Search Results - "Kim, Yikwon"
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Comparative proteomic profiling of pancreatic ductal adenocarcinoma cell lines
Published in Molecules and cells (01-12-2014)“…Pancreatic cancer is one of the most fatal cancers and is associated with limited diagnostic and therapeutic modalities. Currently, gemcitabine is the only…”
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Interactome analysis of AMP-activated protein kinase (AMPK)-α1 and -β1 in INS-1 pancreatic beta-cells by affinity purification-mass spectrometry
Published in Scientific reports (14-03-2014)“…The heterotrimeric enzyme AMP-activated protein kinase (AMPK) is a major metabolic factor that regulates the homeostasis of cellular energy. In particular,…”
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3
Label-Free Quantitative Proteomics and N-terminal Analysis of Human Metastatic Lung Cancer Cells
Published in Molecules and cells (2014)“…Proteomic analysis is helpful in identifying cancerassociated proteins that are differentially expressed and fragmented that can be annotated as dysregulated…”
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Comparative Proteomic Profiling of Pancreatic Ductal Adenocarcinoma Cell Lines
Published in Molecules and cells (2014)“…Pancreatic cancer is one of the most fatal cancers and is associated with limited diagnostic and therapeutic modalities. Currently, gemcitabine is the only…”
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Characterization for the Similarity Assessment between SB12 (Eculizumab Biosimilar) and Eculizumab Using State-of-the-Art Analytical Method
Published in Blood (15-11-2022)Get full text
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Characterization for the Similarity Assessment between Proposed Biosimilar SB12 and Eculizumab Reference Product Using a State-of-the-Art Analytical Method
Published in BioDrugs : clinical immunotherapeutics, biopharmaceuticals, and gene therapy (01-07-2023)“…Background SB12 is being developed as a proposed biosimilar to eculizumab reference product (RP), a humanized monoclonal antibody (IgG2/4 kappa immunoglobulin)…”
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Characterization of the membrane proteome and N-glycoproteome in BV-2 mouse microglia by liquid chromatography-tandem mass spectrometry
Published in BMC genomics (04-02-2014)“…Microglial cells are resident macrophages of the central nervous system and important cellular mediators of the immune response and neuroinflammatory…”
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In-depth proteomic analysis of mouse microglia using a combination of FASP and StageTip-based, high pH, reversed-phase fractionation
Published in Proteomics (Weinheim) (01-10-2013)“…Microglia are major immune cells in the central nervous system. A characterization of microglia proteome would facilitate on the study of microglial functions…”
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Biomarker Development for Intraductal Papillary Mucinous Neoplasms Using Multiple Reaction Monitoring Mass Spectrometry
Published in Journal of proteome research (04-01-2016)“…Intraductal papillary mucinous neoplasm (IPMN) is a common precursor of pancreatic cancer (PC). Much clinical attention has been directed toward IPMNs due to…”
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Comprehensive Phosphoproteome Analysis of INS-1 Pancreatic Beta-Cells using Various Digestion Strategies Coupled with Liquid Chromatography–Tandem Mass Spectrometry
Published in Journal of proteome research (06-04-2012)“…Type 2 diabetes results from aberrant regulation of the phosphorylation cascade in beta-cells. Phosphorylation in pancreatic beta-cells has not been examined…”
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Developing cancer prediction model based on stepwise selection by AUC measure for proteomics data
Published in 2015 IEEE International Conference on Bioinformatics and Biomedicine (BIBM) (01-11-2015)“…Since most of the cancer markers that have been reported are obtained directly from cancer tissues, it is difficult to use them for early diagnosis of cancer…”
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Conference Proceeding -
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Label-free quantitative proteomics and N-terminal analysis of human metastatic lung cancer cells
Published in Molecules and cells (01-06-2014)“…Proteomic analysis is helpful in identifying cancer-associated proteins that are differentially expressed and fragmented that can be annotated as dysregulated…”
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Differential Proteome Profiling Using iTRAQ in Microalbuminuric and Normoalbuminuric Type 2 Diabetic Patients
Published in Experimental diabetes research (01-01-2012)“…Diabetic nephropathy (DN) is a long-term complication of diabetes mellitus that leads to end-stage renal disease. Microalbuminuria is used for the early…”
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Differential Proteome Profiling Using iTRAQ in Microalbuminuric and Normoalbuminuric Type 2 Diabetic Patients
Published in Experimental diabetes research (2012)“…Diabetic nephropathy (DN) is a long-term complication of diabetes mellitus that leads to end-stage renal disease. Microalbuminuria is used for the early…”
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