Search Results - "Kim, Yong Kee"

Cancer Stem Cells as a Potential Target to Overcome Multidrug Resistance by Cho, Yena, Kim, Yong Kee

“…Multidrug resistance (MDR), which is a significant impediment to the success of cancer chemotherapy, is attributable to various defensive mechanisms in cancer…”
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The Inhibitory Effects of Eckol and Dieckol from Ecklonia stolonifera on the Expression of Matrix Metalloproteinase-1 in Human Dermal Fibroblasts by Joe, Min-Jeong, Kim, Su-Nam, Choi, Hye-Young, Shin, Woon-Seob, Park, Gab-Man, Kang, Dong-Won, Kim, Yong Kee

“…In order to develop new anti-photoaging agents, we examined the inhibitory effects of 29 seaweed extracts on transcriptional activities of NF-κB and AP-1, and…”
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Paedoksan ameliorates allergic disease through inhibition of the phosphorylation of STAT6 in DNCB-induced atopic dermatitis like mice by Lee, Sang Heon, Oh, Youngse, Bong, Sim-Kyu, Lee, Jin Woo, Park, No-June, Kim, Young-Joo, Park, Hyun Bong, Kim, Yong Kee, Kim, Seung Hyun, Kim, Su-Nam

“…Various allergic diseases such as atopic dermatitis (AD), allergic rhinitis, and asthma are considered incurable conditions that have yet to be fully…”
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Anti-obesity and hypolipidemic effects of Rheum undulatum in high-fat diet-fed C57BL/6 mice through protein tyrosine phosphatase 1B inhibition by Lee, Woojung, Yoon, Goo, Hwang, Ye Ran, Kim, Yong Kee, Kim, Su-Nam

“…Protein tyrosine phosphatase 1B (PTP1B) is important in the regulation of metabolic diseases and has emerged as a promising signaling target. Previously, we…”
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Protein arginine methyltransferases: promising targets for cancer therapy by Hwang, Jee Won, Cho, Yena, Bae, Gyu-Un, Kim, Su-Nam, Kim, Yong Kee

“…Protein methylation, a post-translational modification (PTM), is observed in a wide variety of cell types from prokaryotes to eukaryotes. With recent and rapid…”
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CARM1 phosphorylation at S595 by p38γ MAPK drives ROS-mediated cellular senescence by Cho, Yena, Kim, Yong Kee

“…CARM1 is predominantly localized in the nucleus and plays a pivotal role in maintaining mitochondrial homeostasis by regulating gene expression. It suppresses…”
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ROS-mediated cytoplasmic localization of CARM1 induces mitochondrial fission through DRP1 methylation by Cho, Yena, Kim, Yong Kee

“…The dynamic regulation of mitochondria through fission and fusion is essential for maintaining cellular homeostasis. In this study, we discovered a role of…”
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Histone Deacetylase Inhibitor Induction of P-Glycoprotein Transcription Requires Both Histone Deacetylase 1 Dissociation and Recruitment of CAAT/Enhancer Binding Protein β and pCAF to the Promoter Region by Kim, Su-Nam, Kim, Nam Hyun, Lee, Woojung, Seo, Dong-Wan, Kim, Yong Kee

“…Although histone deacetylase (HDAC) inhibitors are appreciated as a promising class of anticancer drugs, recent reports show that P-glycoprotein (P-gp) is…”
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Reversine Increases the Plasticity of Lineage-committed Cells toward Neuroectodermal Lineage by Lee, Eun Kyung, Bae, Gyu-Un, You, Jueng Soo, Lee, Jae Cheol, Jeon, Yae Jee, Park, Jong Woo, Park, Jae Hyun, Ahn, Seong Hoon, Kim, Yong Kee, Choi, Wahn Soo, Kang, Jong-Sun, Han, Gyoonhee, Han, Jeung-Whan

“…Functional dedifferentiation of lineage-committed cells toward pluripotency may have a great potential in regenerative medicine. Reversine has been shown to…”
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Compound K improves skin barrier function by increasing SPINK5 expression by Park, No-June, Bong, Sim-Kyu, Lee, Sullim, Jung, Yujung, Jegal, Hyun, Kim, Jinchul, Kim, Si-Kwan, Kim, Yong Kee, Kim, Su-Nam

“…Background: The skin acts as a barrier to protect organisms against harmful exogenous agents. Compound K (CK) is an active metabolite of ginsenoside Rb1, Rb2…”
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Ginsenoside Rb1 and Rb2 upregulate Akt/mTOR signaling-mediated muscular hypertrophy and myoblast differentiation by Go, Ga-Yeon, Jo, Ayoung, Seo, Dong-Wan, Kim, Woo-Young, Kim, Yong Kee, So, Eui-Young, Chen, Qian, Kang, Jong-Sun, Bae, Gyu-Un, Lee, Sang-Jin

“…Background: As a process of aging, skeletal muscle mass and function gradually decrease. It is reported that ginsenoside Rb1 and Rb2 play a role as…”
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PRMT6-mediated H3R2me2a guides Aurora B to chromosome arms for proper chromosome segregation by Kim, Seul, Kim, Nam Hyun, Park, Ji Eun, Hwang, Jee Won, Myung, Nayeon, Hwang, Ki-Tae, Kim, Young A, Jang, Chang-Young, Kim, Yong Kee

“…The kinase Aurora B forms the chromosomal passenger complex (CPC) together with Borealin, INCENP, and Survivin to mediate chromosome condensation, the…”
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Lysophosphatidic acid receptor 2 and Gi/Src pathway mediate cell motility through cyclooxygenase 2 expression in CAOV-3 ovarian cancer cells by Jeong, Kang Jin, Park, Soon Young, Seo, Ji Hye, Lee, Kyung Bok, Choi, Wahn Soo, Han, Jeung Whan, Kang, Jae Ku, Park, Chang Gyo, Kim, Yong Kee, Lee, Hoi Young

“…Lysophosphatidic acid (LPA) is a bioactive phospholipids and involves in various cellular events, including tumor cell migration. In the present study, we…”
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Oncogenic Impact of TONSL, a Homologous Recombination Repair Protein at the Replication Fork, in Cancer Stem Cells by Lee, Hani, Ha, Sojung, Choi, SeokGyeong, Do, Soomin, Yoon, Sukjoon, Kim, Yong Kee, Kim, Woo-Young

“…We investigated the role of TONSL, a mediator of homologous recombination repair (HRR), in stalled replication fork double-strand breaks (DSBs) in cancer…”
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Diosmetin and Its Glycoside, Diosmin, Improve Atopic Dermatitis- Like Lesions in 2,4-Dinitrochlorobenzene-Induced Murine Models by Park, Sang-a, Bong, Sim-Kyu, Lee, Jin Woo, Park, No-June, Choi, Yongsoo, Kim, Sang Moo, Yang, Min Hye, Kim, Yong Kee, Kim, Su-Nam

“…Naturally derived diosmetin and its glycoside diosmin are known to be effective in treating inflammatory disease. This study was performed to determine whether…”
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TGF-${\beta}$1 Induction of p21$^{WAF1/Cip1}$ Requires Smad-Independent Protein Kinase C Signaling Pathway by Kim, Yong-Kee

“…Although it has been demonstrated that p21$^{WAF1/Cip1}$ could be induced by transforming growth factor-${\beta}$1 (TGF-${\beta}$1) in a Smad-dependent manner,…”
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Norepinephrine induces VEGF expression and angiogenesis by a hypoxia-inducible factor-1α protein-dependent mechanism by SOON YOUNG PARK, JOO HEE KANG, KANG JIN JEONG, LEE, Jangsoon, JEONG WHAN HAN, WAHN SOO CHOI, YONG KEE KIM, KANG, Jaeku, CHANG GYO PARK, HOI YOUNG LEE

“…A growing number of studies have demonstrated that physiological factors can influence the progression of several cancers via cellular immune function,…”
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Pectolinarigenin, an aglycone of pectolinarin, has more potent inhibitory activities on melanogenesis than pectolinarin by Lee, Sullim, Lee, Da-Hye, Kim, Jin-Chul, Um, Byung Hun, Sung, Sang Hyun, Jeong, Lak Shin, Kim, Yong Kee, Kim, Su-Nam

“…Pectolinarin and pectolinarigenin have been reported to be major compounds in Cirsium setidens. In the present study, we demonstrated inhibitory effects of…”
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PRMT7 Inhibitor SGC8158 Enhances Doxorubicin-Induced DNA Damage and Its Cytotoxicity by Jeong, Ahyeon, Cho, Yena, Cho, Minkyeong, Bae, Gyu-Un, Song, Dae-Geun, Kim, Su-Nam, Kim, Yong Kee

“…Protein arginine methyltransferase 7 (PRMT7) regulates various cellular responses, including gene expression, cell migration, stress responses, and stemness…”
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Histone deacetylase inhibitor activity in royal jelly might facilitate caste switching in bees by Spannhoff, Astrid, Kim, Yong Kee, Raynal, Noel J -M, Gharibyan, Vazganush, Su, Ming-Bo, Zhou, Yue-Yang, Li, Jia, Castellano, Sabrina, Sbardella, Gianluca, Issa, Jean-Pierre J, Bedford, Mark T

“…Worker and queen bees are genetically indistinguishable. However, queen bees are fertile, larger and have a longer lifespan than their female worker…”
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