Search Results - "Kimmel, Edgar C."

PERFORMANCE, FLUID MECHANICS, AND DESIGN OF A SMALL-ANIMAL, WHOLE-BODY INHALATION EXPOSURE CHAMBER by Kimmel, Edgar C, Yerkes, Kirk L, Carpenter, Robert L

“…A 0.7-m3 inhalation exposure chamber was designed for continuous whole-body exposure of up to 64 small laboratory rodents to a variety of airborne toxicants…”
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Lung function and airway inflammation in rats following exposure to combustion products of carbon–graphite/epoxy composite material: comparison to a rodent model of acute lung injury by Whitehead, Gregory S, Grasman, Keith A, Kimmel, Edgar C

“…Pulmonary function and inflammation in the lungs of rodents exposed by inhalation to carbon/graphite/epoxy advanced composite material (ACM) combustion…”
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PRELIMINARY ASSESSMENT OF A PYROTECHNICALLY GENERATED AEROSOL FIRE SUPPRESSANT by Smith, Eldon A, Kimmel, Edgar C, Bowen, Larry E, Reboulet, James E, Carpenter, Robert L

“…Fischer 344 rats (approximately 250-300 g) were exposed to the aerosol resulting from the pyrolysis of SFE Formulation A at a loading of 50 or 80 g/ m3…”
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PHYSIOLOGIC MODELS FOR COMPARISON OF INHALATION DOSE BETWEEN LABORATORY AND FIELD-GENERATED ATMOSPHERES OF A DRY POWDER FIRE SUPPRESSANT by Kimmel, C. Kimmel, Carpenter, L. Carpenter, Smith, A. Smith, Reboulet, E. Reboulet, Black, H. Black

“…SFE, a solid (dry powder) fire extinguishant, has been evaluated for fire suppression. A fire suppression atmosphere is achieved from pyrolysis of solid SFE,…”
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A BASIC COMPUTER PROGRAM FOR RAPID STANDARD GAS BAG CALCULATIONS by E. Reboulet, James, C. Kimmel, Edgar, L. Carpenter, Robert

“…The preparation of standard gas bags containing known volumes of toxicant and diluting gas is commonly used for the calibration of analytical instrumentation…”
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Chromate Concentration Bias in Primer Paint Particles by LaPuma, Peter T., Fox, Joseph M., Kimmel, Edgar C.

“…Chromate-containing primer paints are used to prevent corrosion on metal surfaces. Chromate contains hexavalent chromium (Cr 6+), a human carcinogen. The…”
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A physiological model for predicting carboxyhemoglobin formation from exposure to carbon monoxide in rats by Kimmel, Edgar C, Carpenter, Robert L, Reboulet, James E, Still, Kenneth R

“…1  Geo-Centers, Inc., and 2  Naval Health Research Center Detachment Toxicology, Wright-Patterson Air Force Base, Ohio 45433-7903 A time-dependent simulation…”
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Airway reactivity response to aged carbon-graphite/epoxy composite material smoke by Kimmel, Edgar C., Reboulet, James E., Courson, David L., Still, Kenneth R.

“…Exposure of na& uml;ve guinea pigs for a total of 30 min to aged smoke from pyrolysis of 5, 10 and 100 g of carbon–graphite/epoxy‐advanced composite material…”
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A typical path model of tracheobronchial clearance of inhaled particles in rats by Kimmel, Edgar C, Reboulet, James E, Carpenter, Robert L

“…A mathematical description of particle clearance from the ciliated conducting airways (tracheobronchial region) of the lungs in rats was developed, assuming…”
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Characterization of particulate matter in carbon-graphite/epoxy advanced composite material smoke by Kimmel, Edgar C, Courson, David L

“…The physical and chemical properties of the particulate fraction of carbon-graphite/epoxy advanced composite material (cgeACM) smoke were measured to address…”
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Carbon dioxide accumulation during small animal, whole body plethysmography: effects on ventilation, indices of airway function, and aerosol deposition by Kimmel, Edgar C, Whitehead, Gregory S, Reboulet, James E, Carpenter, Robert L

“…Barometric (whole body) plethysmography is used to examine changes in ventilation and breathing pattern in unrestrained animals during exposure to therapeutic…”
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Effects of a 13-week chloropentafluorobenzene inhalation exposure of Fischer 344 rats and B6C3F1 mice by Kinkead, E R, Bunger, S K, Kimmel, E C, Flemming, C D, Wall, H G, Grabau, J H

“…Chloropentafluorobenzene (CPFB) has been identified as a candidate simulant for nonpersistent chemical warfare agents. Acute toxicity studies have shown that…”
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Calculation of exposure chamber leak rate with thermal correction: a measure of chamber integrity by Kimmel, E C, Reboulet, J E

“…A method for assessing inhalation exposure chamber integrity by calculation of leak rate was modified to account for temporal changes of temperature in the…”
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Acute Lung Injury, Acute Respiratory Distress Syndrome and Inhalation Injury: An Overview by Kimmel, Edgar C., Still, Kenneth R.

“…ABSTRACT Acute Lung Injury (ALI) and the Acute Respiratory Distress Syndrome (ARDS) are severe respiratory diseases that have a very poor prognosis and have…”
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A SMALL ANIMAL PLETHYSMOGRAPH/EXPOSURE TUBE FOR DETERMINATION OF RESPIRATORY MECHANICS DURING EXPOSURE, USING A NONINVASIVE METHOD TO MEASURE INTRAPLEURAL PRESSURE by Kimmel, Edgar C.

“…The real-time measurement of changes in respiratory mechanics, primarily dynamic compliance (C dyn) and airway resistance (R L) , is often used to assess the…”
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A Simple, Inexpensive Solid Fuel Furnace for Small Scale Combustion Toxicity Studies by Reboulet, James E., Kimmel, Edgar C.

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Evaluation of the Respiratory Tract after Acute Exposure to a Pyrotechnically Generated Aerosol Fire Suppressant by Smith, Eldon A., Kimmel, Edgar C., English, Jeffrey H, Bowen, Larry E., Reboulet, James E., Carpenter, Robert L.

“…Fischer 344 rats (250–300 g) were exposed to the resulting aerosols from the pyrolysis of Spectrex Fire Extinguishant (SFE) Formulation A, a pyrotechnically…”
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Pulmonary mechanical, ventilatory, and gas exchange abnormalities in rats with monocrotaline-induced pulmonary hypertension by Gillespie, M N, Frederick, W B, Altiere, R J, Olson, J W, Kimmel, E C

“…Recent clinical studies have suggested that peripheral airways dysfunction contributes to the pathogenesis of idiopathic pulmonary hypertension. To determine…”
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Augmentation of elastase-induced emphysema by cigarette smoke. Effects of reduced nicotine content by Diamond, L, Kimmel, E C, Lai, Y L, Winsett, D W

“…To examine the role of nicotine in the augmentation of elastase-induced emphysema by cigarette smoke, animals that had been pretreated with porcine pancreatic…”
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