Search Results - "King, Alexia"

HOTAIRM1 lncRNA is downregulated in clear cell renal cell carcinoma and inhibits the hypoxia pathway by Hamilton, Michael J., Young, Matthew, Jang, Kay, Sauer, Silvia, Neang, Vanessa E., King, Alexia T., Girke, Thomas, Martinez, Ernest

“…HOXA Transcript Antisense RNA, Myeloid-Specific 1 (HOTAIRM1) is a conserved long non-coding RNA (lncRNA) involved in myeloid and neural differentiation that is…”
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Cross-species analysis identifies mitochondrial dysregulation as a functional consequence of the schizophrenia-associated 3q29 deletion by Purcell, Ryan H., Sefik, Esra, Werner, Erica, King, Alexia T., Mosley, Trenell J., Merritt-Garza, Megan E., Chopra, Pankaj, McEachin, Zachary T., Karne, Sridhar, Raj, Nisha, Vaglio, Brandon J., Sullivan, Dylan, Firestein, Bonnie L., Tilahun, Kedamawit, Robinette, Maxine I., Warren, Stephen T., Wen, Zhexing, Faundez, Victor, Sloan, Steven A., Bassell, Gary J., Mulle, Jennifer G.

“…The 1.6-megabase deletion at chromosome 3q29 (3q29Del) is the strongest identified genetic risk factor for schizophrenia, but the effects of this variant on…”
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Neural and metabolic dysregulation in PMM2-deficient human in vitro neural models by Radenkovic, Silvia, Budhraja, Rohit, Klein-Gunnewiek, Teun, King, Alexia Tyler, Bhatia, Tarun N., Ligezka, Anna N., Driesen, Karen, Shah, Rameen, Ghesquière, Bart, Pandey, Akhilesh, Kasri, Nael Nadif, Sloan, Steven A., Morava, Eva, Kozicz, Tamas

“…Phosphomannomutase 2-congenital disorder of glycosylation (PMM2-CDG) is a rare inborn error of metabolism caused by deficiency of the PMM2 enzyme, which leads…”
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Elucidating Mechanism of Ammonia Toxicity Using Cortical Organoids (P5-7.001) by Barton, Shawn, King, Alexia, Sing, Anson, Sampson, Maureen, Sloan, Steven

“…Abstract only…”
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3D Bioprinting of Neural Tissues by Cadena, Melissa, Ning, Liqun, King, Alexia, Hwang, Boeun, Jin, Linqi, Serpooshan, Vahid, Sloan, Steven A.

“…The human nervous system is a remarkably complex physiological network that is inherently challenging to study because of obstacles to acquiring primary…”
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TMIC-34. INFILTRATIVE BEHAVIOR OF PATIENT-DERIVED GLIOBLASTOMA CELL LINES IN REGION-SPECIFIC HUMAN BRAIN ORGANOIDS by Ganta, Saisrinidhi, Bhatia, Tarun, King, Alexia, Sing, Anson, Read, Renee, Sloan, Steven

“…Abstract Glioblastoma (GBM) is the most common malignant brain tumor in adults. GBMs are known for their highly invasive and proliferative properties and are…”
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TMIC-33. MICROENVIRONMENT-DRIVEN CHANGES IN GLIOBLASTOMA CELL STATE SIGNATURES EXAMINED USING REGION-SPECIFIC HUMAN BRAIN ORGANOIDS by Bhatia, Tarun, Ganta, Saisrinidhi, Sing, Anson, King, Alexia, Sojka, Caitlin, Hoang, Kimberly, Nduom, Edjah, Read, Renee, Olson, Jeffrey, Sloan, Steven

“…Abstract Cell state plasticity is retained by all stem-like and differentiated cells within glioblastoma (GBM) tumors. GBM cells can exploit these…”
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Identification of ligand–receptor pairs that drive human astrocyte development by Voss, Anna J., Lanjewar, Samantha N., Sampson, Maureen M., King, Alexia, Hill, Emily J., Sing, Anson, Sojka, Caitlin, Bhatia, Tarun N., Spangle, Jennifer M., Sloan, Steven A.

“…Extrinsic signaling between diverse cell types is crucial for nervous system development. Ligand binding is a key driver of developmental processes…”
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Three Dimensional Bioprinting of Neural Tissues by Cadena, Melissa, Ning, Liqun, King, Alexia, Hwang, Boeun, Jin, Linqi, Serpooshan, Vahid, Sloan, Steven A.

“…The human nervous system is a remarkably complex physiological network that is inherently challenging to study because of obstacles to acquiring primary…”
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Clinical trials-in-a-dish: Different inter-individual drug responses for calcium handling and electrophysiology in a cohort of hiPSC-derived cardiomyocytes by Fermini, Bernard, Sullivan, Denise D., Chal, Jerome, Fine, Eli J., Coyne, Shawn T., King, Alexia, Johnson, Jessica, Hernandez, Alexander Ulan, Obata, Chinye F., Coyne, Kevin P.

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Characterization of novel cell lines derived from a MYC‐driven murine model of lethal metastatic adenocarcinoma of the prostate by Markowski, Mark C., Hubbard, Gretchen K., Hicks, Jessica L., Zheng, Qizhi, King, Alexia, Esopi, David, Rege, Apurv, Yegnasubramanian, Srinivasan, Bieberich, Charles J., De Marzo, Angelo M.

“…Background: Loss or mutation of PTEN alleles at 10q23 in combination with 8q24 amplification (encompassing MYC) are common findings in aggressive, human…”
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