Search Results - "King, J. Darwin"

  • Showing 1 - 15 results of 15
Refine Results
  1. 1

    Activating AMP-activated protein kinase (AMPK) slows renal cystogenesis by Takiar, Vinita, Nishio, Saori, Seo-Mayer, Patricia, King, J. Darwin Jr, Li, Hui, Zhang, Li, Karihaloo, Anil, Hallows, Kenneth R, Somlo, Stefan, Caplan, Michael J

    “…Renal cyst development and expansion in autosomal dominant polycystic kidney disease (ADPKD) involves both fluid secretion and abnormal proliferation of…”
    Get full text
    Journal Article
  2. 2

    Noncanonical Control of Vasopressin Receptor Type 2 Signaling by Retromer and Arrestin by Feinstein, Timothy N., Yui, Naofumi, Webber, Matthew J., Wehbi, Vanessa L., Stevenson, Hilary P., King, J. Darwin, Hallows, Kenneth R., Brown, Dennis, Bouley, Richard, Vilardaga, Jean-Pierre

    Published in The Journal of biological chemistry (27-09-2013)
    “…The vasopressin type 2 receptor (V2R) is a critical G protein-coupled receptor (GPCR) for vertebrate physiology, including the balance of water and sodium…”
    Get full text
    Journal Article
  3. 3

    An Excess-Calcium-Binding-Site Model Predicts Neurotransmitter Release at the Neuromuscular Junction by Dittrich, Markus, Pattillo, John M., King, JDarwin, Cho, Soyoun, Stiles, Joel R., Meriney, Stephen D.

    Published in Biophysical journal (18-06-2013)
    “…Despite decades of intense experimental studies, we still lack a detailed understanding of synaptic function. Fortunately, using computational approaches, we…”
    Get full text
    Journal Article
  4. 4

    AMP-activated protein kinase phosphorylation of the R domain inhibits PKA stimulation of CFTR by King, Jr, J Darwin, Fitch, Adam C, Lee, Jeffrey K, McCane, Jill E, Mak, Don-On Daniel, Foskett, J Kevin, Hallows, Kenneth R

    “…The metabolic sensor AMP-activated protein kinase (AMPK) has emerged as an important link between cellular metabolic status and ion transport activity. We…”
    Get more information
    Journal Article
  5. 5

    AMPK agonists ameliorate sodium and fluid transport and inflammation in cystic fibrosis airway epithelial cells by Myerburg, Michael M, King, Jr, J Darwin, Oyster, Nicholas M, Fitch, Adam C, Magill, Amy, Baty, Catherine J, Watkins, Simon C, Kolls, Jay K, Pilewski, Joseph M, Hallows, Kenneth R

    “…The metabolic sensor AMP-activated kinase (AMPK) inhibits both the cystic fibrosis (CF) transmembrane conductance regulator (CFTR) Cl(-) channel and epithelial…”
    Get full text
    Journal Article
  6. 6

    Role of Binding and Nucleoside Diphosphate Kinase A in the Regulation of the Cystic Fibrosis Transmembrane Conductance Regulator by AMP-activated Protein Kinase by King, J Darwin, Lee, Jeffrey, Riemen, Claudia E., Neumann, Dietbert, Xiong, Sheng, Foskett, J.Kevin, Mehta, Anil, Muimo, Richmond, Hallows, Kenneth R.

    Published in The Journal of biological chemistry (28-09-2012)
    “…Cystic fibrosis transmembrane conductance regulator (CFTR) Cl− channel mutations cause cystic fibrosis lung disease. A better understanding of CFTR regulatory…”
    Get full text
    Journal Article
  7. 7

    CFTR regulation by phosphorylation by Alzamora, Rodrigo, King, Jr, J Darwin, Hallows, Kenneth R

    “…The cystic fibrosis transmembrane conductance regulator (CFTR) is the gene product mutated in cystic fibrosis, a common lethal genetic disease characterized by…”
    Get more information
    Journal Article
  8. 8

    Proportion of N-Type Calcium Current Activated by Action Potential Stimuli by King, J. Darwin, Jr, Meriney, Stephen D

    Published in Journal of neurophysiology (01-12-2005)
    “…Department of Neuroscience, University of Pittsburgh, Pittsburgh, Pennsylvania Submitted 16 December 2004; accepted in final form 10 August 2005 N-type calcium…”
    Get full text
    Journal Article
  9. 9

    Action potential gating of calcium channels and transmitter release by King, J Darwin

    Published 01-01-2007
    “…The regulation of transmitter release at the neuromuscular junction is tightly regulated by the influx of calcium in the presynaptic nerve terminal…”
    Get full text
    Dissertation
  10. 10

    Metabolic status changes the interregulation of AMPK and CFTR (893.26) by Hallows, Kenneth, King, J Darwin, Rush, Elizabeth, Xiong, Sheng, Li, Hui

    Published in The FASEB journal (01-04-2014)
    “…A better understanding of CFTR Cl‐ channel regulation could suggest new therapies for cystic fibrosis (CF). We previously found that the α1 catalytic subunit…”
    Get full text
    Journal Article
  11. 11

    Role of Binding and Nucleoside Diphosphate Kinase A (NDPK‐A) in the Regulation of CFTR by AMP‐Activated Protein Kinase (AMPK) by King, J Darwin, Lee, Jeffrey, Rieman, Claudia E., Mehta, Anil, Muimo, Richmond, Hallows, Kenneth R.

    Published in The FASEB journal (01-04-2012)
    “…Abstract only A better understanding of CFTR Cl − channel regulation could suggest new therapies for cystic fibrosis. AMPK binds to the CFTR C‐terminal tail,…”
    Get full text
    Journal Article
  12. 12
  13. 13

    AMPK Agonists Ameliorate Sodium and Fluid Transport and Inflammation in Cystic Fibrosis Airway Epithelial Cells by Myerburg, Michael M., King, J Darwin, Oyster, Nicholas M., Fitch, Adam C., Magill, Amy, Baty, Catherine J., Watkins, Simon C., Kolls, Jay K., Pilewski, Joseph M., Hallows, Kenneth R.

    “…The metabolic sensor AMP-activated kinase (AMPK) inhibits both the cystic fibrosis (CF) transmembrane conductance regulator (CFTR) Cl − channel and epithelial…”
    Get full text
    Journal Article
  14. 14

    Action potential gating of calcium channels and transmitter release by King, J. Darwin, Jr

    “…The regulation of transmitter release at the neuromuscular junction is tightly regulated by the influx of calcium in the presynaptic nerve terminal…”
    Get full text
    Dissertation
  15. 15