Search Results - "Kimbrough, Denise"

Inhibition of class I histone deacetylase activity represses matrix metalloproteinase-2 and -9 expression and preserves LV function postmyocardial infarction by Mani, Santhosh K, Kern, Christine B, Kimbrough, Denise, Addy, Benjamin, Kasiganesan, Harinath, Rivers, William T, Patel, Risha K, Chou, James C, Spinale, Francis G, Mukherjee, Rupak, Menick, Donald R

“…Left ventricular (LV) remodeling, after myocardial infarction (MI), can result in LV dilation and LV pump dysfunction. Post-MI induction of matrix…”
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Differential hypertensive protease expression in the thoracic versus abdominal aorta by Ruddy, Jean Marie, MD, Akerman, Adam W., BS, MS, Kimbrough, Denise, PhD, Nadeau, Elizabeth K., BS, Stroud, Robert E., BS, MS, Mukherjee, Rupak, PhD, Ikonomidis, John S., MD, PhD, Jones, Jeffrey A., PhD

“…Abstract Background Hypertension (HTN), which is a major risk factor for cardiovascular morbidity and mortality, can drive pathologic remodeling of the macro-…”
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A Teenager with Hypertension: A Common Problem Leading to an Uncommon Diagnosis by Kimbrough, Denise M., Kyler, Kristen, Gilbert, Mileka, Selewski, David, Mennito, Sarah

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HDAC inhibition helps post-MI healing by modulating macrophage polarization by Kimbrough, Denise, Wang, Sabina H., Wright, Lillianne H., Mani, Santhosh K., Kasiganesan, Harinath, LaRue, Amanda C., Cheng, Qi, Nadig, Satish N., Atkinson, Carl, Menick, Donald R.

“…Following an acute myocardial infarction (MI) the extracellular matrix (ECM) undergoes remodeling in order to prevent dilation of the infarct area and maintain…”
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Abstract 223: Histone Deacetylase Inhibition Mediated Macrophage Polarization Suppresses Matrix Metalloproteinase-9 Upregulation Post Myocardial Infarction by Kimbrough, Denise M, Mani, Santhosh K, Kern, Chistine B, Kasiganesan, Harinath, Menick, Donald R

“…Abstract only Background: Following a myocardial infarction (MI) the extracellular matrix (ECM) undergoes massive remodeling to prevent rupture and maintain…”
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Differential Hypertensive Protease Expression in the Thoracic Versus Abdominal Aorta by Ruddy, Jean Marie, Akerman, Adam W, Kimbrough, Denise, Nadeau, Elizabeth N, Robert, Stroud E, Mukherje, Rupak, Ikonomidis, John S, Jones, Jeffrey A

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Transcriptional pathways and potential therapeutic targets in the regulation of Ncx1 expression in cardiac hypertrophy and failure by Menick, Donald R, Li, Mona S, Chernysh, Olga, Renaud, Ludivine, Kimbrough, Denise, Kasiganesan, Harinath, Mani, Santhosh K

“…Changes in cardiac gene expression contribute to the progression of heart failure by affecting cardiomyocyte growth, function, and survival. The Na(+)-Ca(2+)…”
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Abstract 204: Inhibition of Histone Deacetylase Activity Represses Matrix Metalloproteinase-9 Induction Through Regulation of Macrophage Polarization by Kimbrough, Denise M, Mani, Santhosh K, Kern, Christine B, Spinale, Francis G, Mukherjee, Rupak, Menick, Donald R

“…Abstract only Post myocardial infarction (MI) the extracellular matrix (ECM) undergoes massive remodeling in order to prevent dilation of the infarct area and…”
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Manipulating The Manipulators: A Role For Histone Deacetylase Inhibition In Macrophage Polarization by Kimbrough, Denise M

“…This work aims to develop an understanding of the molecular mechanisms behind remodeling involving inflammation; as well as how histone deacetylase (HDAC)…”
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Treating resistant hypertension with spironolactone by Berecek, Kathleen H, Kimbrough, Denise

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Clinical trials report by Berecek, Kathleen H., Kimbrough, Denise

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