Search Results - "Kindsvogel, W"

A Soluble Class II Cytokine Receptor, IL-22RA2, is a Naturally Occurring IL-22 Antagonist by Xu, Wenfeng, Presnell, Scott R., Parrish-Novak, Julia, Kindsvogel, Wayne, Jaspers, Steve, Chen, Zhi, Dillon, Stacey R., Gao, Zeren, Gilbert, Teresa, Madden, Karen, Schlutsmeyer, Stacy, Yao, Lena, Whitmore, Theodore E., Chandrasekher, Yasmin, Grant, Francis J., Maurer, Mark, Jelinek, Laura, Storey, Harold, Brender, Ty, Hammond, Angie, Topouzis, Stavros, Clegg, Christopher H., Foster, Donald C.

“…IL-22 is an IL-10 homologue that binds to and signals through the class II cytokine receptor heterodimer IL-22RA1/CRF2-4. IL-22 is produced by T cells and…”
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A missense mutation in the glucagon receptor gene is associated with non-insulin-dependent diabetes mellitus by Hager, J, Hansen, L, Vaisse, C, Vionnet, N, Philippi, A, Poller, W, Velho, G, Carcassi, C, Contu, L, Julier, C, Cambien, F, Passa, P, Lathrop, M, Kindsvogel, W, Demenais, F, Nishimura, E, Froguel, P

“…Non-insulin-dependent diabetes mellitus (NIDDM) affects about 5% of the world population. The disease presents a polygenic mode of inheritance, but mechanisms…”
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The Gly40Ser mutation in the human glucagon receptor gene associated with NIDDM results in a receptor with reduced sensitivity to glucagon by Hansen, L. H., Abrahamsen, N., Hager, J., Jelinek, L., Kindsvogel, W., Froguel, P., Nishimura, E.

“…The Gly40Ser mutation in the human glucagon receptor gene associated with NIDDM results in a receptor with reduced sensitivity to glucagon. L H Hansen , N…”
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IL-28, IL-29 and their class II cytokine receptor IL-28R by Klucher, Kevin M, Sheppard, Paul, Kindsvogel, Wayne, Xu, Wenfeng, Henderson, Katherine, Schlutsmeyer, Stacy, Whitmore, Theodore E, Kuestner, Rolf, Garrigues, Ursula, Birks, Carl, Roraback, Jenny, Ostrander, Craig, Dong, Dennis, Shin, Jinu, Presnell, Scott, Fox, Brian, Haldeman, Betty, Cooper, Emily, Taft, David, Gilbert, Teresa, Grant, Francis J, Tackett, Monica, Krivan, William, McKnight, Gary, Clegg, Chris, Foster, Don

“…Cytokines play a critical role in modulating the innate and adaptive immune systems. Here, we have identified from the human genomic sequence a family of three…”
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Expression of BCMA, TACI, and BAFF-R in multiple myeloma: a mechanism for growth and survival by Novak, Anne J., Darce, Jaime R., Arendt, Bonnie K., Harder, Brandon, Henderson, Kathy, Kindsvogel, Wayne, Gross, Jane A., Greipp, Philip R., Jelinek, Diane F.

“…Multiple myeloma (MM) is a progressive disease that is thought to result from multiple genetic insults to the precursor plasma cell that ultimately affords the…”
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TACI and BCMA are receptors for a TNF homologue implicated in B-cell autoimmune disease by Gross, Jane A, Johnston, Janet, Mudri, Sherri, Enselman, Rachel, Dillon, Stacey R, Madden, Karen, Xu, Wenfeng, Parrish-Novak, Julia, Foster, Don, Lofton-Day, Cathy, Moore, Margaret, Littau, Alisa, Grossman, Angelika, Haugen, Harald, Foley, Kevin, Blumberg, Hal, Harrison, Kim, Kindsvogel, Wayne, Clegg, Christopher H

“…B cells are important in the development of autoimmune disorders by mechanisms involving disregulated polyclonal B-cell activation, production of pathogenic…”
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An islet-cell protein tyrosine phosphatase is a likely precursor to the 37-kDa autoantigen in type 1 diabetes: human and macaque sequences, tissue distribution, unique and shared epitopes, and predictive autoantibodies by LaGasse, J, Jelinek, L, Sexson, S, Lofton-Day, C, Breininger, J, Sheppard, P, Kindsvogel, W, Hagopian, W A

“…We sought to identify novel islet-cell autoantigens to better understand the pathogenesis, prediction, and immunotherapy of type 1 diabetes. Macaque and human…”
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Synergistic activation of the type I adenylyl cyclase by Ca2+ and Gs-coupled receptors in vivo by Wayman, G A, Impey, S, Wu, Z, Kindsvogel, W, Prichard, L, Storm, D R

“…The type I adenylyl cyclase is directly stimulated by Ca2+ and calmodulin in vivo (Choi, E. J., Wong, S. T., Hinds, T. R. and Storm, D. R. (1992) J. Biol…”
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Improved RNA sequencing method to determine immunoglobulin mRNA sequence by GRANT, F. J, LEVIN, S. D, GILBERT, T, KINDSVOGEL, W

“…An improved procedure was used to sequence the variable (V) regions of mRNA encoding a mouse monoclonal antibody, ML-05, which recognizes a melanoma tumor…”
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IL-21 enhances chemoimmunotherapy mediated death of chronic lymphocytic leukemia cells by Gowda, A. C., Ramanunni, A., Cheney, C., Roda, J., Kindsvogel, W., Henderson, D., pallavur, S., Carson, W., Muthusamy, N., Byrd, J. C.

“…Abstract only 7094 Chemoimmunotherapy with fludarabine and rituximab has demonstrated promising clinical activity in CLL. We hypothesized that the IL-21 might…”
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Expression Cloning and Signaling Properties of the Rat Glucagon Receptor by Jelinek, Laura J., Lok, Si, Rosenberg, Gary B., Smith, Robert A., Grant, Francis J., Biggs, Shaula, Bensch, Peggie A., Kuijper, Joseph L., Sheppard, Paul O., Sprecher, Cindy A., O'Hara, Patrick J., Foster, Don, Walker, Kathleen M., Lennie H. J. Chen, McKernan, Patricia A., Kindsvogel, Wayne

“…Glucagon and the glucagon receptor are a primary source of control over blood glucose concentrations and are especially important to studies of diabetes in…”
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IL-21 enhancement of rituximab-mediated B cell depletion by Hughes, S. D., Krejsa, C., Wagner, F., Heffernan, J., Henderson, K., Roque, R., Ponce, R., Kindsvogel, W., Sievers, E., Rogge, M.

“…Abstract only…”
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Characterization of a human-mouse chimeric antibody reactive with a human melanoma associated antigen by Marchitto, K S, Kindsvogel, W R, Beaumier, P L, Fine, S K, Gilbert, T, Levin, S D, Woodhouse, C S, Morgan, Jr, A C

“…The data presented demonstrate that a human-murine chimeric antibody has been generated that retains the immunoreactivity and has similar pharmacokinetic…”
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IL-21 enhances rituximab-mediated killing of B-lymphoma cell lines in vitro and in vivo by Kindsvogel, W., Hughes, S., Bannink, K., Heipel, M., Johnson, B., Holly, R., Sivakumar, P., Clegg, C., Sievers, E. L., Foster, D.

“…Abstract only…”
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IL-21 enhances rituximab-mediated killing of B-lymphoma cell lines in vitro and in vivo by Kindsvogel, W., Hughes, S., Bannink, K., Heipel, M., Johnson, B., Holly, R., Sivakumar, P., Clegg, C., Sievers, E. L., Foster, D.

“…Abstract only…”
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The human glucagon receptor encoding gene: structure, cDNA sequence and chromosomal localization by Lok, S, Kuijper, J L, Jelinek, L J, Kramer, J M, Whitmore, T E, Sprecher, C A, Mathewes, S, Grant, F J, Biggs, S H, Rosenberg, G B

“…Characterization of the human glucagon-receptor-encoding gene (GGR) should provide a greater understanding of blood glucose regulation and may reveal a genetic…”
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The Gly40Ser mutation in the human glucagon receptor gene associated with NIDDM results in a receptor with reduced sensitivity to glucagon by HANSEN, L. H, ABRAHAMSEN, N, HAGER, J, JELINEK, L, KINDSVOGEL, W, FROGUEL, P, NISHIMURA, E

“…The pancreatic islet hormone, glucagon, stimulates hepatic glucose production and has also been shown to potentiate glucose-induced insulin secretion. Because…”
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Glucagon-mediated Ca2+ signaling in BHK cells expressing cloned human glucagon receptors by Hansen, L H, Gromada, J, Bouchelouche, P, Whitmore, T, Jelinek, L, Kindsvogel, W, Nishimura, E

“…From video imaging of fura 2-loaded baby hamster kidney (BHK) cells stably expressing the cloned human glucagon receptor, we found the Ca2+ response to…”
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An evaluation of the potential to use tumor-associated antigens as targets for antitumor T cell therapy using transgenic mice expressing a retroviral tumor antigen in normal lymphoid tissues by JIAN HU, KINDSVOGEL, W, BUSBY, S, BAILEY, M. C, YUAN-YUAN SHI, GREENBERG, P. D

“…A major obstacle to the development of T cell therapy for the treatment of human tumors has been the difficulty generating T cells specifically reactive with…”
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A cloned cDNA probe for rat immunoglobulin epsilon heavy chain: construction, identification, and DNA sequence by Kindsvogel, W R, Reddy, E P, Moore, J M, Faust, Jr, C H

“…IgE has clinical importance because it is responsible for immediate hypersensitivity. Studies of IgE expression in rats appear to contradict current models for…”
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