Search Results - "Kinch, M S"

EphA2 overexpression causes tumorigenesis of mammary epithelial cells by ZELINSKI, Daniel P, ZANTEK, Nicole Dodge, STEWART, Jane C, IRIZARRY, Armando R, KINCH, Michael S

“…Elevated levels of protein tyrosine phosphorylation contribute to a malignant phenotype, although the tyrosine kinases that are responsible for this signaling…”
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Overexpression of the EphA2 tyrosine kinase in prostate cancer by Walker-Daniels, J., Coffman, K., Azimi, M., Rhim, J.S., Bostwick, D.G., Snyder, P., Kerns, B.J., Waters, D.J., Kinch, M.S.

“…BACKGROUND Molecules that are highly expressed by human prostate cancers may serve as therapeutically relevant targets or tumor markers. Tyrosine kinases are…”
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Activation of Rac1, RhoA, and mitogen-activated protein kinases is required for Ras transformation by Khosravi-Far, Roya, Solski, Patricia A., Clark, Geoffrey J., Kinch, Michael S., Der, Channing J.

“…Article Usage Stats Services MCB Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley…”
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Integrin-mediated cell adhesion activates mitogen-activated protein kinases by Chen, Q, Kinch, M S, Lin, T H, Burridge, K, Juliano, R L

“…Integrins can function as signal-transducing receptors capable of modulating cell growth and gene expression (Juliano, R. L., and Haskill, S. (1993) J. Cell…”
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Tyrosine Phosphorylation Regulates the Adhesions of Ras-Transformed Breast Epithelia by Kinch, Michael S., Clark, Geoffrey J., Der, Channing J., Burridge, Keith

“…Transformed epithelial cells often are characterized by a fibroblastic or mesenchymal morphology. These cells exhibit altered cell-cell and cell-substrate…”
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TEL, a Putative Tumor Suppressor, Modulates Cell Growth and Cell Morphology of Ras-Transformed Cells While Repressing the Transcription of stromelysin-1 by Fenrick, Randy, Wang, Lilin, Nip, John, Amann, Joseph M., Rooney, Robert J., Walker-Daniels, Jennifer, Crawford, Howard C., Hulboy, Diana L., Kinch, Michael S., Matrisian, Lynn M., Hiebert, Scott W.

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The human antiporcine cellular repertoire. In vitro studies of acquired and innate cellular responsiveness by Kirk, A D, Li, R A, Kinch, M S, Abernethy, K A, Doyle, C, Bollinger, R R

“…Discordant xenogeneic transplantation offers a potentially unlimited source of donor organs from easily bred, nonendangered, physiologically compatible…”
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Molecular regulation of tumor cell vasculogenic mimicry by tyrosine phosphorylation : Role of epithelial cell kinase (Eck/EphA2) by HESS, Angela R, SEFTOR, Elisabeth A, GARDNER, Lynn M. G, CARLES-KINCH, Kelly, SCHNEIDER, Galen B, SEFTOR, Richard E. B, KINCH, Michael S, HENDRIX, Mary J. C

“…During embryogenesis, blood vessels are formed initially by the process of vasculogenesis, the in situ differentiation of mesenchymal cells into endothelial…”
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Altered adhesions in ras-transformed breast epithelial cells by Kinch, M S, Burridge, K

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Cell adhesion mediated by CD4 and MHC class II proteins requires active cellular processes by Kinch, MS, Strominger, JL, Doyle, C

“…Human CD4 is an accessory molecule found on the cell surface of a subset of T lymphocytes. We have previously shown by infection of simian fibroblasts with an…”
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Rho-stimulated contractility contributes to the fibroblastic phenotype of Ras-transformed epithelial cells by Zhong, C, Kinch, M S, Burridge, K

“…Oncogenic transformation of cells alters their morphology, cytoskeletal organization, and adhesive interactions. When the mammary epithelial cell line MCF10A…”
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Workgroup 2: Human xenograft models of prostate cancer by Stearns, Mark E., Ware, Joy L., Agus, David B., Chang, Ching-Jer, Fidler, Isaiah J., Fife, Rose S., Goode, Robin, Holmes, Eric, Kinch, Michael S., Peehl, Donna M., Pretlow II II, Thomas G., Thalmann, George N.

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Predicting the sites of metastases from lung cancer using molecular biologic markers by D’Amico, Thomas A, Aloia, Thomas A, Moore, Mary-Beth H, Conlon, Debbi H, Herndon, James E, Kinch, Michael S, Harpole, David H

“…Background. The use of molecular markers in staging non-small cell lung cancer (NSCLC) has been supported in retrospective prognostic models but has not been…”
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The Ras-related Protein Rheb Is Farnesylated and Antagonizes Ras Signaling and Transformation by Clark, Geoffrey J., Kinch, Michael S., Rogers-Graham, Kelley, Sebti, Said M., Hamilton, Andrew D., Der, Channing J.

“…Presently, nothing is known about the function of the Ras-related protein Rheb. Since Rheb shares significant sequence identity with the core effector domains…”
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E-cadherin regulates the function of the Epha2 receptor tyrosine kinase by ZANTEK, N. D, AZIMI, M, FEDOR-CHAIKEN, M, BINGCHENG WANG, BRACKENBURY, R, KINCH, M. S

“…EphA2 is a member of the Eph family of receptor tyrosine kinases, which are increasingly understood to play critical roles in disease and development. We…”
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MCF-10A-NeoST : A new cell system for studying cell-ECM and cell-cell interactions in breast cancer by ZANTEK, Nicole Dodge, WALKER-DANIELS, Jennifer, STEWART, Jane, HANSEN, Rhonda K, ROBINSON, Daniel, HUI MIAO, BINGCHENG WANG, KUNG, Hsing-Jien, BISSELL, Mina J, KINCH, Michael S

“…There is a continuing need for genetically matched cell systems to model cellular behaviors that are frequently observed in aggressive breast cancers. We…”
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Overexpression of the Ras-related TC21/R-Ras2 protein may contribute to the development of human breast cancers by Clark, G J, Kinch, M S, Gilmer, T M, Burridge, K, Der, C J

“…Although experimental studies suggest that aberrant Ras function can promote the malignant progression of human breast epithelial cells, the occurrence of…”
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Cytometric analysis of cell contact and adhesion by Kinch, M S

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Identification of tyrosine phosphorylated adhesion proteins in human cancer cells by Kinch, M S, Kilpatrick, K E, Zhong, C

“…Tyrosine phosphorylation is a form of signal transduction that regulates cell growth, differentiation, migration, and survival. This knowledge has promoted…”
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Interactions of CD4 with MHC Class II Molecules, T Cell Receptors and p56lck by Dario A. A. Vignali, Doyle, Carolyn, Kinch, Michael S., Shin, Jaekyoon, Strominger, Jack L.

“…CD4 and CD8 are members of the immunoglobulin supergene family of proteins, and function as coreceptors with the T cell receptor (TCR) in binding MHC class II…”
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