Search Results - "King, Aaron A"
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Unraveling the Transmission Ecology of Polio
Published in PLoS biology (01-06-2015)“…Sustained and coordinated vaccination efforts have brought polio eradication within reach. Anticipating the eradication of wild poliovirus (WPV) and the…”
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Detecting Adaptive Evolution in Phylogenetic Comparative Analysis Using the Ornstein-Uhlenbeck Model
Published in Systematic biology (01-11-2015)“…Phylogenetic comparative analysis is an approach to inferring evolutionary process from a combination of phylogenetic and phenotypic data. The last few years…”
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Phylogenetic Comparative Analysis: A Modeling Approach for Adaptive Evolution
Published in The American naturalist (01-12-2004)“…Biologists employ phylogenetic comparative methods to study adaptive evolution. However, none of the popular methods model selection directly. We explain and…”
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Inference for dynamic and latent variable models via iterated, perturbed Bayes maps
Published in Proceedings of the National Academy of Sciences - PNAS (20-01-2015)“…Iterated filtering algorithms are stochastic optimization procedures for latent variable models that recursively combine parameter perturbations with latent…”
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Plug-and-play inference for disease dynamics: measles in large and small populations as a case study
Published in Journal of the Royal Society interface (06-02-2010)“…methods require only simulations from a model and are thus free of such restrictions. We show the utility of the plug-and-play approach in the context of an…”
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Interactions between serotypes of dengue highlight epidemiological impact of cross-immunity
Published in Journal of the Royal Society interface (06-09-2013)“…Dengue, a mosquito-borne virus of humans, infects over 50 million people annually. Infection with any of the four dengue serotypes induces protective immunity…”
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Choices and trade-offs in inference with infectious disease models
Published in Epidemics (01-03-2020)“…•Conducting inference with mathematical models involve a choice of model, simulation method, inference method and software implementation.•We the criteria that…”
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Fine-scale heterogeneity in population density predicts wave dynamics in dengue epidemics
Published in Nature communications (22-02-2022)“…The spread of dengue and other arboviruses constitutes an expanding global health threat. The extensive heterogeneity in population distribution and potential…”
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Natural immune boosting in pertussis dynamics and the potential for long-term vaccine failure
Published in Proceedings of the National Academy of Sciences - PNAS (26-04-2011)“…Incidence of whooping cough, unlike many other childhood diseases for which there is an efficacious vaccine, has been increasing over the past twenty years…”
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Author Correction: Fine-scale heterogeneity in population density predicts wave dynamics in dengue epidemics
Published in Nature communications (11-03-2022)Get full text
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11
Differential and enhanced response to climate forcing in diarrheal disease due to rotavirus across a megacity of the developing world
Published in Proceedings of the National Academy of Sciences - PNAS (12-04-2016)“…The role of climate forcing in the population dynamics of infectious diseases has typically been revealed via retrospective analyses of incidence records…”
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Statistical inference for multi-pathogen systems
Published in PLoS computational biology (01-08-2011)“…There is growing interest in understanding the nature and consequences of interactions among infectious agents. Pathogen interactions can be operational at…”
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Time-varying, serotype-specific force of infection of dengue virus
Published in Proceedings of the National Academy of Sciences - PNAS (01-07-2014)“…Infectious disease models play a key role in public health planning. These models rely on accurate estimates of key transmission parameters such as the force…”
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14
Highly localized sensitivity to climate forcing drives endemic cholera in a megacity
Published in Proceedings of the National Academy of Sciences - PNAS (07-02-2012)“…The population dynamics of endemic cholera in urban environments—in particular interannual variation in the size and distribution of seasonal outbreaks—remain…”
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Interactions between Behavioral and Life‐History Trade‐Offs in the Evolution of Integrated Predator‐Defense Plasticity
Published in The American naturalist (01-09-2010)“…Inducible defense, which is phenotypic plasticity in traits that affect predation risk, is taxonomically widespread and has been shown to have important…”
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Immune boosting explains regime-shifts in prevaccine-era pertussis dynamics
Published in PloS one (26-08-2013)“…Understanding the biological mechanisms underlying episodic outbreaks of infectious diseases is one of mathematical epidemiology's major goals. Historic…”
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Epidemiological evidence for herd immunity induced by acellular pertussis vaccines
Published in Proceedings of the National Academy of Sciences - PNAS (18-02-2014)Get full text
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Cholera forecast for Dhaka, Bangladesh, with the 2015-2016 El Niño: Lessons learned
Published in PloS one (02-03-2017)“…A substantial body of work supports a teleconnection between the El Niño-Southern Oscillation (ENSO) and cholera incidence in Bangladesh. In particular, high…”
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Running for Your Life or Running for Your Dinner: What Drives Fiber‐Type Evolution in Lizard Locomotor Muscles?
Published in The American naturalist (01-05-2009)“…Despite its role in whole‐animal performance, the adaptation of muscle physiology related to terrestrial locomotion remains underexplored. We tested…”
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Statistical Inference for Partially Observed Markov Processes via the R Package pomp
Published in Journal of statistical software (01-03-2016)“…Partially observed Markov process (POMP) models, also known as hidden Markov models or state space models, are ubiquitous tools for time series analysis. The R…”
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