Search Results - "Kim, SoonJeung"

Plexin-Bs enhance their GAP activity with a novel activation switch loop generating a cooperative enzyme by Li, Zhen-lu, Müller-Greven, Jeannine, Kim, SoonJeung, Tamagnone, Luca, Buck, Matthias

“…Plexins receive guidance cues from semaphorin ligands and transmit their signal through the plasma membrane. This family of proteins is unique amongst…”
Get full text

Structure and Function of the Intracellular Region of the Plexin-B1 Transmembrane Receptor by Tong, Yufeng, Hota, Prasanta K., Penachioni, Junia Y., Hamaneh, Mehdi B., Kim, SoonJeung, Alviani, Rebecca S., Shen, Limin, He, Hao, Tempel, Wolfram, Tamagnone, Luca, Park, Hee-Won, Buck, Matthias

“…Members of the plexin family are unique transmembrane receptors in that they interact directly with Rho family small GTPases; moreover, they contain a…”
Get full text

Structural Basis of Rnd1 Binding to Plexin Rho GTPase Binding Domains (RBDs) by Wang, Hui, Hota, Prasanta K., Tong, Yufeng, Li, Buren, Shen, Limin, Nedyalkova, Lyudmila, Borthakur, Susmita, Kim, SoonJeung, Tempel, Wolfram, Buck, Matthias, Park, Hee-Won

“…Plexin receptors regulate cell adhesion, migration, and guidance. The Rho GTPase binding domain (RBD) of plexin-A1 and -B1 can bind GTPases, including Rnd1. By…”
Get full text

K-Ras G-domain binding with signaling lipid phosphatidylinositol (4,5)-phosphate (PIP2): membrane association, protein orientation, and function by Cao, Shufen, Chung, Stacey, Kim, SoonJeung, Li, Zhenlu, Manor, Danny, Buck, Matthias

“…Ras genes potently drive human cancers, with mutated proto-oncogene GTPase KRAS4B (K-Ras4B) being the most abundant isoform. Targeted inhibition of oncogenic…”
Get full text

Binding and Function of Phosphotyrosines of the Ephrin A2 (EphA2) Receptor Using Synthetic Sterile α Motif (SAM) Domains by Borthakur, Susmita, Lee, HyeongJu, Kim, SoonJeung, Wang, Bing-Cheng, Buck, Matthias

“…The sterile α motif (SAM) domain of the ephrin receptor tyrosine kinase, EphA2, undergoes tyrosine phosphorylation, but the effect of phosphorylation on the…”
Get full text

Biochemical and mutational analysis of intracellular regions of the Plexin‐B1 guidance receptor as a R‐RasGAP by Kim, SoonJeung, Hota, Prasanta K, Buck, Matthias

“…Plexins are single transmembrane receptors for semaphorin guidance cues, which regulate the cell motility through changes in the cells actin cytoskeleton…”
Get full text

Characterizing Plexin GTPase Interactions Using Gel Filtration, Surface Plasmon Resonance Spectrometry, and Isothermal Titration Calorimetry by Muller-Greven, Jeannine, Kim, SoonJeung, Hota, Prasanta K, Tong, Yufeng, Borthakur, Susmita, Buck, Matthias

“…Plexins are unique, as they are the first example of a transmembrane receptor that interacts directly with small GTPases, a family of proteins that are…”
Get more information

Molecular Basis of EPHA2 Pre-oligomers and the Inhibitory Function of Its SAM Domain by Shi, Xiaojun, Lingerak, Ryan, Yu, Chuan, Muller-Greven, Jeannine, Kim, SoonJeung, Gill-Rodriguez, Paloma, Raeselle Javier, Fatima, Bowman, Deanna, Hou, Yixuan, Ge, Yifan, Buck, Matthias, Wang, Bingcheng, Smith, Adam W.

Get full text

Eliciting neutralizing antibodies with gp120 outer domain constructs based on M-group consensus sequence by Qin, Yali, Banasik, Marisa, Kim, SoonJeung, Penn-Nicholson, Adam, Habte, Habtom H, LaBranche, Celia, Montefiori, David C, Wang, Chong, Cho, Michael W

“…Abstract One strategy being evaluated for HIV-1 vaccine development is focusing immune responses towards neutralizing epitopes on the gp120 outer domain (OD)…”
Get full text