Search Results - "Kindler, H"

A randomized, placebo-controlled phase 2 study of ganitumab (AMG 479) or conatumumab (AMG 655) in combination with gemcitabine in patients with metastatic pancreatic cancer by Kindler, H.L., Richards, D.A., Garbo, L.E., Garon, E.B., Stephenson, J.J., Rocha-Lima, C.M., Safran, H., Chan, D., Kocs, D.M., Galimi, F., McGreivy, J., Bray, S.L., Hei, Y., Feigal, E.G., Loh, E., Fuchs, C.S.

“…We evaluated the efficacy and safety of ganitumab (a mAb antagonist of insulin-like growth factor 1 receptor) or conatumumab (a mAb agonist of human death…”
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Screening for risk of child abuse and neglect. A practicable method? by Kindler, H

“…Selective primary prevention programs for child abuse and neglect depend on risk screening instruments that have the goal of systematically identifying…”
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A phase III trial of pemetrexed plus gemcitabine versus gemcitabine in patients with unresectable or metastatic pancreatic cancer by Oettle, H., Richards, D., Ramanathan, R. K., van Laethem, J. L., Peeters, M., Fuchs, M., Zimmermann, A., John, W., Von Hoff, D., Arning, M., Kindler, H. L.

“…Background: This randomized phase III study compared the overall survival (OS) of pemetrexed plus gemcitabine (PG) versus standard gemcitabine (G) in patients…”
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A phase II study of a human anti-PDGFRα monoclonal antibody (olaratumab, IMC-3G3) in previously treated patients with metastatic gastrointestinal stromal tumors by Wagner, A.J., Kindler, H., Gelderblom, H., Schöffski, P., Bauer, S., Hohenberger, P., Kopp, H.-G., Lopez-Martin, J.A., Peeters, M., Reichardt, P., Qin, A., Nippgen, J., Ilaria, R.L., Rutkowski, P.

“…This study evaluated tumor response to olaratumab (an anti-PDGFRα monoclonal antibody) in previously treated patients with metastatic gastrointestinal stromal…”
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Predicted vitamin D status and colon cancer recurrence and mortality in CALGB 89803 (Alliance) by Fuchs, M.A., Yuan, C., Sato, K., Niedzwiecki, D., Ye, X., Saltz, L.B., Mayer, R.J., Mowat, R.B., Whittom, R., Hantel, A., Benson, A., Atienza, D., Messino, M., Kindler, H., Venook, A., Innocenti, F., Warren, R.S., Bertagnolli, M.M., Ogino, S., Giovannucci, E.L., Horvath, E., Meyerhardt, J.A., Ng, K.

“…Observational studies suggest that higher levels of 25-hydroxyvitamin D3 (25(OH)D) are associated with a reduced risk of colorectal cancer and improved…”
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The visual analog scale allows effective measurement of preoperative Anxiety and detection of patients' anesthetic concerns by KINDLER, C. H, HARMS, C, AMSLER, F, IHDE-SCHOLL, T, SCHEIDEGGER, D

“…The advent of managed care, reduction of costs, and advances in medical technology place increasing demands on anesthesiologists. Preoperative anxiety may go…”
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Disease volumes as a marker for patient response in malignant pleural mesothelioma by Labby, Z.E., Nowak, A.K., Dignam, J.J., Straus, C., Kindler, H.L., Armato, S.G.

“…The goal of this study was to create a comprehensive model for malignant pleural mesothelioma patient survival utilizing continuous, time-varying estimates of…”
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Citation Classics in Anesthetic Journals by Baltussen, Anja, Kindler, Christoph H.

“…The number of citations an article receives after its publication reflects its recognition in the scientific community. In the present study, therefore, we…”
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Citation classics in critical care medicine by BALTUSSEN, Anja, KINDLER, Christoph H

“…The number of citations an article receives after its publication reflects its impact on the scientific community. Our purpose was to identify and examine the…”
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Olaparib as maintenance treatment following first-line platinum-based chemotherapy in patients with a germline BRCA mutation and metastatic pancreatic cancer: phase III POLO trial by Golan, T., Hammel, P., Reni, M., Van Cutsem, E., Macarulla, T., Hall, M., Park, J., Hochhauser, D., Arnold, D., Oh, D., Reinacher-Schick, A., Tortora, G., Algül, H., O’Reilly, E., McGuinness, D., Cui, K., Schlienger, K., Locker, G., Kindler, H.

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Randomized phase II trial of pemetrexed/cisplatin with or without CBP501 in patients with advanced malignant pleural mesothelioma by Krug, L.M, Wozniak, A.J, Kindler, H.L, Feld, R, Koczywas, M, Morero, J.L, Rodriguez, C.P, Ross, H.J, Bauman, J.E, Orlov, S.V, Ruckdeschel, J.C, Mita, A.C, Fein, L, He, X, Hall, R, Kawabe, T, Sharma, S

“…Highlights • CBP501 enhances cisplatin cytotoxicity and blocks DNA repair at the G2 checkpoint. • Patients with pleural mesothelioma received…”
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Countering posttraumatic LHPA activation in refugee mothers and their infants by Ullmann, E, Bornstein, S R, Lanzman, R S, Kirschbaum, C, Sierau, S, Doehnert, M, Zimmermann, P, Kindler, H, Schauer, M, Ruf-Leuschner, M, Fegert, J M, von Klitzing, K, Ziegenhain, U

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Postoperative patient complaints: a prospective interview study of 12,276 patients by Lehmann, Michael, MD, Monte, Kai, CRNA, Barach, Paul, MD, MPH, Kindler, Christoph H., MD

“…Abstract Study Objective To evaluate the incidence of perioperative minor adverse events and to analyze patient satisfaction based on potential explanatory…”
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Phase II study of flavopiridol in patients with advanced colorectal cancer by Aklilu, M., Kindler, H. L., Donehower, R. C., Mani, S., Vokes, E. E.

“…Background: Flavopiridol, a synthetic flavone that inhibits cell cycle progression, has demonstrated activity in colon cancer in xenografts and in a phase I…”
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A genetic analysis of gemcitabine-induced high-grade neutropenia in pancreatic cancer patients by Innocenti, F., Jiang, C., Sibley, A.B., Denning, S., Etheridge, A.S., Watson, D., Niedzwiecki, D., Hatch, A.J., Hurwitz, H., Nixon, A., Furukawa, Y., Kubo, M., Crona, D.J., Kindler, H., McLeod, H.L., Ratain, M.J., Owzar, K.

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Risikoscreening als systematischer Zugang zu Frühen Hilfen: Ein gangbarer Weg? by Kindler, H.

“…Zusammenfassung Verfahren des Risikoscreenings verfolgen das Ziel, unter Bedingungen von Freiwilligkeit möglichst systematisch Familien zu identifizieren, die…”
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Coronary microvascular dysfunction in male patients with Anderson-Fabry disease and the effect of treatment with α galactosidase A by Elliott, P M, Kindler, H, Shah, J S, Sachdev, B, Rimoldi, O E, Thaman, R, Tome, M T, McKenna, W J, Lee, P, Camici, P G

“…Objective: To measure coronary flow reserve (CFR), an index of microvascular function, in Anderson-Fabry disease (AFD) at baseline and after enzyme replacement…”
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Doxycycline for the treatment of paronychia induced by the epidermal growth factor receptor inhibitor cetuximab by Suh, K-Y., Kindler, H.L., Medenica, M., Lacouture, M.

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A phase I study of the oral combination of CI-994, a putative histone deacetylase inhibitor, and capecitabine by Undevia, S. D., Kindler, H. L., Janisch, L., Olson, S. C., Schilsky, R. L., Vogelzang, N. J., Kimmel, K. A., Macek, T. A., Ratain, M. J.

“…Background: This study was conducted to determine the toxicity profile, maximum tolerated dose (MTD) and pharmacokinetics of the putative histone deacetylase…”
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Small-Dose Intrathecal Clonidine and Isobaric Bupivacaine for Orthopedic Surgery: A Dose-Response Study by Strebel, Stephan, Gurzeler, Jürg A., Schneider, Markus C., Aeschbach, Armin, Kindler, Christoph H.

“…We examined the dose-response relationship of intrathecal clonidine at small doses (≤150 μg) with respect to prolonging bupivacaine spinal anesthesia. We aimed…”
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