Search Results - "Kim, Taeg S."

Regulating the adaptive immune response to respiratory virus infection by Braciale, Thomas J., Sun, Jie, Kim, Taeg S.

“…Key Points The respiratory tract is a major portal of entry for viruses into the body. Infection of the respiratory tract can, if severe, induce…”
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Viral infection of the lung: Host response and sequelae by Yoo, Jae-Kwang, PhD, Kim, Taeg S., PhD, Hufford, Matthew M., PhD, Braciale, Thomas J., MD, PhD

“…Because of its essential role in gas exchange and oxygen delivery, the lung has evolved a variety of strategies to control inflammation and maintain…”
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Distinct Dendritic Cell Subsets Dictate the Fate Decision between Effector and Memory CD8+ T Cell Differentiation by a CD24-Dependent Mechanism by Kim, Taeg S., Gorski, Stacey A., Hahn, Steven, Murphy, Kenneth M., Braciale, Thomas J.

“…The contribution of different DC subsets to effector and memory CD8+ T cell generation during infection and the mechanism by which DCs controls these fate…”
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Alveolar Macrophages Prevent Lethal Influenza Pneumonia By Inhibiting Infection Of Type-1 Alveolar Epithelial Cells by Cardani, Amber, Boulton, Adam, Kim, Taeg S, Braciale, Thomas J

“…The Influenza A virus (IAV) is a major human pathogen that produces significant morbidity and mortality. To explore the contribution of alveolar macrophages…”
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Respiratory dendritic cell subsets differ in their capacity to support the induction of virus-specific cytotoxic CD8+ T cell responses by Kim, Taeg S, Braciale, Thomas J

“…Dendritic cells located at the body surfaces, e.g. skin, respiratory and gastrointestinal tract, play an essential role in the induction of adaptive immune…”
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The cell cycle time of CD8+ T cells responding in vivo is controlled by the type of antigenic stimulus by Yoon, Heesik, Kim, Taeg S, Braciale, Thomas J

“…A hallmark of cells comprising the mammalian adaptive immune system is the requirement for these rare naïve T (and B) lymphocytes directed to a specific…”
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Stress-associated erythropoiesis initiation is regulated by type 1 conventional dendritic cells by Kim, Taeg S, Hanak, Mark, Trampont, Paul C, Braciale, Thomas J

“…Erythropoiesis is an important response to certain types of stress, including hypoxia, hemorrhage, bone marrow suppression, and anemia, that result in…”
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Differential Response of Respiratory Dendritic Cell Subsets to Influenza Virus Infection by XUELI HAO, KIM, Taeg S, BRACIALE, Thomas J

“…Article Usage Stats Services JVI Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley…”
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IL-21R signaling suppresses IL-17+ gamma delta T cell responses and production of IL-17 related cytokines in the lung at steady state and after Influenza A virus infection by Moser, Emily K, Sun, Jie, Kim, Taeg S, Braciale, Thomas J

“…Influenza A virus (IAV) infection of the respiratory tract elicits a robust immune response, which is required for efficient virus clearance but at the same…”
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Detection and quantitation of eosinophils in the murine respiratory tract by flow cytometry by Stevens, Whitney W., Kim, Taeg S., Pujanauski, Lindsey M., Hao, Xueli, Braciale, Thomas J.

“…Traditionally, the identification and quantification of eosinophils in inflammatory tissues and exudates has been primarily based upon morphologic criteria and…”
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Unexpected phenotype of mice lacking Shcbp1, a protein induced during T cell proliferation by Buckley, Monica W, Arandjelovic, Sanja, Trampont, Paul C, Kim, Taeg S, Braciale, Thomas J, Ravichandran, Kodi S

“…T cell development and activation are highly regulated processes, and their proper execution is important for a competent immune system. Shc SH2-domain binding…”
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Viral Expression of CCL2 Is Sufficient To Induce Demyelination in RAG1−/− Mice Infected with a Neurotropic Coronavirus by KIM, Taeg S, PERLMAN, Stanley

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Antiviral CD8+ T cell effector activities in situ are regulated by target cell type by Hufford, Matthew M, Kim, Taeg S, Sun, Jie, Braciale, Thomas J

“…Cytotoxic T lymphocytes (CTLs) play a prominent role in the resolution of viral infections through their capacity both to mediate contact-dependent lysis of…”
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Antigen persistence and the control of local T cell memory by migrant respiratory dendritic cells after acute virus infection by Kim, Taeg S, Hufford, Matthew M, Sun, Jie, Fu, Yang-Xin, Braciale, Thomas J

“…Acute viral infections induce robust adaptive immune responses resulting in virus clearance. Recent evidence suggests that there may be depots of viral antigen…”
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Liver is able to activate naïve CD8+ T cells with dysfunctional anti-viral activity in the murine system by Lukens, John R, Dolina, Joseph S, Kim, Taeg S, Tacke, Robert S, Hahn, Young S

“…The liver possesses distinct tolerogenic properties because of continuous exposure to bacterial constituents and nonpathogenic food antigen. The central immune…”
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Enhanced Virulence Mediated by the Murine Coronavirus, Mouse Hepatitis Virus Strain JHM, Is Associated with a Glycine at Residue 310 of the Spike Glycoprotein by Ontiveros, Evelena, Kim, Taeg S, Gallagher, Thomas M, Perlman, Stanley

“…Article Usage Stats Services JVI Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley…”
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T cell responses during influenza infection: getting and keeping control by Kim, Taeg S, Sun, Jie, Braciale, Thomas J

“…The 2009 influenza pandemic highlighted the threat that type A influenza poses to human health. Thus, there is an urgency to understand the pathobiology of…”
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Liver-resident CD103+ dendritic cells prime antiviral CD8+ T cells in situ by Krueger, Peter D, Kim, Taeg S, Sung, Sun-Sang J, Braciale, Thomas J, Hahn, Young S

“…The liver maintains a tolerogenic environment to avoid unwarranted activation of its resident immune cells upon continuous exposure to food and bacterially…”
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The effector T cell response to influenza infection by Hufford, Matthew M, Kim, Taeg S, Sun, Jie, Braciale, Thomas J

“…Influenza virus infection induces a potent initial innate immune response, which serves to limit the extent of viral replication and virus spread. However,…”
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Maturation and Localization of Macrophages and Microglia During Infection with a Neurotropic Murine Coronavirus by Templeton, Steven P., Kim, Taeg S., O'Malley, Katherine, Perlman, Stanley

“…Macrophages and microglia are critical in the acute inflammatory response and act as final effector cells of demyelination during chronic infection with the…”
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