Search Results - "Kindrat, Iryna"

MicroRNA-152-mediated dysregulation of hepatic transferrin receptor 1 in liver carcinogenesis by Kindrat, Iryna, Tryndyak, Volodymyr, de Conti, Aline, Shpyleva, Svitlana, Mudalige, Thilak K, Kobets, Tetyana, Erstenyuk, Anna M, Beland, Frederick A, Pogribny, Igor P

“…Over-expression of transferrin receptor 1 (TFRC) is observed in hepatocellular carcinoma (HCC); however, there is a lack of conclusive information regarding…”
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Effect of methapyrilene hydrochloride on hepatic intracellular iron metabolism in vivo and in vitro by Kindrat, Iryna, Dreval, Kostiantyn, Shpyleva, Svitlana, Tryndyak, Volodymyr, de Conti, Aline, Mudalige, Thilak K., Chen, Tao, Erstenyuk, Anna M., Beland, Frederick A., Pogribny, Igor P.

“…•Methapyrilene altered the expression of classic hepatoxicity marker genes in vivo and in vitro.•Methapyrilene inhibited the expression of the hepatic…”
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Effect of aflatoxin B1, benzo[a]pyrene, and methapyrilene on transcriptomic and epigenetic alterations in human liver HepaRG cells by Tryndyak, Volodymyr, Kindrat, Iryna, Dreval, Kostiantyn, Churchwell, Mona I., Beland, Frederick A., Pogribny, Igor P.

“…The increasing number of man-made chemicals in the environment that may pose a carcinogenic risk highlights the need for developing reliable time- and…”
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Effect of aflatoxin B 1 , benzo[a]pyrene, and methapyrilene on transcriptomic and epigenetic alterations in human liver HepaRG cells by Tryndyak, Volodymyr, Kindrat, Iryna, Dreval, Kostiantyn, Churchwell, Mona I, Beland, Frederick A, Pogribny, Igor P

“…The increasing number of man-made chemicals in the environment that may pose a carcinogenic risk highlights the need for developing reliable time- and…”
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Aspirin as a Potential Geroprotector: Experimental Data and Clinical Evidence by Lushchak, Oleh, Piskovatska, Veronika, Strilbytska, Olha, Kindrat, Iryna, Stefanyshyn, Nadya, Koliada, Alexander, Bubalo, Volodymyr, Storey, Kenneth B, Vaiserman, Alexander

“…Aging is a biological process with effects at the molecular, cellular, tissue, organ, system, and organismal levels and is characterized by decline in physical…”
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Abstract 5887: A microRNA signature panel predicts differential sensitivity of liver cancer cells to chemotherapeutic drugs by Tryndyak, Volodymyr, Kindrat, Iryna, McDannell, Brigit, Beland, Frederick A., Pogribny, Igor P.

“…Hepatocellular carcinoma (HCC) is one of the deadliest human cancers, with a steadily rising incidence in the United States and worldwide. Most HCC patients…”
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Epigenetically mediated inhibition of S‐adenosylhomocysteine hydrolase and the associated dysregulation of 1‐carbon metabolism in nonalcoholic steatohepatitis and hepatocellular carcinoma by Pogribny, Igor P., Dreval, Kostiantyn, Kindrat, Iryna, Melnyk, Stepan, Jimenez, Leandro, Conti, Aline, Tryndyak, Volodymyr, Pogribna, Marta, Ortega, Juliana Festa, James, S. Jill, Rusyn, Ivan, Beland, Frederick A.

“…The substantial rise in the prevalence of nonalcoholic steatohepatitis (NASH), an advanced form of nonalcoholic fatty liver disease, and the strong association…”
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Cellular and Molecular Effects of Prolonged Low-Level Sodium Arsenite Exposure on Human Hepatic HepaRG Cells by Dreval, Kostiantyn, Tryndyak, Volodymyr, Kindrat, Iryna, Twaddle, Nathan C, Orisakwe, Orish Ebere, Mudalige, Thilak K, Beland, Frederick A, Doerge, Daniel R, Pogribny, Igor P

“…Abstract Inorganic arsenic is a human carcinogen associated with several types of cancers, including liver cancer. Inorganic arsenic has been postulated to…”
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Abstract 920: Mechanism of the transferrin receptor 1 dysregulation in hepatocarcinogenesis by Kindrat, Iryna, Tryndyak, Volodymyr, de Conti, Aline, Shpyleva, Svitlana, Erstenyuk, Anna, Beland, Frederick A., Pogribny, Igor

“…Hepatocellular carcinoma (HCC) is one of the most prevalent life-threatening human cancers, with a rapidly increasing incidence worldwide. The pathogenesis of…”
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Organ-specific epigenetic changes induced by the non-genotoxic liver carcinogen methapyrilene in Fischer 344 rats by Shpyleva, Svitlana, Dreval, Kostiantyn, de Conti, Aline, Kindrat, Iryna, Melnyk, Stepan, Yan, Jian, Chen, Tao, Beland, Frederick A., Pogribny, Igor P.

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Editor's Highlight: Organ-Specific Epigenetic Changes Induced by the Nongenotoxic Liver Carcinogen Methapyrilene in Fischer 344 Rats by Shpyleva, Svitlana, Dreval, Kostiantyn, de Conti, Aline, Kindrat, Iryna, Melnyk, Stepan, Yan, Jian, Chen, Tao, Beland, Frederick A, Pogribny, Igor P

“…Continuous lifetime exposure to certain natural and man-made chemicals is a major cause of cancers in humans; therefore, evaluating the carcinogenic risks of…”
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