Search Results - "Kimani, Stanley G."

Requirement of Gamma-Carboxyglutamic Acid Modification and Phosphatidylserine Binding for the Activation of Tyro3, Axl, and Mertk Receptors by Growth Arrest-Specific 6 by Geng, Ke, Kumar, Sushil, Kimani, Stanley G, Kholodovych, Vladyslav, Kasikara, Canan, Mizuno, Kensaku, Sandiford, Oleta, Rameshwar, Pranela, Kotenko, Sergei V, Birge, Raymond B

“…The Tyro3, Axl, and Mertk (TAM) receptors are homologous type I receptor tyrosine kinases that have critical functions in the clearance of apoptotic cells in…”
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Overexpression of MERTK Receptor Tyrosine Kinase in Epithelial Cancer Cells Drives Efferocytosis in a Gain-of-Function Capacity by Nguyen, Khanh-Quynh N., Tsou, Wen-I, Calarese, Daniel A., Kimani, Stanley G., Singh, Sukhwinder, Hsieh, Shelly, Liu, Yongzhang, Lu, Bin, Wu, Yi, Garforth, Scott J., Almo, Steve C., Kotenko, Sergei V., Birge, Raymond B.

“…MERTK, a member of the TAM (TYRO3, AXL, and MERTK) receptor tyrosine kinases, has complex and diverse roles in cell biology. On the one hand, knock-out of…”
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Antioxidant Inhibitors Potentiate the Cytotoxicity of Photodynamic Therapy by Kimani, Stanley G., Phillips, James B., Bruce, James I., MacRobert, Alexander J., Golding, Jon P.

“…Photodynamic therapy (PDT) is an increasingly popular anticancer treatment that uses photosensitizer, light and tissue oxygen to generate cytotoxic reactive…”
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Fully Protected Glycosylated Zinc (II) Phthalocyanine Shows High Uptake and Photodynamic Cytotoxicity in MCF-7 Cancer Cells by Kimani, Stanley G., Shmigol, Tatiana A., Hammond, Samantha, Phillips, James B., Bruce, James I., MacRobert, Alexander J., Malakhov, Mikhail V., Golding, Jon P.

“…Phthalocyanine photosensitizers are effective in anticancer photodynamic therapy (PDT) but suffer from limited solubility, limited cellular uptake and limited…”
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Ligand Activation of TAM Family Receptors-Implications for Tumor Biology and Therapeutic Response by Davra, Viralkumar, Kimani, Stanley G, Calianese, David, Birge, Raymond B

“…The TAM family of receptors (i.e., Tyro3, Axl, and Mertk), and their ligands Growth arrest specific factor 6 (Gas6) and Protein S (Pros1) contribute to several…”
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Small molecule inhibitors block Gas6-inducible TAM activation and tumorigenicity by Kimani, Stanley G., Kumar, Sushil, Bansal, Nitu, Singh, Kamalendra, Kholodovych, Vladyslav, Comollo, Thomas, Peng, Youyi, Kotenko, Sergei V., Sarafianos, Stefan G., Bertino, Joseph R., Welsh, William J., Birge, Raymond B.

“…TAM receptors (Tyro-3, Axl, and Mertk) are a family of three homologous type I receptor tyrosine kinases that are implicated in several human malignancies…”
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Normalization of TAM post-receptor signaling reveals a cell invasive signature for Axl tyrosine kinase by Kimani, Stanley G, Kumar, Sushil, Davra, Viralkumar, Chang, Yun-Juan, Kasikara, Canan, Geng, Ke, Tsou, Wen-I, Wang, Shenyan, Hoque, Mainul, Boháč, Andrej, Lewis-Antes, Anita, De Lorenzo, Mariana S, Kotenko, Sergei V, Birge, Raymond B

“…Tyro3, Axl, and Mertk (TAMs) are a family of three conserved receptor tyrosine kinases that have pleiotropic roles in innate immunity and homeostasis and when…”
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Opposite effects of PDGF-BB and prostaglandin E1 on cell-motility related processes are paralleled by modifications of distinct actin-binding proteins by van Wieringen, Tijs, Kimani, Stanley G, Hultgård-Ekwall, Anna-Karin, Forsberg, Jens, Reyhani, Vahid, Engström, Ake, Rubin, Kristofer

“…Prostaglandin E(1) (PGE(1)) lowers dermal interstitial fluid pressure (IFP) in vivo and inhibits fibroblast-mediated collagen gel contraction in vitro…”
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Opposite effects of PDGF-BB and prostaglandin E 1 on cell-motility related processes are paralleled by modifications of distinct actin-binding proteins by van Wieringen, Tijs, Kimani, Stanley G., Hultgård-Ekwall, Anna-Karin, Forsberg, Jens, Reyhani, Vahid, Engström, Åke, Rubin, Kristofer

“…Prostaglandin E 1 (PGE 1) lowers dermal interstitial fluid pressure (IFP) in vivo and inhibits fibroblast-mediated collagen gel contraction in vitro. PDGF-BB,…”
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Opposite effects of PDGF-BB and prostaglandin E(1) on cell-motility related processes are paralleled by modifications of distinct actin-binding proteins by van Wieringen, Tijs, Kimani, Stanley G., Hultgard-Ekwall, Anna-Karin, Forsberg, Jens, Reyhani, Vahid, Engström, Åke, Rubin, Kristofer

“…Prostaglandin E(1) (PGE(1)) lowers dermal interstitial fluid pressure (IFP) in vivo and inhibits fibroblast-mediated collagen gel contraction in vitro…”
Get full text