Search Results - "Kimball, E S"

Modulation of gastrointestinal function by MuDelta, a mixed µ opioid receptor agonist/ µ opioid receptor antagonist by Wade, PR, Palmer, JM, McKenney, S, Kenigs, V, Chevalier, K, Moore, BA, Mabus, JR, Saunders, PR, Wallace, NH, Schneider, CR, Kimball, ES, Breslin, HJ, He, W, Hornby, PJ

“…BACKGROUND & PURPOSE Loperamide is a selective µ opioid receptor agonist acting locally in the gastrointestinal (GI) tract as an effective anti‐diarrhoeal but…”
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Vanilloid receptor 1 antagonists attenuate disease severity in dextran sulphate sodium‐induced colitis in mice by Kimball, E. S., Wallace, N. H., Schneider, C. R., D'Andrea, M. R., Hornby, P. J.

“…Neurogenic mechanisms have been implicated in the induction of inflammatory bowel disease (IBD). Vanilloid receptor type 1 (TRPV1) has been visualized on nerve…”
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Stimulation of neuronal receptors, neuropeptides and cytokines during experimental oil of mustard colitis by Kimball, E. S., Prouty, S. P., Pavlick, K. P., Wallace, N. H., Schneider, C. R., Hornby, P. J.

“…Oil of mustard (OM), administered intracolonically, produces severe colitis in mice that is maximized within 3 days. The purpose of this study was to…”
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Drug usage patterns and treatment costs in newly-diagnosed type 2 diabetes mellitus cases, 2007 vs 2012: findings from a large US healthcare claims database analysis by Weng, W, Liang, Y, Kimball, E S, Hobbs, T, Kong, S, Sakurada, B, Bouchard, J

“…Objective To explore trends in demographics, comorbidities, anti-diabetic drug usage, and healthcare utilization costs in patients with newly-diagnosed type 2…”
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Levamisole Effects on Major Histocompatibility Complex and Adhesion Molecule Expression and on Myeloid Cell Adhesion to Human Colon Tumor Cell Lines by Kimball, Edward S., Fisher, M. Carolyn

“…Background: The drug levamisole has been successfully used in combination with fluorouracil to increase the disease-free interval and survival of patients who…”
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Substance P, cytokines, and arthritis by Kimball, E S

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Activation of cytokine production and adhesion molecule expression on THP-1 myelomonocytic cells by macrophage colony-stimulating factor in combination with interferon-gamma by Kimball, E S, Kovacs, E, Clark, M C, Schneider, C R

“…THP-1 myelomonocytic leukemia cells cultured with either macrophage colony-stimulating factor (M-CSF) or interferon-gamma (IFN-gamma) alone produce, at best,…”
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Potentiation of IL-1-induced BALB/3T3 fibroblast proliferation by neuropeptides by Kimball, ES, Fisher, MC

“…The interactions between IL-1 and several neuropeptides associated with pain and inflammation were examined in the context of fibroblast proliferation as a…”
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Interleukin 1 activity in normal human urine by Kimball, ES, Pickeral, SF, Oppenheim, JJ, Rossio, JL

“…Urine concentrates from normal individuals were shown to contain interleukin 1 (IL 1)-like activity when tested directly on human dermal fibroblasts and on…”
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Levamisole causes differential cytokine expression by elicited mouse peritoneal macrophages by Kimball, E S, Schneider, C R, Fisher, M C, Clark, M C

“…Thioglycolate-elicited peritoneal macrophages from normal C57B1/6J mice were examined in vitro for bacterial lipopolysaccharide (LPS)-stimulated interleukin-1…”
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Purification and characterization of a low molecular weight transforming growth factor from the urine of melanoma patients by Kim, M K, Warren, T C, Kimball, E S

“…A low Mr human transforming growth factor (TGF) present in melanoma patients' urine has been purified approximately 200,000-fold to apparent homogeneity…”
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The combined immunological and antinociceptive defects of beige-J mice: the possible existence of a 'mu-repressin' by Raffa, R B, Mathiasen, J R, Kimball, E S, Vaught, J L

“…A selective non-responsiveness to the analgesic effects of opioid mu receptor-, but not opioid delta receptor-, mediated antinociception in the tail-flick test…”
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Rationale, Design, and Synthesis of Novel Phenyl Imidazoles as Opioid Receptor Agonists for Gastrointestinal Disorders by Breslin, Henry J, Miskowski, Tamara A, Rafferty, Bryan M, Coutinho, Santosh V, Palmer, Jeffrey M, Wallace, Nathaniel H, Schneider, Craig R, Kimball, Edward S, Zhang, Sui-Po, Li, Jian, Colburn, Raymond W, Stone, Dennis J, Martinez, Rebecca P, He, Wei

“…A small series of novel, imidazoles 4 have been prepared that exhibit very good binding affinities for the δ and μ opioid receptors (ORs), as well as…”
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Angiogenesis in pannus formation by Kimball, E S, Gross, J L

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Distinct high-performance liquid chromatography pattern of transforming growth factor activity in urine of cancer patients as compared with that of normal individuals by KIMBALL, E. S, BOHN, W. H, COCKLEY, K. D, WARREN, T. C, SHERWIN, S. A

“…Reverse-phase high-performance liquid chromatography (HPLC) performed on urine from cancer patients and normal controls revealed the presence of seven…”
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Structure of class I major histocompatibility antigens by Kimball, E S, Coligan, J E

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Absence of significant effects by levamisole on circulating neutrophil levels in normal mice treated with 5-FU by Kimball, E S, Fisher, M C

“…When B6C3F1 mice were given a single intravenous (i.v.) injection of 150 mg/kg 5-fluorouracil (5-FU) their levels of circulating neutrophils plummeted,…”
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Epidermal growth factor (EGF) binding to membranes immobilized in microtiter wells and estimation of EGF-related transforming growth factor activity by Kimball, E S, Warren, T C

“…The binding of radiolabeled epidermal growth factor (EGF) to immobilized A-431 target cell membranes coupled to polyvinyl chloride microtiter wells is…”
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Substance P, neurokinin A, and neurokinin B induce generation of IL-1- like activity in P388D1 cells. Possible relevance to arthritic disease by Kimball, ES, Persico, FJ, Vaught, JL

“…Near nanomolar concentrations of substance P induce production of IL-1 or an IL-1-like activity in the mouse macrophage cell line P388D1. Moreover, this could…”
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Comparison of growth factors functionally related to epidermal growth factor in the urine of normal and human tumor-bearing athymic mice by TWARDZIK, D. R, KIMBALL, E. S, SHERWIN, S. A, RANCHALIS, J. E, TODARO, G. J

“…Urine from nude mice contains epidermal growth factor (EGF) and a minor acid-stable component with an apparent molecular weight of 20,000, which competes with…”
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