Search Results - "Kimble, Brian"
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Bivalent hemagglutinin and neuraminidase influenza replicon particle vaccines protect pigs against influenza a virus without causing vaccine associated enhanced respiratory disease
Published in Vaccine (09-09-2022)“…•HA and NA replicon particle vaccines induced high levels of peripheral and local antibody.•HA and NA replicon particle vaccines protected from homologous…”
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Twist Modulates Breast Cancer Stem Cells by Transcriptional Regulation of CD24 Expression
Published in Neoplasia (New York, N.Y.) (01-12-2009)“…The cancer stem cell paradigm postulates that dysregulated tissue-specific stem cells or progenitor cells are precursors for cancer biogenesis. Consequently,…”
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3
Compatibility of H9N2 avian influenza surface genes and 2009 pandemic H1N1 internal genes for transmission in the ferret model
Published in Proceedings of the National Academy of Sciences - PNAS (19-07-2011)“…In 2009, a novel H1N1 influenza (pH1N1) virus caused the first influenza pandemic in 40 y. The virus was identified as a triple reassortant between avian,…”
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Aerosol Transmission from Infected Swine to Ferrets of an H3N2 Virus Collected from an Agricultural Fair and Associated with Human Variant Infections
Published in Journal of virology (30-07-2020)“…Influenza A viruses (IAV) sporadically transmit from swine to humans, typically associated with agricultural fairs in the United States. A human seasonal H3…”
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Alternative Reassortment Events Leading to Transmissible H9N1 Influenza Viruses in the Ferret Model
Published in Journal of Virology (01-01-2014)“…Article Usage Stats Services JVI Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley…”
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Antibody-Mediated Protective Mechanisms Induced by a Trivalent Parainfluenza Virus-Vectored Ebolavirus Vaccine
Published in Journal of virology (15-02-2019)“…Ebolaviruses Zaire (EBOV), Bundibugyo (BDBV), and Sudan (SUDV) cause human disease with high case fatality rates. Experimental monovalent vaccines, which all…”
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Characterization of influenza virus sialic acid receptors in minor poultry species
Published in Virology journal (09-12-2010)“…It is commonly accepted that avian influenza viruses (AIVs) bind to terminal α2,3 sialic acid (SA) residues whereas human influenza viruses bind to α2,6 SA…”
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Effects of Implementation of Lung Cancer Screening at One Veterans Affairs Medical Center
Published in Chest (01-11-2016)“…Background Lung cancer screening recommendations have been developed, but none are focused on veterans. We report the results of the lung cancer screening…”
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MicroRNA-based strategy to mitigate the risk of gain-of-function influenza studies
Published in Nature biotechnology (01-09-2013)“…A strategy exploiting species-specific miRNA expression may provide another layer of biosafety in gain-of-function influenza experiments. Recent…”
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Interspecies Transmission from Pigs to Ferrets of Antigenically Distinct Swine H1 Influenza A Viruses with Reduced Reactivity to Candidate Vaccine Virus Antisera as Measures of Relative Zoonotic Risk
Published in Viruses (29-10-2022)“…During the last decade, endemic swine H1 influenza A viruses (IAV) from six different genetic clades of the hemagglutinin gene caused zoonotic infections in…”
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Antigenic Characterization and Pandemic Risk Assessment of North American H1 Influenza A Viruses Circulating in Swine
Published in Microbiology spectrum (21-12-2022)“…The first pandemic of the 21st century was caused by an H1N1 influenza A virus (IAV) introduced from pigs into humans, highlighting the importance of swine as…”
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Swine-to-Ferret Transmission of Antigenically Drifted Contemporary Swine H3N2 Influenza A Virus Is an Indicator of Zoonotic Risk to Humans
Published in Viruses (24-01-2023)“…Human-to-swine transmission of influenza A (H3N2) virus occurs repeatedly and plays a critical role in swine influenza A virus (IAV) evolution and diversity…”
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Replication and transmission of mammalian-adapted H9 subtype influenza virus in pigs and quail
Published in Journal of general virology (01-09-2015)“…Influenza A virus is a major pathogen of birds, swine and humans. Strains can jump between species in a process often requiring mutations and reassortment,…”
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In Vivo Selection of H1N2 Influenza Virus Reassortants in the Ferret Model
Published in Journal of Virology (01-03-2013)“…Article Usage Stats Services JVI Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley…”
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Effects of Implementation of Lung Cancer Screening at a Veterans Affairs Medical Center
Published in Journal of the American College of Surgeons (01-10-2016)Get full text
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Swine Influenza A Viruses and the Tangled Relationship with Humans
Published in Cold Spring Harbor perspectives in medicine (01-03-2021)“…Influenza A viruses (IAVs) are the causative agents of one of the most important viral respiratory diseases in pigs and humans. Human and swine IAV are prone…”
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Vaccine-Associated Enhanced Respiratory Disease following Influenza Virus Infection in Ferrets Recapitulates the Model in Pigs
Published in Journal of virology (09-03-2022)“…Influenza A virus (IAV) causes respiratory disease in swine and humans. Vaccines are used to prevent influenza illness in both populations but must be…”
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A Single-Dose Intranasal Combination Panebolavirus Vaccine
Published in The Journal of infectious diseases (15-11-2023)“…Abstract Background Ebolaviruses Ebola (EBOV), Sudan (SUDV), and Bundibugyo (BDBV) cause severe human disease, which may be accompanied by hemorrhagic…”
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Twist Modulates Breast Cancer Stem Cells by Transcriptional Regulation of CD24 Expression1
Published in Neoplasia (New York, N.Y.) (01-12-2009)“…The cancer stem cell paradigm postulates that dysregulated tissue-specific stem cells or progenitor cells are precursors for cancer biogenesis. Consequently,…”
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Twist contributes to hormone resistance in breast cancer by down-regulating estrogen receptor alpha
Published in Oncogene (07-11-2011)“…The role of estrogen receptor alpha (ER) in breast cancer development and as a primary clinical marker for breast cancer prognosis is well documented. In this…”
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