Search Results - "Kim, Ye Seon"

Contribution of p53 in sensitivity to EGFR tyrosine kinase inhibitors in non-small cell lung cancer by Jung, Sangyong, Kim, Dong Ha, Choi, Yun Jung, Kim, Seon Ye, Park, Hyojeong, Lee, Hyeonjeong, Choi, Chang-Min, Sung, Young Hoon, Lee, Jae Cheol, Rho, Jin Kyung

“…The emergence of resistance to epidermal growth factor receptor (EGFR) tyrosine kinase inhibitors (TKIs) in non-small cell lung cancer (NSCLC) with activating…”
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Exosomal PD-L1 promotes tumor growth through immune escape in non-small cell lung cancer by Kim, Dong Ha, Kim, HyeongRyul, Choi, Yun Jung, Kim, Seon Ye, Lee, Jung-Eun, Sung, Ki Jung, Sung, Young Hoon, Pack, Chan-Gi, Jung, Min-kyo, Han, Buhm, Kim, Kunhee, Kim, Woo Sung, Nam, Soo Jeong, Choi, Chang-Min, Yun, Miyong, Lee, Jae Cheol, Rho, Jin Kyung

“…Programmed cell death protein-1/programmed cell death ligand-1 (PD-1/PD-L1) pathway blockade is a promising new cancer therapy. Although PD-1/PD-L1 treatment…”
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MET and AXL Inhibitor NPS-1034 Exerts Efficacy against Lung Cancer Cells Resistant to EGFR Kinase Inhibitors Because of MET or AXL Activation by JIN KYUNG RHO, YUN JUNG CHOI, JAE CHEOL LEE, SEON YE KIM, TAE WON KIM, EUN KYUNG CHOI, YOON, Seon-Joo, BU MAN PARK, EUNHYE PARK, JONG HWAN BAE, CHOI, Chang-Min

“…In non-small cell lung cancer (NSCLC) with epidermal growth factor receptor (EGFR) mutations, acquired resistance to EGFR-tyrosine kinase inhibitors (EGFR-TKI)…”
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Enhanced Glycolysis Supports Cell Survival in EGFR-Mutant Lung Adenocarcinoma by Inhibiting Autophagy-Mediated EGFR Degradation by Kim, Ji Hye, Nam, Boas, Choi, Yun Jung, Kim, Seon Ye, Lee, Jung-Eun, Sung, Ki Jung, Kim, Woo Sung, Choi, Chang-Min, Chang, Eun-Ju, Koh, Jae Soo, Song, Joon Seon, Yoon, Shinkyo, Lee, Jae Cheol, Rho, Jin Kyung, Son, Jaekyoung

“…Oncogenic EGFR is essential for the development and growth of non-small cell lung cancer (NSCLC), but the precise roles of EGFR in lung cancer metabolism…”
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Natural Killer Cells as a Potential Biomarker for Predicting Immunotherapy Efficacy in Patients with Non-Small Cell Lung Cancer by Cho, Yong-Hee, Choi, Myeong Geun, Kim, Dong Ha, Choi, Yun Jung, Kim, Seon Ye, Sung, Ki Jung, Lee, Jae Cheol, Kim, Sang-Yeob, Rho, Jin Kyung, Choi, Chang-Min

“…Background Immunotherapy with immune checkpoint inhibitors for non-small cell lung cancer (NSCLC) has emerged as an important treatment option. Although…”
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Activation of the IGF1R pathway potentially mediates acquired resistance to mutant-selective 3rd-generation EGF receptor tyrosine kinase inhibitors in advanced non-small cell lung cancer by Park, Ji Hyun, Choi, Yun Jung, Kim, Seon Ye, Lee, Jung-Eun, Sung, Ki Jung, Park, Sojung, Kim, Woo Sung, Song, Joon Seon, Choi, Chang-Min, Sung, Young Hoon, Rho, Jin Kyung, Lee, Jae Cheol

“…Mutant-selective, 3rd-generation EGFR-TKIs were recently developed to control lung cancer cells harboring T790M-mediated resistance. However, the development…”
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AUY922 effectively overcomes MET- and AXL-mediated resistance to EGFR-TKI in lung cancer cells by Choi, Yun Jung, Kim, Seon Ye, So, Kwang Sup, Baek, In-Jeoung, Kim, Woo Sung, Choi, Se Hoon, Lee, Jae Cheol, Bivona, Trever G, Rho, Jin Kyung, Choi, Chang-Min

“…The activation of bypass signals, such as MET and AXL, has been identified as a possible mechanism of EGFR-TKI resistance. Because various oncoproteins depend…”
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Ethyl pyruvate stabilizes hypoxia-inducible factor 1 alpha via stimulation of the TCA cycle by Kim, Seon-Ye, Choi, Jae-Sun, Park, Chan, Jeong, Joo-Won

“…Abstract Ethyl pyruvate is a simple derivative of the endogenous metabolite pyruvate. Pyruvate is the starting substrate for the tricarboxylic acid (TCA) cycle…”
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Okadaic acid protects human neuroblastoma SH-SY5Y cells from 1-methyl-4-phenylpyridinium ion-induced apoptosis by Ahn, Kook-Hee, Kim, Young-Sun, Kim, Seon-Ye, Huh, Youngbuhm, Park, Chan, Jeong, Joo-Won

“…1-Methyl-4-phenylpyridinium ion (MPP +) has been shown to selectively inhibit mitochondrial function and induce a parkinsonism-like syndrome. MPP + stimulates…”
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Discovery of a Potent and Mutant-Selective EGFR Inhibitor that Overcomes T790M-Mediated Resistance in Lung Cancer by Kim, Dong Ha, Choi, Yun Jung, Kim, Seon Ye, Lee, Jung-Eun, Sung, Ki Jung, Sung, Young Hoon, Kim, Woo Sung, Kim, Sung-Eun, Ryu, Hyung Chul, Kim, Jae Sun, Guangying, Lu, Choi, Chang-Min, Rho, Jin Kyung, Lee, Jae Cheol

“…Background Despite remarkable activity in epidermal growth factor receptor (EGFR)-mutant lung cancer patients, the clinical efficacy of EGFR tyrosine kinase…”
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Okadaic acid promotes angiogenesis via activation of hypoxia-inducible factor-1 by Kim, Young-Sun, Ahn, Kook-Hee, Kim, Seon-Ye, Jeong, Joo-Won

“…Abstract Okadaic acid, a potent tumor promoter and an inhibitor of protein phosphatase 1 and 2A, has also been characterized as an angiogenic inducer in the…”
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Neuroendocrine differentiation in acquired resistance to epidermal growth factor receptor tyrosine kinase inhibitor by Chang, Youjin, Kim, Seon Ye, Choi, Yun Jung, So, Kwang Sup, Rho, Jin Kyung, Kim, Woo Sung, Lee, Jae Cheol, Chung, Jin-Haeng, Choi, Chang-Min

“…Small cell lung cancer (SCLC) transformation during epidermal growth factor receptor tyrosine kinase inhibitor (EGFR-TKI) treatment in lung cancer has been…”
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Isovaleric acid ameliorates ovariectomy‐induced osteoporosis by inhibiting osteoclast differentiation by Cho, Kwang Min, Kim, Ye Seon, Lee, Mingyu, Lee, Ha Young, Bae, Yoe‐Sik

“…Osteoclasts (OCs) play important roles in bone remodelling and contribute to bone loss by increasing bone resorption activity. Excessively activated OCs cause…”
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WKYMVm ameliorates obesity by improving lipid metabolism and leptin signalling by Kang, Ji Hyeon, Kim, Hyung Sik, Park, Seon Hyang, Kim, Ye Seon, Bae, Yoe‐Sik

“…Abstract Obesity is a metabolic disorder that results from an imbalance of energy intake and consumption. As low‐grade chronic inflammation caused by obesity…”
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Therapeutic effects of a phospholipase D1 inhibitor against polymicrobial sepsis by Bae, Yoe-Sik, Lee, Sung Kyun, Kim, Ye Seon, Lee, Ha Young

“…Abstract In this study, we found that a phospholipase D1-selective inhibitor (VU0155069), significantly increased survival rate against cecal ligation and…”
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CD200Rhigh neutrophils with dysfunctional autophagy establish systemic immunosuppression by increasing regulatory T cells by Kim, Ye Seon, Jeong, Yu Sun, Bae, Geon Ho, Kang, Ji Hyeon, Lee, Mingyu, Zabel, Brian A., Bae, Yoe-Sik

“…Distinct neutrophil populations arise during certain pathological conditions. The generation of dysfunctional neutrophils during sepsis and their contribution…”
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Unique characteristics of lung-resident neutrophils are maintained by PGE2/PKA/Tgm2-mediated signaling by Bae, Geon Ho, Kim, Ye Seon, Park, Ji Ye, Lee, Mingyu, Lee, Sung Kyun, Kim, Ji Cheol, Kim, Jang Gyu, Shin, Ye Ji, Lee, Ho, Kim, Soo-Youl, Bae, Yong-Soo, Zabel, Brian A., Kim, Hong Sook, Bae, Yoe-Sik

“…Lung-resident neutrophils need to be tightly regulated to avoid degranulation- and cytokine-associated damage to fragile alveolar structures that can lead to…”
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IM156, a new AMPK activator, protects against polymicrobial sepsis by Kang, Ji Hyeon, Lee, Sung Kyun, Yun, Nam Joo, Kim, Ye Seon, Song, Jason Jungsik, Bae, Yoe‐Sik

“…IM156, a novel biguanide with higher potency of AMP‐activated protein kinase activation than metformin, has inhibitory activity against angiogenesis and…”
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AKT/mTOR down-regulation by CX-4945, a CK2 inhibitor, promotes apoptosis in chemorefractory non-small cell lung cancer cells by So, Kwang Sup, Rho, Jin Kyung, Choi, Yun Jung, Kim, Seon Ye, Choi, Chang Min, Chun, Young Jin, Lee, Jae Cheol

“…The response to chemotherapeutic drugs in non-small cell lung cancer (NSCLC) is unsatisfactory, leading to poor outcomes. This study the aimed to investigates…”
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VU0155069 inhibits inflammasome activation independent of phospholipase D1 activity by Lee, Sung Kyun, Kim, Ye Seon, Bae, Geon Ho, Lee, Ha Young, Bae, Yoe-Sik

“…The inflammasome is a specialized multiprotein oligomer that regulates IL-1β production. Although regulation of the inflammasome is related to crucial…”
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