveros, Wiberg, Mikael, Kingham, Paul J., Kelk, Peyman

“…BackgroundThe use of mesenchymal stem cells (MSCs) for the development of tissue-engineered constructs has advanced in recent years. However, future clinically…”
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Aging effect on neurotrophic activity of human mesenchymal stem cells by Brohlin, Maria, Kingham, Paul J, Novikova, Liudmila N, Novikov, Lev N, Wiberg, Mikael

“…Clinical efficacy of stem cells for nerve repair is likely to be influenced by issues including donor age and in vitro expansion time. We isolated human…”
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The role of exosomes in peripheral nerve regeneration by Ching, Rosanna C, Kingham, Paul J

“…Peripheral nerve injuries remain problematic to treat, with poor functional recovery commonly observed. Injuries resulting in a nerve gap create specific…”
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The potential role of collagen type VII in breast cancer proliferation by Pérez-Díaz, Sergio, Lindberg, Jessica, Anerillas, Luis Oliveros, Kingham, Paul J, Sund, Malin, Rask, Gunilla, Svensson, Johan, Jansson, Malin, Wiberg, Rebecca

“…Breast cancer is the most common cancer in women. Cancer cells can persist in a prolonged dormant state for years without any clinical evidence of disease…”
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