Search Results - "King, Shelby M"

The Pharmacological Potential of Adenosine A2A Receptor Antagonists for Treating Parkinson’s Disease by Mori, Akihisa, Chen, Jiang-Fan, Uchida, Shinichi, Durlach, Cecile, King, Shelby M., Jenner, Peter

“…The adenosine A2A receptor subtype is recognized as a non-dopaminergic pharmacological target for the treatment of neurodegenerative disorders, notably…”
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The impact of ovulation on fallopian tube epithelial cells: evaluating three hypotheses connecting ovulation and serous ovarian cancer by King, Shelby M, Hilliard, Tyvette S, Wu, Lucia Y, Jaffe, Randal C, Fazleabas, Asgerally T, Burdette, Joanna E

“…Ovarian cancer is the most lethal gynecological malignancy affecting American women. Current hypotheses concerning the etiology of ovarian cancer propose that…”
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Istradefylline effects on tremor dominance (TD) and postural instability and gait difficulty (PIGD) by Torres-Yaghi, Yasar, Hattori, Nobutaka, Rascol, Olivier, Nakajima, Yu, King, Shelby M., Mori, Akihisa, Pagan, Fernando

“…In patients with Parkinson’s Disease (PD), two distinct motor subtypes, tremor dominant (TD) and postural instability and gait difficulty (PIGD), can be…”
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A new sperm-specific Na + /H + Exchanger required for sperm motility and fertility by Garbers, David L, Wang, Dan, King, Shelby M, Quill, Timothy A, Doolittle, Lynda K

“…It has long been speculated that intracellular pH is a critical regulator of both invertebrate and vertebrate sperm motility, and sodium-hydrogen exchange has…”
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Mutation or loss of p53 differentially modifies TGFβ action in ovarian cancer by Ó hAinmhire, Eoghainín, Quartuccio, Suzanne M, Cheng, Whay, Ahmed, Roshan A, King, Shelby M, Burdette, Joanna E

“…Ovarian cancer is the most lethal gynecological disease affecting women in the US. The Cancer Genome Atlas Network identified p53 mutations in 96% of…”
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Phosphatidylinositol 3,4,5-trisphosphate localization in recycling endosomes is necessary for AP-1B-dependent sorting in polarized epithelial cells by Fields, Ian C, King, Shelby M, Shteyn, Elina, Kang, Richard S, Fölsch, Heike

“…Polarized epithelial cells coexpress two almost identical AP-1 clathrin adaptor complexes: the ubiquitously expressed AP-1A and the epithelial cell-specific…”
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Evaluating the progenitor cells of ovarian cancer: analysis of current animal models by King, Shelby M., University of Illinois at Chicago, Chicago, IL, USA, Burdette, Joanna E., University of Illinois at Chicago, Chicago, IL, USA

“…Serous ovarian cancer is one of the most lethal gynecological malignancies. Progress on effective diagnostics and therapeutics for this disease are hampered by…”
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Modeling Tumor Phenotypes In Vitro with Three-Dimensional Bioprinting by Langer, Ellen M., Allen-Petersen, Brittany L., King, Shelby M., Kendsersky, Nicholas D., Turnidge, Megan A., Kuziel, Genevra M., Riggers, Rachelle, Samatham, Ravi, Amery, Taylor S., Jacques, Steven L., Sheppard, Brett C., Korkola, James E., Muschler, John L., Thibault, Guillaume, Chang, Young Hwan, Gray, Joe W., Presnell, Sharon C., Nguyen, Deborah G., Sears, Rosalie C.

“…The tumor microenvironment plays a critical role in tumor growth, progression, and therapeutic resistance, but interrogating the role of specific tumor-stromal…”
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3D Proximal Tubule Tissues Recapitulate Key Aspects of Renal Physiology to Enable Nephrotoxicity Testing by King, Shelby M, Higgins, J William, Nino, Celina R, Smith, Timothy R, Paffenroth, Elizabeth H, Fairbairn, Casey E, Docuyanan, Abigail, Shah, Vishal D, Chen, Alice E, Presnell, Sharon C, Nguyen, Deborah G

“…Due to its exposure to high concentrations of xenobiotics, the kidney proximal tubule is a primary site of nephrotoxicity and resulting attrition in the drug…”
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Early transformative changes in normal ovarian surface epithelium induced by oxidative stress require Akt upregulation, DNA damage and epithelial-stromal interaction by King, Shelby M, Quartuccio, Suzanne M, Vanderhyden, Barbara C, Burdette, Joanna E

“…Ovarian cancer is the deadliest gynecological malignancy due to detection of cancer at a late stage when the disease has metastasized. One likely progenitor…”
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3D Proximal Tubule Tissues Recapitulate Key Aspects of Renal Physiology to Enable Nephrotoxicity Testing by King, Shelby M., Higgins, J. William, Nino, Celina R., Smith, Timothy R., Paffenroth, Elizabeth H., Fairbairn, Casey E., Docuyanan, Abigail, Shah, Vishal D., Chen, Alice E., Presnell, Sharon C., Nguyen, Deborah G.

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Evaluating the progenitor cells of ovarian cancer: analysis of current animal models by King, Shelby M, Burdette, Joanna E

“…Serous ovarian cancer is one of the most lethal gynecological malignancies. Progress on effective diagnostics and therapeutics for this disease are hampered by…”
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Abstract 2034: Development of 3D bioprinted human breast cancer for in vitro drug screening by King, Shelby M., Presnell, Sharon C., Nguyen, Deborah G.

“…Abstract As breast cancer is a disease of multiple cell types in which the growth, invasion, and metastasis of epithelial carcinomas is heavily influenced by…”
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Alginate hydrogels for three-dimensional organ culture of ovaries and oviducts by King, Shelby M, Quartuccio, Suzanne, Hilliard, Tyvette S, Inoue, Kari, Burdette, Joanna E

“…Ovarian cancer is the fifth leading cause of cancer deaths in women and has a 63% mortality rate in the United States(1). The cell type of origin for ovarian…”
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Insulin and insulin-like growth factor signaling increases proliferation and hyperplasia of the ovarian surface epithelium and decreases follicular integrity through upregulation of the PI3-kinase pathway by King, Shelby M, Modi, Dimple A, Eddie, Sharon L, Burdette, Joanna E

“…The ovarian surface epithelium responds to cytokines and hormonal cues to initiate proliferation and migration following ovulation. Although insulin and IGF…”
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The Pharmacological Potential of Adenosine A 2A Receptor Antagonists for Treating Parkinson's Disease by Mori, Akihisa, Chen, Jiang-Fan, Uchida, Shinichi, Durlach, Cecile, King, Shelby M, Jenner, Peter

“…The adenosine A receptor subtype is recognized as a non-dopaminergic pharmacological target for the treatment of neurodegenerative disorders, notably…”
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Transformation of Normal Ovarian Surface Epithelium by Oxidative Stress Requires Akt Upregulation and Activation by King, Shelby M., Patel, Roshni S., Burdette, Joanna E.

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Mutation or Loss of p53 Differentially Modifies TGF[beta] Action in Ovarian Cancer by Ó hAinmhire, Eoghainín, Quartuccio, Suzanne M, Cheng, Whay, Ahmed, Roshan A, King, Shelby M, Burdette, Joanna E

“…Ovarian cancer is the most lethal gynecological disease affecting women in the US. The Cancer Genome Atlas Network identified p53 mutations in 96% of…”
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Ovulation Generates Oxidative Stress That Induces DNA Damage in Tubal Epithelial Cells by King, Shelby M., Hilliard, Tyvette S., Wu, Lucia Y., Fazleabas, Asgerally T., Burdette, Joanna E.

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Alginate Hydrogels for Three-Dimensional Organ Culture of Ovaries and Oviducts by King, Shelby M., Quartuccio, Suzanne, Hilliard, Tyvette S., Inoue, Kari, Burdette, Joanna E.

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