Search Results - "King, J.N."

Evaluation of the dose–response relationship of oral robenacoxib in urate crystal‐induced acute stifle synovitis in dogs by Borer, L.R., Seewald, W., Peel, J.E., King, J.N.

“…The objective of the study was to establish the dose–response relationship for robenacoxib, a selective cyclooxygenase (COX)‐2 inhibitor, in a urate crystal…”
Get full text

In vitro and ex vivo inhibition of canine cyclooxygenase isoforms by robenacoxib: A comparative study by King, J.N., Rudaz, C., Borer, L., Jung, M., Seewald, W., Lees, P.

“…In vitro whole blood canine assays were used to quantify the inhibitory actions of the novel non-steroidal anti-inflammatory drug (NSAID) robenacoxib on the…”
Get full text

In vitro and ex vivo inhibition of COX isoforms by robenacoxib in the cat: a comparative study by SCHMID, V.B, SEEWALD, W, LEES, P, KING, J.N

“…Schmid, V.B., Seewald, W., Lees, P., King, J.N. In vitro and ex vivo inhibition of COX isoforms by robenacoxib in the cat: a comparative study. J. vet…”
Get full text

Population pharmacokinetic analysis of blood concentrations of robenacoxib in dogs with osteoarthritis by Fink, M., Letellier, I., Peyrou, M., Mochel, J.P., Jung, M., King, J.N., Gruet, P., Giraudel, J.M.

“…The purpose of this analysis was to investigate whether the recommended daily dosage of 1–2mg/kg robenacoxib provides consistent exposure when administered to…”
Get full text

Treatment of separation anxiety in dogs with clomipramine: results from a prospective, randomized, double-blind, placebo-controlled, parallel-group, multicenter clinical trial by King, J.N., Simpson, B.S., Overall, K.L., Appleby, D., Pageat, P., Ross, C., Chaurand, J.P., Heath, S., Beata, C., Weiss, A.B., Muller, G., Paris, T., Bataille, B.G., Parker, J., Petit, S., Wren, J.

“…The efficacy and tolerability of clomipramine in the treatment of separation anxiety in dogs was tested in a prospective, randomized, double-blind,…”
Get full text

Results of a follow-up investigation to a clinical trial testing the efficacy of clomipramine in the treatment of separation anxiety in dogs by King, J.N., Overall, K.L., Appleby, D., Simpson, B.S., Beata, C., Chaurand, C.J.P., Heath, S.E., Ross, C., Weiss, A.B., Muller, G., Bataille, B.G., Paris, T., Pageat, P., Brovedani, F., Garden, C., Petit, S.

“…The objective of the study was to investigate the incidence of adverse events and changes in behaviour after use of clomipramine to treat separation anxiety in…”
Get full text

Efficacy and Safety of Injectable Robenacoxib for the Treatment of Pain Associated With Soft Tissue Surgery in Dogs by Friton, G., Thompson, C., Karadzovska, D., King, S., King, J.N.

“…Background Nonsteroidal anti‐inflammatory drugs (NSAIDs) are used routinely to control pain and inflammation after surgery in dogs. Robenacoxib is a…”
Get full text

Effects of Benazepril on Survival of Dogs with Chronic Kidney Disease: A Multicenter, Randomized, Blinded, Placebo‐Controlled Clinical Trial by King, J.N., Font, A., Rousselot, J.‐F., Ash, R.A., Bonfanti, U., Brovida, C., Crowe, I.D., Lanore, D., Pechereau, D., Seewald, W., Strehlau, G.

“…Background Chronic kidney disease (CKD) is an important cause of morbidity and mortality in dogs. Objective To evaluate the efficacy in prolonging survival and…”
Get full text

Determination of cobalt, copper, mercury, and nickel as bis(2-hydroxyethyl)dithiocarbamate complexes by high-performance liquid chromatography by King, Jeffrey N, Fritz, James S

Get full text

Differential pharmacokinetics and pharmacokinetic/pharmacodynamic modelling of robenacoxib and ketoprofen in a feline model of inflammation by Pelligand, L, King, J. N, Hormazabal, V, Toutain, P. L, Elliott, J, Lees, P

“…Robenacoxib and ketoprofen are acidic nonsteroidal anti‐inflammatory drugs (NSAIDs). Both are licensed for once daily administration in the cat, despite having…”
Get full text

Canine dilated cardiomyopathy: a retrospective study of prognostic findings in 367 clinical cases by Martin, M.W.S, StaffordJohnson, M.J, Strehlau, G, King, J.N

“…O bjective: To review the association between clinical signs and diagnostic findings and the survival time of dogs with dilated cardiomyopathy (DCM), and any…”
Get full text

Analytical determination and pharmacokinetics of robenacoxib in the dog by JUNG, M, LEES, P, SEEWALD, W, KING, J.N

“…An analytical method was developed and validated for the measurement of the novel analgesic and anti-inflammatory drug robenacoxib in blood and plasma of dogs…”
Get full text

Preclinical pharmacology of robenacoxib: a novel selective inhibitor of cyclooxygenase-2 by KING, J.N, DAWSON, J, ESSER, R.E, FUJIMOTO, R, KIMBLE, E.F, MANIARA, W, MARSHALL, P.J, O'BYRNE, L, QUADROS, E, TOUTAIN, P.L, LEES, P

“…This manuscript reports the results of preclinical studies in the rat with robenacoxib, a novel selective cyclooxygenase (COX)-2 inhibitor. Robenacoxib…”
Get full text

Use of a pharmacokinetic/pharmacodynamic approach in the cat to determine a dosage regimen for the COX-2 selective drug robenacoxib by GIRAUDEL, J.M, KING, J.N, JEUNESSE, E.C, LEES, P, TOUTAIN, P.-L

“…This study investigated the analgesic, anti-inflammatory and antipyretic efficacy of the new COX-2 selective inhibitor robenacoxib in the cat and established…”
Get full text

Differential inhibition of cyclooxygenase isoenzymes in the cat by the NSAID robenacoxib by GIRAUDEL, J.M, TOUTAIN, P.-L, KING, J.N, LEES, P

“…Robenacoxib is a new nonsteroidal anti-inflammatory drug (NSAID) developed for use in companion animal medicine. The objectives of this study were: to quantify…”
Get full text

Analgesic and anti-inflammatory actions of robenacoxib in acute joint inflammation in dog by SCHMID, V.B, SPRENG, D.E, SEEWALD, W, JUNG, M, LEES, P, KING, J.N

“…The objectives of this study were to establish dose-response and blood concentration-response relationships for robenacoxib, a novel nonsteroidal…”
Get full text

Removal of copper and iron prior to water hardness titration by Fritz, James S, King, Jefferey N

Get full text

Determination of the dosage of clomipramine for the treatment of urine spraying in cats by King, J.N, Steffan, J, Heath, S.E, Simpson, B.S, Crowell-Davis, S.L, Harrington, L.J.M, Weiss, A.B, Seewald, W

“…To determine the optimal dosage of clomipramine for the treatment of urine spraying in cats. Randomized controlled multicenter clinical trial. 67 neutered…”
Get full text

Genetic resistance of Sitka spruce (Picea sitchensis) populations to the white pine weevil (Pissodes strobi): distribution of resistance by King, J.N, Alfaro, R.I, Cartwright, C

“…Sitka spruce (Picea sitchensis) is highly susceptible to leader damage by the white pine weevil (Pissodes strobi). Population differences for resistance have…”
Get full text

Benazepril increases feed intake and body weight in healthy growing cats by King, J.N, Seewald, W, King, S, Goldenthal, E

Get full text