Search Results - "Kimler, BF"

Abstract P3-10-02: Differential response of inflammatory cytokines to omega-3 fatty acid supplementation based on menopausal status by Kimler, BF, Fabian, CJ

“…Abstract Background: High dose marine omega-3 fatty acid supplementation is currently undergoing assessment in early phase primary prevention trials. A…”
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Abstract P2-08-16: Impact of germline BRCA mutation status on survival in women with metastatic triple negative breast cancer by Larson, K, Wang, YY, Finke, K, O'Dea, AP, Khan, Q, Nye, L, Heldstab, J, Godwin, AK, Kimler, BF, Sharma, P

“…Abstract Background: 15-20% of patients with triple negative breast cancer (TNBC) harbor deleterious germline (g) BRCA1/2 mutations. Recent data suggests that…”
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Abstract P3-13-04: Change in oncotype DX variables and Ki67 response and outcome in women with ER positive early breast cancer treated with neo-adjuvant anastrozole and fulvestrant by Khan, QJ, Fabian, CJ, Kimler, BF, O'Dea, AP, Mamen, J, Amin, A, Wagner, J, Springer, M, Baccaray, S, Sharma, P

“…Abstract Neo-adjuvant endocrine therapy (NAET) provides opportunity for on-treatment assessment of endocrine responsiveness and need for adjuvant chemotherapy…”
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Abstract P2-05-28: The impact of the plant lignin secoisolariciresinol diglycoside on preclinical models of estrogen receptor positive breast cancer by Bowers, LW, Ford, NA, Rossi, EL, Shamsunder, MG, Kimler, BF, Fabian, CJ, Hursting, SD

“…Abstract Background: Several preclinical studies indicate that secoisolariciresinol diglycoside (SDG), a polyphenolic plant lignin found most abundantly in…”
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Abstract P4-13-03: Changes in the gut microbiome of post-menopausal women 2 weeks after initiating a structured weight loss intervention by Fabian, CJ, Kimler, BF, Umar, S, Ahmed, I, Befort, CA, Nydegger, JL, Kreutzjans, AL, Powers, KR, Klemp, JR, Spaeth, KR, Sullivan, DK

“…Abstract Background Change in the relative composition of the gut microbiome at the phyla level, particularly decreases in Bacteroidetes and increases in…”
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Abstract P6-12-11: Feasibility and biomarker modulation due to high levels of moderate to vigorous physical activity as part of a weight loss intervention in older, sedentary, obese breast cancer survivors by Fabian, CJ, Klemp, JR, Burns, JM, Vidoni, ED, Nydegger, JL, Kreutzjans, AL, Phillips, TL, Baker, HA, Hendry, B, John, C, Amin, AL, Khan, QJ, Mitchell, MP, O'Dea, AP, Sharma, P, Wagner, JL, Hursting, SD, Kimler, BF

“…Abstract We sought to demonstrate that older, sedentary, obese breast cancer survivors could achieve > 200 minutes per week of moderate to vigorous physical…”
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Abstract P4-10-06: Influence of older age on triple negative breast cancer (TNBC) clinical-pathological characteristics and outcomes by Mina, A, Lehn, C, Wang, YY, Klemp, JR, O'Dea, AP, Elia, M, Hoffmann, M, Crane, G, Sheehan, M, Madhusudhana, S, Jensen, RA, Godwin, AK, Khan, QJ, Kimler, BF, Sharma, P

“…Abstract Background: The impact of age at diagnosis on clinical presentation and treatment delivery for triple negative breast cancer (TNBC) is unclear…”
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Selective estrogen-receptor modulators for primary prevention of breast cancer: Breast cancer by FABIAN, Carol J, KIMLER, Bruce F

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Abstract P5-14-06: Lapatinib reverses endocrine resistance in select patients with HER2 negative, hormone positive metastatic breast cancer by Sharma, P, Kimler, BF, Ward, C, Wang, K, Ali, S, Balasubramanian, S, O'Dea, AP, Madhusudhana, S, Baccaray, S, Fabian, CJ, Schmitt, SB, Godwin, AK, Khan, QJ

“…Abstract Introduction: A significant proportion of breast cancer (BC) patients show primary or acquired resistance to endocrine therapy (ET). The cross-talk…”
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Abstract P5-16-02: Pathological complete response is associated with excellent outcomes in BRCA mutation associated triple negative breast cancer by Prochaska, LH, Godwin, AK, Kimler, BF, Lehn, C, Klemp, JR, O'Dea, A, Elia, M, Hoffmann, MS, Crane, G, McKittrick, R, Sheehan, M, Graff, SL, Madhusudhana, S, Khan, QJ, Jensen, RA, Sharma, P

“…Abstract Introduction: Pathological complete response (pCR) in unselected triple negative breast cancer (TNBC) is associated with excellent long-term survival…”
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Abstract P5-13-03: Fulvestrant plus anastrozole as neoadjuvant therapy in postmenopausal women with hormone receptor positive early breast cancer by Khan, QJ, Barr, JA, Britt, AS, Kimler, BF, Connor, CS, McGinness, M, Mammen, JMV, Wagner, JL, Amin, A, Springer, M, Baccaray, S, Fabian, CJ, Sing, AP, Sharma, P

“…Abstract Background: Aromatase inhibitors (AIs) are effective in reducing the risk of recurrence from breast cancer (BC) but 20% of patients (pts) with early…”
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Breast-tissue sampling for risk assessment and prevention by Fabian, C J, Kimler, B F, Mayo, M S, Khan, S A

“…Breast tissue and duct fluid provide a rich source of biomarkers to both aid in the assessment of short-term risk of developing breast cancer and predict and…”
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Short-Term Breast Cancer Prediction by Random Periareolar Fine-Needle Aspiration Cytology and the Gail Risk Model by Fabian, Carol J., Kimler, Bruce F., Zalles, Carola M., Klemp, Jennifer R., Kamel, Sahar, Zeiger, Sandy, Mayo, Matthew S.

“…Background: Biomarkers are needed to refine short-term breast cancer risk estimates from epidemiologic models and to measure response to prevention…”
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P3-09-03: Long-Chain Polyunsaturated Fatty Acid Intake and Its Relationship to Long-Chain Polyunsaturated Fatty Acids in Serum, Red Blood Cells and Breast Tissue by Harvey, KE, Li, S, Carlson, SE, Sullivan, DK, Klemp, JR, Kimler, BF, Fabian, CJ

“…Abstract Background Long chain omega-3 (n-3) poly unsaturated fatty acids (LCPUFA) have anti-inflammatory effects and are able to counteract the effects of the…”
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Abstract PD09-02: BRCA1 insufficiency is predictive of superior survival in patients with triple negative breast cancer treated with platinum based chemotherapy by Sharma, P, Stecklein, S, Kimler, BF, Klemp, JR, Khan, QJ, Fabian, CJ, Tawfik, OW, Connor, CS, McGinness, MK, Mammen, JMW, Jensen, RA

“…Abstract Introduction: Triple negative breast cancer (TNBC) and BRCA1-associated breast cancers share many histopathologic and molecular features. BRCA1 plays…”
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Abstract P4-10-01: High dose omega-3 fatty acid supplementation modulates breast tissue biomarkers in post-menopausal women at high risk for development of breast cancer by Fabian, CJ, Kimler, BF, Petroff, BK, Zalles, CM, Metheny, T, Nydegger, JL, Box, JA, Phillips, TL, Hidaka, BHH, Carlson, SE, deGraffenried, LA, Hursting, SD

“…Abstract Background: We conducted a pilot study of high dose omega-3 fatty acid (FA) supplementation in post-menopausal women to determine if risk biomarkers…”
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Abstract PD09-04: Weight Loss in Postmenopausal Women Is Associated with Modulation of Serum and Tissue Based Risk Biomarkers by Fabian, CJ, Kimler, BF, Phillips, TA, Zalles, CM, Klemp, JR, Malone, LM, Hursting, SD

“…Abstract Background In a pilot study, a structured program of reduced energy diet, physical activity, and weekly group behavioral intervention with other high…”
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Levels of 25-hydroxy-vitamin D in pre-menopausal women at high risk for development of breast cancer by Fabian, CJ, Kimler, BF, Phillips, T, Zalles, CM

“…Abstract Abstract #5079 Background: There is biologic and epidemiologic evidence to suggest an inverse relationship between vitamin D intake and the risk of…”
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l-Ascorbic acid induces apoptosis in acute myeloid leukemia cells via hydrogen peroxide-mediated mechanisms by Park, Seyeon, Han, Seong-Su, Park, Chan H, Hahm, Eun-Ryeong, Lee, Sook J, Park, Hye K, Lee, Se-Hoon, Kim, Won S, Jung, Chul Won, Park, Keunchil, Riordan, Hugh D, Kimler, Bruce F, Kim, Kihyun, Lee, Je-Ho

“…l-Ascorbic acid (LAA) is being investigated clinically for the treatment of patients with acute myeloid leukemia (AML) based on the observed effects of LAA on…”
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Comparison of immunohistochemistry by automated cellular imaging system (ACIS) versus fluorescence in-situ hybridization in the evaluation of HER-2/neu expression in primary breast carcinoma by Tawfik, O W, Kimler, B F, Davis, M, Donahue, J K, Persons, D L, Fan, F, Hagemeister, S, Thomas, P, Connor, C, Jewell, W, Fabian, C J

“…Aims : Immunohistochemistry (IHC) and fluorescence in‐situ hybridization (FISH) are both commonly used assays for evaluation of HER‐2/neu status in breast…”
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