Search Results - "Kimber, Wendy"

Dact1, a Nutritionally Regulated Preadipocyte Gene, Controls Adipogenesis by Coordinating the Wnt/β-Catenin Signaling Network by Lagathu, Claire, Christodoulides, Constantinos, Virtue, Sam, Cawthorn, William P, Franzin, Chiara, Kimber, Wendy A, Nora, Edoardo Dalla, Campbell, Mark, Medina-Gomez, Gema, Cheyette, Benjamin N R, Vidal-Puig, Antonio J, Sethi, Jaswinder K

“…Dact1 , a Nutritionally Regulated Preadipocyte Gene, Controls Adipogenesis by Coordinating the Wnt/β-Catenin Signaling Network Claire Lagathu 1 , Constantinos…”
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Tamoxifen-Induced Anorexia Is Associated With Fatty Acid Synthase Inhibition in the Ventromedial Nucleus of the Hypothalamus and Accumulation of Malonyl-CoA by LOPEZ, Miguel, LELLIOTT, Christopher J, O'RAHILLY, Stephen, SAHA, Asish K, DIEGUEZ, Carlos, VIDAL-PUIG, Antonio J, TOVAR, Sulay, KIMBER, Wendy, GALLEGO, Rosalia, VIRTUE, Sam, BLOUNT, Margaret, VAZQUEZ, Maria J, FINER, Nick, POWLES, Trevor J

“…Tamoxifen-Induced Anorexia Is Associated With Fatty Acid Synthase Inhibition in the Ventromedial Nucleus of the Hypothalamus and Accumulation of Malonyl-CoA…”
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Gene expression profiling of embryo-derived stem cells reveals candidate genes associated with pluripotency and lineage specificity by Tanaka, Tetsuya S, Kunath, Tilo, Kimber, Wendy L, Jaradat, Saied A, Stagg, Carole A, Usuda, Masayuki, Yokota, Takashi, Niwa, Hitoshi, Rossant, Janet, Ko, Minoru S H

“…Large-scale gene expression profiling was performed on embryo-derived stem cell lines to identify molecular signatures of pluripotency and lineage specificity…”
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Analysis of Genetic Variation in Akt2/PKB-β in Severe Insulin Resistance, Lipodystrophy, Type 2 Diabetes, and Related Metabolic Phenotypes by TAN, Karen, KIMBER, Wendy A, LUAN, Jianan, SOOS, Maria A, SEMPLE, Robert K, WAREHAM, Nicholas J, O'RAHILLY, Stephen, BARROSO, Ines

“…Analysis of Genetic Variation in Akt2/PKB-β in Severe Insulin Resistance, Lipodystrophy, Type 2 Diabetes, and Related Metabolic Phenotypes Karen Tan 1 2 ,…”
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Functional Characterization of Naturally Occurring Pathogenic Mutations in the Human Leptin Receptor by Kimber, Wendy, Peelman, Frank, Prieur, Xavier, Wangensteen, Teresia, O'Rahilly, Stephen, Tavernier, Jan, Farooqi, I. Sadaf

“…We have recently reported the first naturally occurring missense mutations in the leptin receptor (LR) in patients with severe obesity. We have examined the…”
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Interaction of the protein tyrosine phosphatase PTPL1 with the PtdIns(3,4)P2-binding adaptor protein TAPP1 by Kimber, Wendy A, Deak, Maria, Prescott, Alan R, Alessi, Dario R

“…It has been postulated that PtdIns(3,4) P (2), one of the immediate breakdown products of PtdIns(3,4,5) P (3), functions as a signalling molecule in insulin-…”
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Evidence that the tandem-pleckstrin-homology-domain-containing protein TAPP1 interacts with Ptd(3,4)P2 and the multi-PDZ-domain-containing protein MUPP1 in vivo by Kimber, Wendy A, Trinkle-Mulcahy, Laura, Cheung, Peter C F, Deak, Maria, Marsden, Louisa J, Kieloch, Agnieszka, Watt, Stephen, Javier, Ronald T, Gray, Alex, Downes, C Peter, Lucocq, John M, Alessi, Dario R

“…PtdIns(3,4,5)P3 is an established second messenger of growth-factor and insulin-induced signalling pathways. There is increasing evidence that one of the…”
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Detection of novel intracellular agonist responsive pools of phosphatidylinositol 3,4-bisphosphate using the TAPP1 pleckstrin homology domain in immunoelectron microscopy by Watt, Stephen A, Kimber, Wendy A, Fleming, Ian N, Leslie, Nick R, Downes, C Peter, Lucocq, John M

“…PtdIns(3,4) P (2), a breakdown product of the lipid second messenger PtdIns(3,4,5) P (3), is a key signalling molecule in pathways controlling various cellular…”
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Targeted Mutagenesis of the Hira Gene Results in Gastrulation Defects and Patterning Abnormalities of Mesoendodermal Derivatives Prior to Early Embryonic Lethality by Roberts, Catherine, Sutherland, Helen F., Farmer, Hannah, Kimber, Wendy, Halford, Stephanie, Carey, Alisoun, Brickman, Joshua M., Wynshaw-Boris, Anthony, Scambler, Peter J.

“…Article Usage Stats Services MCB Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley…”
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Transcriptome analysis of mouse stem cells and early embryos by Sharov, Alexei A, Piao, Yulan, Matoba, Ryo, Dudekula, Dawood B, Qian, Yong, VanBuren, Vincent, Falco, Geppino, Martin, Patrick R, Stagg, Carole A, Bassey, Uwem C, Wang, Yuxia, Carter, Mark G, Hamatani, Toshio, Aiba, Kazuhiro, Akutsu, Hidenori, Sharova, Lioudmila, Tanaka, Tetsuya S, Kimber, Wendy L, Yoshikawa, Toshiyuki, Jaradat, Saied A, Pantano, Serafino, Nagaraja, Ramaiah, Boheler, Kenneth R, Taub, Dennis, Hodes, Richard J, Longo, Dan L, Schlessinger, David, Keller, Jonathan, Klotz, Emily, Kelsoe, Garnett, Umezawa, Akihiro, Vescovi, Angelo L, Rossant, Janet, Kunath, Tilo, Hogan, Brigid L M, Curci, Anna, D'Urso, Michele, Kelso, Janet, Hide, Winston, Ko, Minoru S H

“…Understanding and harnessing cellular potency are fundamental in biology and are also critical to the future therapeutic use of stem cells. Transcriptome…”
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Deletion of 150 kb in the Minimal Digeorge/Velocardiofacial Syndrome Critical Region in Mouse by Kimber, Wendy L., Hsieh, Patrick, Hirotsune, Shinji, Yuva-Paylor, Lisa, Sutherland, Helen F., Chen, Amy, Ruiz-Lozano, Pilar, Hoogstraten-Miller, Shelley L., Chien, Kenneth R., Paylor, Richard, Scambler, Peter J., Wynshaw-Boris, Anthony

“…Deletions or rearrangements of human chromosome 22q11 lead to a variety of related clinical syndromes such as DiGeorge syndrome (DGS) and velocardiofacial…”
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Cystic fibrosis in the mouse by targeted insertional mutagenesis by Dorin, Julia R, Dickinson, Paul, Alton, Eric W. F. W, Smith, Stephen N, Geddes, Duncan M, Stevenson, Barbara J, Kimber, Wendy L, Fleming, Stewart, Clarke, Alan R, Hooper, Martin L, Anderson, Louise, Beddington, Rosa S. P, Porteous, David J

“…Cystic fibrosis is a fatal genetic disorder which afflicts 50,000 people worldwide. A viable animal model would be invaluable for investigating and combating…”
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Efficacy of 2-methoxyethoxy-modified antisense oligonucleotides for the study of mouse preimplantation development by Kimber, Wendy L, Puri, Nitin, Borgmeyer, Carol, Ritter, Donna, Sharov, Alexei, Seidman, Michael, Ko, Minoru SH

“…The advent of microarray technology, coupled with the availability of mouse cDNA collections derived specifically from preimplantation embryos, helps to…”
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Clinical and Molecular Genetic Spectrum of Congenital Deficiency of the Leptin Receptor by Farooqi, I. Sadaf, Wangensteen, Teresia, Collins, Stephan, Kimber, Wendy, Matarese, Giuseppe, Keogh, Julia M, Lank, Emma, Bottomley, Bill, Lopez-Fernandez, Judith, Ferraz-Amaro, Ivan, Dattani, Mehul T, Ercan, Oya, Myhre, Anne Grethe, Retterstol, Lars, Stanhope, Richard, Edge, Julie A, McKenzie, Sheila, Lessan, Nader, Ghodsi, Maryam, De Rosa, Veronica, Perna, Francesco, Fontana, Silvia, Barroso, Inês, Undlien, Dag E, O'Rahilly, Stephen

“…Of 300 persons selected for early-onset obesity, hyperphagia, and consanguineous parentage, 8 had mutations in the leptin-receptor gene ( LEPR ). Biochemical…”
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Liposomal transfection efficiency and toxicity on glioma cell lines: in vitro and in vitro studies by Bell, Helen, Kimber, Wendy L, Li, Mingwei, Whittle, Ian R

“…TO evaluate the influence of cell type and cationic liposomal formulation on gene transfection efficiency three liposomes (lipofectin, lipofectamine and DOTAP)…”
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Foxl2 disruption causes mouse ovarian failure by pervasive blockage of follicle development by Uda, Manuela, Ottolenghi, Chris, Crisponi, Laura, Garcia, Jose Elias, Deiana, Manila, Kimber, Wendy, Forabosco, Antonino, Cao, Antonio, Schlessinger, David, Pilia, Giuseppe

“…FOXL2 mutations cause gonadal dysgenesis or premature ovarian failure (POF) in women, as well as eyelid/forehead dysmorphology in both sexes (the…”
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Enhancing the efficiency of introducing precise mutations into the mouse genome by hit and run gene targeting by Dickinson, P, Kimber, W L, Kilanowski, F M, Webb, S, Stevenson, B J, Porteous, D J, Dorin, J R

“…The creation of precise clinical mutations by targeting is important in elucidating disease pathogenesis using mouse models. 'Hit and run' gene targeting is an…”
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Cloning and mapping of murine Dgcr2 and its homology to the Sez-12 seizure-related protein by Taylor, C, Wadey, R, O'Donnell, H, Roberts, C, Mattei, M G, Kimber, W L, Wynshaw-Boris, A, Scambler, P J

“…Hemizygosity for a region of human Chromosome (Chr) 22q11 has been associated with a wide range of congenital malformation syndromes. The major abnormalities…”
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Dact1, a Nutritionally Regulated Preadipocyte Gene, Controls Adipogenesis by Coordinating the Wnt/[beta]-Catenin Signaling Network by Lagathu, Claire, Christodoulides, Constantinos, Virtue, Sam, Cawthorn, William P, Franzin, Chiara, Kimber, Wendy A, Nora, Edoardo Dalla, Campbell, Mark, Medina-Gomez, Gema, Cheyette, Benjamin N R, Vidal-Puig, Antonio J, Sethi, Jaswinder K

“…Wnt signaling inhibits adipogenesis, but its regulation, physiological relevance, and molecular effectors are poorly understood. Here, we identify the Wnt…”
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Analysis of Genetic Variation in Akt2/PKB-[beta] in Severe Insulin Resistance, Lipodystrophy, Type 2 Diabetes, and Related Metabolic Phenotypes by Tan, Karen, Kimber, Wendy A, Luan, Jian'an, Soos, Maria A

“…We previously reported a family in which a heterozygous missense mutation in Akt2 led to a dominantly inherited syndrome of insulin-resistant diabetes and…”
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