Search Results - "King, Matthew"
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Phase separation of TPX2 enhances and spatially coordinates microtubule nucleation
Published in Nature communications (14-01-2020)“…Phase separation of substrates and effectors is proposed to enhance biological reaction rates and efficiency. Targeting protein for Xklp2 (TPX2) is an effector…”
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The Contents Are the Vessel: Snod bcud Beyond Nature
Published in Journal of global Buddhism (01-06-2024)“…Reflecting on the implications of Dipesh Chakrabarty's "The Climate of History" for a critical Buddhist Studies of/for the Anthropocene, this article…”
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Molecular mechanism of biased signaling in a prototypical G protein-coupled receptor
Published in Science (American Association for the Advancement of Science) (21-02-2020)“…Biased signaling, in which different ligands that bind to the same G protein-coupled receptor preferentially trigger distinct signaling pathways, holds great…”
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A chromosome-scale assembly of the sorghum genome using nanopore sequencing and optical mapping
Published in Nature communications (19-11-2018)“…Long-read sequencing technologies have greatly facilitated assemblies of large eukaryotic genomes. In this paper, Oxford Nanopore sequences generated on a…”
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Augmin is a Ran-regulated spindle assembly factor
Published in The Journal of biological chemistry (01-06-2023)“…Mitotic spindles are composed of microtubules (MTs) that must nucleate at the right place and time. Ran regulates this process by directly controlling the…”
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Effects of Solvent Stabilization on Pharmaceutical Crystallization: Investigating Conformational Polymorphism of Probucol Using Combined Solid-State Density Functional Theory, Molecular Dynamics, and Terahertz Spectroscopy
Published in The journal of physical chemistry. A, Molecules, spectroscopy, kinetics, environment, & general theory (15-08-2019)“…Solid-state density functional theory (DFT), molecular dynamics (MD), and terahertz (THz) spectroscopy were used to study the formation of enantiotropically…”
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Interaction of spindle assembly factor TPX2 with importins-α/β inhibits protein phase separation
Published in The Journal of biological chemistry (01-09-2021)“…The microtubule-based mitotic spindle is responsible for equally partitioning the genome during each cell division, and its assembly is executed via several…”
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8
Let’s take the dog for a gait
Published in Gait & posture (01-06-2020)“…•“Gait” has become synonymous with walking.•“Gait” is used to describe the pattern of locomotion, not locomotion itself.•Greater need is required for the use…”
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A novel assay provides sensitive measurement of physiologically relevant changes in albumin permeability in isolated human and rodent glomeruli
Published in Kidney international (01-05-2018)“…Increased urinary albumin excretion is a key feature of glomerular disease but has limitations as a measure of glomerular permeability. Here we describe a…”
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A simple derivation of the mean of the Sackin index of tree balance under the uniform model on rooted binary labeled trees
Published in Mathematical biosciences (01-12-2021)“…In mathematical phylogenetics, the Sackin index, measuring the sum of path lengths between leaves and the root, is one of the most frequently used measures of…”
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Identification and Quantification of Polymorphism in the Pharmaceutical Compound Diclofenac Acid by Terahertz Spectroscopy and Solid-State Density Functional Theory
Published in Analytical chemistry (Washington) (15-05-2011)“…Polymorph detection and quantification in crystalline materials is a principle interest of the pharmaceutical industry. Terahertz (THz) spectroscopy can be…”
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Mechanism of how augmin directly targets the γ-tubulin ring complex to microtubules
Published in The Journal of cell biology (02-07-2018)“…Microtubules (MTs) must be generated from precise locations to form the structural frameworks required for cell shape and function. MTs are nucleated by the…”
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How effective are exercises delivered digitally (requiring internet), amongst patients with hip or knee osteoarthritis? A systematic review and meta-analysis
Published in Osteoarthritis and cartilage (01-03-2024)“…The aim of this systematic review and meta-analysis is to describe the effect of digitally delivered exercise on pain, physical function and quality of life…”
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Emergent microenvironments of nucleoli
Published in Nucleus (Austin, Tex.) (01-12-2024)“…In higher eukaryotes, the nucleolus harbors at least three sub-phases that facilitate multiple functionalities including ribosome biogenesis. The three…”
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Relationships between cerebrospinal fluid GABAergic neurosteroid levels and symptom severity in men with PTSD
Published in Psychoneuroendocrinology (01-04-2019)“…•CSF allopregnanolone and pregnanolone levels are related to PTSD severity in men.•CSF allopregnanolone + pregnanolone to DHEA is related to dysphoria…”
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Data Mining in Psychological Treatment Research: A Primer on Classification and Regression Trees
Published in Journal of consulting and clinical psychology (01-10-2014)“…Data mining of treatment study results can reveal unforeseen but critical insights, such as who receives the most benefit from treatment and under what…”
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Predicting response to Cognitive Processing Therapy for PTSD: A machine-learning approach
Published in Behaviour research and therapy (01-09-2021)“…Cognitive Processing Therapy (CPT) is an effective treatment for posttraumatic stress disorder (PTSD); however, not every client achieves optimal outcomes…”
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Efficacy of non-surgical management and functional outcomes of partial ACL tears. A systematic review of randomised trials
Published in BMC musculoskeletal disorders (08-04-2022)“…The incidence of anterior cruciate ligament (ACL) injuries represents a large burden of knee injuries in both the general and sporting populations, often…”
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Vascularized Pedicled Fibula for Pediatric Tibia Reconstruction
Published in Journal of orthopaedic trauma (01-08-2021)“…This video reviews the technique of a vascularized fibula flap for pediatric tibia reconstruction. A 4-year-old boy with a history of a left tibial infected…”
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