Search Results - "King, N.Paul"
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Steric and electronic limitations for the Dötz benzannulation of aromatic alkynes
Published in Tetrahedron letters (20-05-2002)“…As part of an investigation into a new strategy for biaryl synthesis, the Dötz benzannulation of a series of substituted aryl acetylenes was undertaken to…”
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Studies into diastereoselective Dötz benzannulations for the synthesis of axially chiral biaryls
Published in Tetrahedron letters (13-10-2003)“…A series of racemic chiral ortho substituents on 1-phenylhex-1-yne have been found to control the atroposelective formation of a biaryl from Dötz…”
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3
Heterocyclic synthesis by CC bond formation. Tetrahydrofuran and tetrahydropyran synthesis via oxonium ion-mediated cyclisation reactions
Published in Tetrahedron letters (08-12-1997)“…Dimethyl(methylthio)sulfonium tetrafluoroborate triggers ionisation and cyclisation of hemithioacetals 3 to give tetrahydrofurans 8–11 in good yields and…”
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4
Synthesis and biological properties of C12,13-cyclopropylepothilone A and related epothilones
Published in Chemistry & biology (01-07-1998)“…Background: The epothilones are natural substances that are potently cytotoxic, having an almost identical mode of action to Taxol TM as tubulin-polymerization…”
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