Search Results - "Kim, Yon Hui"
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A nanowire-based label-free immunosensor: Direct incorporation of a PSA antibody in electropolymerized polypyrrole
Published in Biosensors & bioelectronics (15-07-2014)“…We have suggested a novel method for the preparation of a label-free electrochemical immunosensor for the detection of prostate-specific antigen (PSA) as…”
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2
Identifying molecular drivers of gastric cancer through next-generation sequencing
Published in Cancer letters (01-11-2013)“…Highlights ► Next-generation sequencing technology provides a powerful way to identify molecular drivers of gastric cancer. ► Targeted exome sequencing studies…”
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High Expression of PRNP Predicts Poor Prognosis in Korean Patients with Gastric Cancer
Published in Cancers (28-06-2022)“…Gastric cancer (GC) has the highest occurrence and fourth-highest mortality rate of all cancers in Korea. Although survival rates are improving with the…”
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Differential effects, on oncogenic pathway signalling, by derivatives of the HNF4 α inhibitor BI6015
Published in British journal of cancer (05-03-2019)“…Background Gastric cancer (GC) is a highly heterogeneous disease with few “targeted” therapeutic options. Previously, we demonstrated involvement of the…”
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Second-Generation JK-206 Targets the Oncogenic Signal Mediator RHOA in Gastric Cancer
Published in Cancers (22-03-2022)“…Ras homologous A (RHOA), a signal mediator and a GTPase, is known to be associated with the progression of gastric cancer (GC), which is the fourth most common…”
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Antitumor agent PX-12 inhibits HIF-1α protein levels through an Nrf2/PMF-1-mediated increase in spermidine/spermine acetyl transferase
Published in Cancer chemotherapy and pharmacology (01-08-2011)“…Purpose Thioredoxin-1 (Trx-1) redox signaling regulates multiple aspects of cell growth and survival, and elevated tumor levels of Trx-1 have been associated…”
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AMPKα Modulation in Cancer Progression: Multilayer Integrative Analysis of the Whole Transcriptome in Asian Gastric Cancer
Published in Cancer research (Chicago, Ill.) (15-05-2012)“…Gastric cancer is the most common cancer in Asia and most developing countries. Despite the use of multimodality therapeutics, it remains the second leading…”
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Rational design of small molecule RHOA inhibitors for gastric cancer
Published in The pharmacogenomics journal (01-08-2020)“…Previously, we identified Ras homologous A (RHOA) as a major signaling hub in gastric cancer (GC), the third most common cause of cancer death in the world,…”
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Friends and family: A literature review on how high school social groups influence advanced math and science coursetaking
Published in Education policy analysis archives (12-06-2017)“…In this study, we synthesized the literature on how informal contexts, namely friends and family social groups, shape high school students’ likelihood of…”
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The homeobox gene Hex regulates hepatocyte differentiation from embryonic stem cell–derived endoderm
Published in Hepatology (Baltimore, Md.) (01-02-2010)“…We investigated the role of the hematopoietically expressed homeobox (Hex) in the differentiation and development of hepatocytes within embryonic stem cell…”
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Improving gastric cancer preclinical studies using diverse in vitro and in vivo model systems
Published in BMC cancer (09-03-2016)“…"Biomarker-driven targeted therapy," the practice of tailoring patients' treatment to the expression/activity levels of disease-specific genes/proteins,…”
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Mg2+ effect on argonaute and RNA duplex by molecular dynamics and bioinformatics implications
Published in PloS one (17-10-2014)“…RNA interference (RNAi), mediated by small non-coding RNAs (e.g., miRNAs, siRNAs), influences diverse cellular functions. Highly complementary miRNA-target RNA…”
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13
Network Comparison of Inflammation in Colorectal Cancer and Alzheimer’s Disease
Published in BioMed research international (01-01-2015)“…Recently, a large clinical study revealed an inverse correlation of individual risk of cancer versus Alzheimer’s disease (AD). However, no explanation exists…”
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PATHOME-Drug: a subpathway-based polypharmacology drug-repositioning method
Published in Bioinformatics (03-01-2022)“…Abstract Motivation Drug repositioning reveals novel indications for existing drugs and in particular, diseases with no available drugs. Diverse computational…”
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Effects of operational decisions on the diffusion of epidemic disease: A system dynamics modeling of the MERS-CoV outbreak in South Korea
Published in Journal of theoretical biology (21-05-2017)“…•Development of a macro-level health system dynamics model.•Performance measurements of epidemic disease diffusion and patient-care performance from an…”
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An Electroactive Biotin-Doped Polypyrrole Substrate That Immobilizes and Releases EpCAM-Positive Cancer Cells
Published in Angewandte Chemie International Edition (25-04-2014)“…The specific capture and remotely controlled release of the EpCAM‐positive cancer cells from biotin‐doped polypyrrole (Ppy) films in response to an electrical…”
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Peer tutoring instructional practice and kindergartners' achievement and socioemotional development
Published in Educational studies (03-09-2019)“…This study examines how the use of peer tutoring instructional practices links to students' outcomes during kindergarten. Examining this pedagogical strategy…”
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Establishment of an apoptosis-resistant and growth-controllable cell line by transfecting with inducible antisense c-Jun gene
Published in Biotechnology and bioengineering (05-04-1998)“…F‐MEL cells were transfected with the c‐jun antisense gene located downstream of a glucocorticoid‐inducible MMTV promoter, and the obtained cells were named…”
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Detection of PIWI and piRNAs in the mitochondria of mammalian cancer cells
Published in Biochemical and biophysical research communications (28-03-2014)“…•piRNA sequences were mapped to human mitochondrial (mt) genome.•We inspected small RNA-Seq datasets from somatic cell mt subcellular fractions.•Piwi and piRNA…”
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HNF4α is a therapeutic target that links AMPK to WNT signalling in early-stage gastric cancer
Published in Gut (01-01-2016)“…Worldwide, gastric cancer (GC) is the fourth most common malignancy and the most common cancer in East Asia. Development of targeted therapies for this disease…”
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