Search Results - "Kimura, Ninako"
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Regulation of Primary Metabolic Pathways in Oyster Mushroom Mycelia Induced by Blue Light Stimulation: Accumulation of Shikimic Acid
Published in Scientific reports (27-02-2015)“…Shikimic acid is a key intermediate in the aromatic amino acid pathway as well as an important starting material for the synthesis of Tamiflu , a potent and…”
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Structure-activity relationship for the folding intermediate-selective inhibition of DYRK1A
Published in European journal of medicinal chemistry (05-01-2022)“…DYRK1A phosphorylates proteins involved in neurological disorders in an intermolecular manner. Meanwhile, during the protein folding process of DYRK1A, a…”
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DnaK promotes autophosphorylation of DYRK1A and its family kinases in Escherichia coli-based cell-free protein expression
Published in Biochemical and biophysical research communications (25-12-2023)“…Dual-specificity tyrosine phosphorylation-regulated kinase 1A (DYRK1A) is one of the drug target kinases involved in neurological disorders. DYRK1A…”
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Expression and purification of DYRK1A kinase domain in complex with its folding intermediate-selective inhibitor FINDY
Published in Protein expression and purification (01-08-2022)“…The kinase DYRK1A phosphorylates substrate proteins that are involved in the progression of many diseases. DYRK1A also phosphorylates its own residues on key…”
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