Search Results - "King, Lloyd"

Alopecia areata by Pratt, C. Herbert, King, Lloyd E., Messenger, Andrew G., Christiano, Angela M., Sundberg, John P.

“…Alopecia areata is an autoimmune disorder characterized by transient, non-scarring hair loss and preservation of the hair follicle. Hair loss can take many…”
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Salmonella-induced thrombi in mice develop asynchronously in the spleen and liver and are not effective bacterial traps by Beristain-Covarrubias, Nonantzin, Perez-Toledo, Marisol, Flores-Langarica, Adriana, Zuidscherwoude, Malou, Hitchcock, Jessica R., Channell, Will M., King, Lloyd D.W., Thomas, Mark R., Henderson, Ian R., Rayes, Julie, Watson, Steve P., Cunningham, Adam F.

“…Thrombosis is a frequent, life-threatening complication of systemic infection associated with multiple organ damage. We have previously described a novel…”
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Identification of an extracellular bacterial flavoenzyme that can prevent re-polymerisation of lignin fragments by Rahmanpour, Rahman, King, Lloyd D.W., Bugg, Timothy D.H.

“…A significant problem in the oxidative breakdown of lignin is the tendency of phenolic radical fragments to re-polymerise to form higher molecular weight…”
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Human Basigin (CD147) Does Not Directly Interact with SARS-CoV-2 Spike Glycoprotein by Ragotte, Robert J, Pulido, David, Donnellan, Francesca R, Hill, Michelle L, Gorini, Giacomo, Davies, Hannah, Brun, Juliane, McHugh, Kirsty, King, Lloyd D W, Skinner, Katherine, Miura, Kazutoyo, Long, Carole A, Zitzmann, Nicole, Draper, Simon J

“…Basigin, or CD147, has been reported as a coreceptor used by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) to invade host cells. Basigin also…”
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Analyses of human vaccine-specific circulating and bone marrow-resident B cell populations reveal benefit of delayed vaccine booster dosing with blood-stage malaria antigens by Barrett, Jordan R, Silk, Sarah E, Mkindi, Catherine G, Kwiatkowska, Karolina M, Hou, Mimi M, Lias, Amelia M, Kalinga, Wilmina F, Mtaka, Ivanny M, McHugh, Kirsty, Bardelli, Martino, Davies, Hannah, King, Lloyd D W, Edwards, Nick J, Chauhan, Virander S, Mukherjee, Paushali, Rwezaula, Stella, Chitnis, Chetan E, Olotu, Ally I, Minassian, Angela M, Draper, Simon J, Nielsen, Carolyn M

“…We have previously reported primary endpoints of a clinical trial testing two vaccine platforms for the delivery of malaria DBPRII: viral vectors (ChAd63,…”
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Rational structure-guided design of a blood stage malaria vaccine immunogen presenting a single epitope from PfRH5 by Harrison, Thomas E, Alam, Nawsad, Farrell, Brendan, Quinkert, Doris, Lias, Amelia M, King, Lloyd D W, Barfod, Lea K, Draper, Simon J, Campeotto, Ivan, Higgins, Matthew K

“…There is an urgent need for improved malaria vaccine immunogens. Invasion of erythrocytes by Plasmodium falciparum is essential for its life cycle, preceding…”
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Development and application of an enantioselective liquid chromatography – tandem mass spectrometry method for the quantification of enantiomers to evaluate in vivo chiral inversion in beagle dog by Shah, Syeda A., Jairaj, Mark, King, Lloyd

“…•A chiral stereoselective method was developed and validated.•Suspected In-vivo metabolic chiral inversion was investigated.•Protein precipitation was applied…”
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Estrogen regulates the expression of retinoic acid synthesis enzymes and binding proteins in mouse skin by Everts, Helen B., Silva, Kathleen A., Schmidt, Adriana N., Opalenik, Susan, Duncan, F. Jason, King, Lloyd E., Sundberg, John P., Ong, David E.

“…Topical 17-beta-estradiol (E2) regulates the hair cycle, hair shaft differentiation, and sebum production. Vitamin A also regulates sebum production. Vitamin A…”
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Plug and play virus-like particles for the generation of anti-toxin antibodies by Edge, Rebecca J., Marriott, Amy E., Stars, Emma L., Patel, Rohit N., Wilkinson, Mark C., King, Lloyd D.W., Slagboom, Julien, Tan, Choo Hock, Ratanabanangkoon, Kavi, Draper, Simon J., Ainsworth, Stuart

“…Snakebite is a major global health concern, for which antivenom remains the only approved treatment to neutralise the harmful effects of the toxins. However,…”
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IgG Responses to Porins and Lipopolysaccharide within an Outer Membrane-Based Vaccine against Nontyphoidal Salmonella Develop at Discordant Rates by Schager, Anna E, Dominguez-Medina, C Coral, Necchi, Francesca, Micoli, Francesca, Goh, Yun Shan, Goodall, Margaret, Flores-Langarica, Adriana, Bobat, Saeeda, Cook, Charlotte N L, Arcuri, Melissa, Marini, Arianna, King, Lloyd D W, Morris, Faye C, Anderson, Graham, Toellner, Kai-Michael, Henderson, Ian R, López-Macías, Constantino, MacLennan, Calman A, Cunningham, Adam F

“…Antibodies acquired after vaccination or natural infection with Gram-negative bacteria, such as invasive serovar Typhimurium, can protect against disease…”
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A protective role for matrix metalloproteinase-3 in squamous cell carcinoma by MCCAWLEY, Lisa J, CRAWFORD, Howard C, KING, Lloyd E, MUDGETT, John, MATRISIAN, Lynn M

“…Elevated expression of matrix metalloproteinase-3 (MMP-3/stromelysin-1) is associated with a variety of tumor types, although its in vivo functional role…”
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Superior antibody immunogenicity of a viral-vectored RH5 blood-stage malaria vaccine in Tanzanian infants as compared to adults by Silk, Sarah E, Kalinga, Wilmina F, Mtaka, Ivanny M, Lilolime, Nasoro S, Mpina, Maximillian, Milando, Florence, Ahmed, Saumu, Diouf, Ababacar, Mkwepu, Fatuma, Simon, Beatus, Athumani, Thabit, Rashid, Mohammed, Mohammed, Latipha, Lweno, Omary, Ali, Ali M, Nyaulingo, Gloria, Mwalimu, Bakari, Mswata, Sarah, Mwamlima, Tunu G, Barrett, Jordan R, Wang, Lawrence T, Themistocleous, Yrene, King, Lloyd D W, Hodgson, Susanne H, Payne, Ruth O, Nielsen, Carolyn M, Lawrie, Alison M, Nugent, Fay L, Cho, Jee-Sun, Long, Carole A, Miura, Kazutoyo, Draper, Simon J, Minassian, Angela M, Olotu, Ally I

“…RH5 is a leading blood-stage candidate antigen for a Plasmodium falciparum vaccine; however, its safety and immunogenicity in malaria-endemic populations are…”
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Alopecia areata investigational assessment guidelines--Part II. National Alopecia Areata Foundation by Olsen, Elise A, Hordinsky, Maria K, Price, Vera H, Roberts, Janet L, Shapiro, Jerry, Canfield, Doug, Duvic, Madeleine, King, Jr, Lloyd E, McMichael, Amy J, Randall, Valerie A, Turner, Maria L, Sperling, Leonard, Whiting, David A, Norris, David

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Cicatricial Alopecia Research Foundation meeting, May 2016: Progress towards the diagnosis, treatment and cure of primary cicatricial alopecias by Sundberg, John P., Hordinsky, Maria K., Bergfeld, Wilma, Lenzy, Yolanda M., McMichael, Amy J., Christiano, Angela M., McGregor, Tracy, Stenn, Kurt S., Sivamani, Raja K., Pratt, Craig Herbert, King, Lloyd E.

“…Primary cicatricial alopecias (PCAs) are a group of skin diseases in which there is progressive and permanent destruction of hair follicles followed by…”
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Animal Models for Alopecia Areata: What and Where? by Sundberg, John P, McElwee, Kevin, Brehm, Michael A, Su, Lishan, King, Jr, Lloyd E

“…Disease is not limited to humans. Rather, humans are but another mammal in a continuum, and as such, often share similar if not identical diseases with other…”
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Skin Diseases in Laboratory Mice: Approaches to Drug Target Identification and Efficacy Screening by Sundberg, John P, Silva, Kathleen A, King, Jr, Lloyd E, Pratt, C Herbert

“…A large variety of mouse models for human skin, hair, and nail diseases are readily available from investigators and vendors worldwide. Mouse skin is a simple…”
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Increased Expression of Cxcr3 and Its Ligands, Cxcl9 and Cxcl10, during the Development of Alopecia Areata in the Mouse by McPhee, Caroline G., Jason Duncan, F., Silva, Kathleen A., King, Lloyd E., HogenEsch, Harm, Roopenian, Derry C., Everts, Helen B., Sundberg, John P.

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Oestrogen receptor-β expression in melanocytic lesions by Schmidt, Adriana N., Nanney, Lillian B., Boyd, Alan S., King Jr, Lloyd E., Ellis, Darrel L.

“…:  Melanomas rarely occur before puberty, have a higher death rate for males, and tend to be more invasive during pregnancy. Prior to the discovery of a second…”
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Endogenous Retinoids in the Pathogenesis of Alopecia Areata by Duncan, F. Jason, Silva, Kathleen A., Johnson, Charles J., King, Benjamin L., Szatkiewicz, Jin P., Kamdar, Sonya P., Ong, David E., Napoli, Joseph L., Wang, Jinshan, King, Lloyd E., Whiting, David A., McElwee, Kevin J., Sundberg, John P., Everts, Helen B.

“…Alopecia areata (AA) is an autoimmune disease that attacks anagen hair follicles. Gene array in graft-induced C3H/HeJ mice revealed that genes involved in…”
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Preclinical development of a stabilized RH5 virus-like particle vaccine that induces improved antimalarial antibodies by King, Lloyd D.W., Pulido, David, Barrett, Jordan R., Davies, Hannah, Quinkert, Doris, Lias, Amelia M., Silk, Sarah E., Pattinson, David J., Diouf, Ababacar, Williams, Barnabas G., McHugh, Kirsty, Rodrigues, Ana, Rigby, Cassandra A., Strazza, Veronica, Suurbaar, Jonathan, Rees-Spear, Chloe, Dabbs, Rebecca A., Ishizuka, Andrew S., Zhou, Yu, Gupta, Gaurav, Jin, Jing, Li, Yuanyuan, Carnrot, Cecilia, Minassian, Angela M., Campeotto, Ivan, Fleishman, Sarel J., Noe, Amy R., MacGill, Randall S., King, C. Richter, Birkett, Ashley J., Soisson, Lorraine A., Long, Carole A., Miura, Kazutoyo, Ashfield, Rebecca, Skinner, Katherine, Howarth, Mark R., Biswas, Sumi, Draper, Simon J.

“…Plasmodium falciparum reticulocyte-binding protein homolog 5 (RH5) is a leading blood-stage malaria vaccine antigen target, currently in a phase 2b clinical…”
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