Search Results - "Kimak, M A"

Hereditary Lymphedema: Evidence for Linkage and Genetic Heterogeneity by Ferrell, Robert E., Levinson, Kara L., Esman, Judith H., Kimak, Mark A., Lawrence, Elizabeth C., Michael Barmada, M., Finegold, David N.

“…Hereditary or primary lymphedema is a developmental disorder of the lymphatic system which leads to a disabling and disfiguring swelling of the extremities…”
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Missense mutations interfere with VEGFR-3 signalling in primary lymphoedema by Ferrell, Robert E, Karkkainen, Marika J, Lawrence, Elizabeth C, Kimak, Mark A, Levinson, Kara L, McTigue, Michele A, Alitalo, Kari, Finegold, David N

“…Primary lymphoedema is a rare, autosomal dominant disorder that leads to a disabling and disfiguring swelling of the extremities and, when untreated, tends to…”
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Truncating mutations in FOXC2 cause multiple lymphedema syndromes by FINEGOLD, David N, KIMAK, Mark A, LAWRENCE, Elizabeth C, LEVINSON, Kara L, CHERNISKE, Elizabeth M, POBER, Barbara R, DUNLAP, Jean W, FERRELL, Robert E

“…Hereditary lymphedemas are developmental disorders of the lymphatics resulting in edema of the extremities due to altered lymphatic flow. One such disorder,…”
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VEGFR3 gene structure, regulatory region, and sequence polymorphisms by Iljin, K, Karkkainen, M J, Lawrence, E C, Kimak, M A, Uutela, M, Taipale, J, Pajusola, K, Alhonen, L, Halmekytö, M, Finegold, D N, Ferrell, R E, Alitalo, K

“…Vascular endothelial growth factor receptor 3 (VEGFR-3) is required for cardiovascular development during embryogenesis. In adults, this receptor is expressed…”
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Energy requirements for diphtheria toxin translocation are coupled to the maintenance of a plasma membrane potential and a proton gradient by Hudson, T H, Scharff, J, Kimak, M A, Neville, D M

“…Translocation of diphtheria toxin (DT) or ricin to the cytosol is the rate-limiting step responsible for (pseudo) first-order decline in protein synthesis…”
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PI-10 by Feng, Y., Pollock, B. G., Ferrell, R. E., Kimak, M. A., Reynolds, C., Bies, R. R.

“…AIM To develop a population pharmacokinetic (PK) model using sparse data sampling from a geriatric depressed population with five‐year paroxetine treatment and…”
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Paroxetine: population pharmacokinetic analysis in late‐life depression using sparse concentration sampling by Feng, Yan, Pollock, Bruce G., Ferrell, Robert E., Kimak, Mark A., Iii, Charles F. Reynolds, Bies, Robert R.

“…Aim To develop a population pharmacokinetic (PK) model using sparse sampling of long‐term treatment with paroxetine in elderly depressed subjects,…”
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Lymphedema-distichiasis syndrome and FOXC2 gene mutation by Traboulsi, Elias I, Al-Khayer, Khouloud, Matsumoto, Masayuki, Kimak, Mark A, Crowe, Susan, Wilson, Steven E, Finegold, David N, Ferrell, Robert E, Meisler, David M

“…PURPOSE: To describe the clinical characteristics of a family with autosomal dominant lymphedema-distichiasis syndrome and to report the results of analysis of…”
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