Search Results - "King, Jason"

The origins and evolution of macropinocytosis by King, Jason S, Kay, Robert R

“…In macropinocytosis, cells take up micrometre-sized droplets of medium into internal vesicles. These vesicles are acidified and fused to lysosomes, their…”
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Drinking problems: mechanisms of macropinosome formation and maturation by Buckley, Catherine M., King, Jason S.

“…Macropinocytosis is a mechanism for the nonspecific bulk uptake and internalisation of extracellular fluid. This plays specific and distinct roles in diverse…”
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The ESCRT and autophagy machineries cooperate to repair ESX-1-dependent damage at the Mycobacterium-containing vacuole but have opposite impact on containing the infection by López-Jiménez, Ana T, Cardenal-Muñoz, Elena, Leuba, Florence, Gerstenmaier, Lilli, Barisch, Caroline, Hagedorn, Monica, King, Jason S, Soldati, Thierry

“…Phagocytic cells capture and kill most invader microbes within the bactericidal phagosome, but some pathogens subvert killing by damaging the compartment and…”
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Dynamic Rac1 inhibition by CYRI helps cells drink, but stops them from driving by King, Jason S

“…In this issue, Le et al. (2021. J. Cell Biol.https://doi.org/10.1083/jcb.202012114) describe a new role for the recently discovered protein CYRI in controlling…”
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Editorial Essay by Jason King

“…Outgoing Editor of the Journal of Moral Theology reflects on the experience of leading the journal for the past five years…”
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The breadth of macropinocytosis research by Swanson, Joel A, King, Jason S

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Improving formaldehyde consumption drives methanol assimilation in engineered E. coli by Woolston, Benjamin M., King, Jason R., Reiter, Michael, Van Hove, Bob, Stephanopoulos, Gregory

“…Due to volatile sugar prices, the food vs fuel debate, and recent increases in the supply of natural gas, methanol has emerged as a promising feedstock for the…”
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Mycobacterium marinum antagonistically induces an autophagic response while repressing the autophagic flux in a TORC1- and ESX-1-dependent manner by Cardenal-Muñoz, Elena, Arafah, Sonia, López-Jiménez, Ana Teresa, Kicka, Sébastien, Falaise, Alexandra, Bach, Frauke, Schaad, Olivier, King, Jason S, Hagedorn, Monica, Soldati, Thierry

“…Autophagy is a eukaryotic catabolic process also participating in cell-autonomous defence. Infected host cells generate double-membrane autophagosomes that…”
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Cellular microbiology interview—Dr. Jason King by King, Jason S.

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PIKfyve/Fab1 is required for efficient V-ATPase and hydrolase delivery to phagosomes, phagosomal killing, and restriction of Legionella infection by Buckley, Catherine M, Heath, Victoria L, Guého, Aurélie, Bosmani, Cristina, Knobloch, Paulina, Sikakana, Phumzile, Personnic, Nicolas, Dove, Stephen K, Michell, Robert H, Meier, Roger, Hilbi, Hubert, Soldati, Thierry, Insall, Robert H, King, Jason S

“…By engulfing potentially harmful microbes, professional phagocytes are continually at risk from intracellular pathogens. To avoid becoming infected, the host…”
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Water loss regulates cell and vesicle volume by King, Jason S, Smythe, Elizabeth

“…Active control of vesicle water content ensures that cell size is maintained when extracellular fluid is taken up When cells take up extracellular fluid by…”
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Mechanical stress meets autophagy: potential implications for physiology and pathology by King, Jason S

“…Changes in the mechanical environment are a universal challenge for cells, and mechanical cues regulate tissue structure and cell physiology throughout life…”
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Autophagy across the eukaryotes: Is S. cerevisiae the odd one out? by King, Jason S.

“…Autophagy is conserved throughout the eukaryotes and for many years, work in Saccharomyces cerevisiae has been at the forefront of autophagy research. However…”
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Making cups and rings: the 'stalled-wave' model for macropinocytosis by Kay, Robert R, Lutton, Judith E, King, Jason S, Bretschneider, Till

“…Macropinocytosis is a broadly conserved endocytic process discovered nearly 100 years ago, yet still poorly understood. It is prominent in cancer cell feeding,…”
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Katnip is needed to maintain microtubule function and lysosomal delivery to autophagosomes and phagosomes by Starling, Georgina P, Phillips, Ben A, Ganesh, Sahana, King, Jason S

“…The efficient delivery of lysosomes is essential for many cell functions, such as the degradation of unwanted intracellular components by autophagy and the…”
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The endocytic pathways of Dictyostelium discoideum by Vines, James H, King, Jason S

“…The formation and processing of vesicles from the cell surface serves many important cellular functions ranging from nutrient acquisition to regulating the…”
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Coordinated Ras and Rac Activity Shapes Macropinocytic Cups and Enables Phagocytosis of Geometrically Diverse Bacteria by Buckley, Catherine M., Pots, Henderikus, Gueho, Aurelie, Vines, James H., Munn, Christopher J., Phillips, Ben A., Gilsbach, Bernd, Traynor, David, Nikolaev, Anton, Soldati, Thierry, Parnell, Andrew J., Kortholt, Arjan, King, Jason S.

“…Engulfment of extracellular material by phagocytosis or macropinocytosis depends on the ability of cells to generate specialized cup-shaped protrusions. To…”
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The induction of autophagy by mechanical stress by King, Jason S., Veltman, Douwe M., Insall, Robert H

“…The ability to respond and adapt to changes in the physical environment is a universal and essential cellular property. Here we demonstrated that cells respond…”
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Formation and closure of macropinocytic cups in Dictyostelium by Lutton, Judith E, Coker, Helena L E, Paschke, Peggy, Munn, Christopher J, King, Jason S, Bretschneider, Till, Kay, Robert R

“…Macropinocytosis is a conserved endocytic process by which cells engulf droplets of medium into micron-sized vesicles. We use light-sheet microscopy to define…”
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Mechanisms of Pulse Modulated Holmium:YAG Lithotripsy by King, Jason B, Katta, Nitesh, Teichman, Joel M H, Tunnell, James W, Milner, Thomas E

“…This study aimed at answering three research questions: (1) Under the experimental conditions studied, what is the dominant mechanism of Holmium:YAG…”
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