Search Results - "Kim, Soon Hoe"

Protective effects of acetyl-L-carnitine on neurodegenarative changes in chronic cerebral ischemia models and learning-memory impairment in aged rats by Goo, Moon-Jung, Choi, Seul Min, Kim, Soon-Hoe, Ahn, Byoung Ok

“…This study investigated the effects of acetyl-L-carnitine (ALC) in secondarily-induced cerebral chronic ischemia models using rats with permanent ligation of…”
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DA-1229, a novel and potent DPP4 inhibitor, improves insulin resistance and delays the onset of diabetes by Kim, Mi-Kyung, Chae, Yu Na, Kim, Ha Dong, Yang, Eun Kyoung, Cho, Eun Jung, Choi, Song-hyen, Cheong, Ye-Hwang, Kim, Hae-Sun, Kim, Heung Jae, Jo, Yeong Woo, Son, Moon-Ho, Kim, Soon-Hoe, Shin, Chang Yell

“…To characterize the pharmacodynamic profile of DA-1229, a novel dipeptidyl peptidase (DPP) 4 inhibitor. Enzyme inhibition assays against DPP4, DPP8 and DPP9…”
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DA6034 promotes gastric epithelial cell migration and wound-healing through the mTOR pathway by Kim, Young Woo, Lee, Woo Hyung, Choi, Seul Min, Seo, Yoon Young, Ahn, Byoung Ok, Kim, Soon Hoe, Kim, Sang Geon

“…Background and Aim:  7‐Carboxymethyloxy‐3′,4′,5‐trimethoxy flavone (DA6034), a synthetic derivative of eupatilin, has a protective effect on gastric mucosa…”
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Discovery of DA-1229: A potent, long acting dipeptidyl peptidase-4 inhibitor for the treatment of type 2 diabetes by Kim, Heung Jae, Kwak, Woo Young, Min, Jong Pil, Lee, Jae Young, Yoon, Tae Hyun, Kim, Ha Dong, Shin, Chang Yell, Kim, Mi Kyung, Choi, Song Hyen, Kim, Hae Sun, Yang, Eun Kyoung, Cheong, Ye Hwang, Chae, Yu Na, Park, Kyung Jin, Jang, Ji Myun, Choi, Soo Jung, Son, Moon Ho, Kim, Soon Hoe, Yoo, Moohi, Lee, Bong Jin

“…The synthesis and SAR studies of β-amino amide DPP-4 inhibitor 5f are reported. A series of β-amino amide containing substituted piperazine-2-one derivatives…”
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Effect of DA-8031, a novel oral compound for premature ejaculation, on male rat sexual behavior by Kang, Kyung Koo, Sung, Ji Hyun, Kim, Soon Hoe, Lee, Sukhyang

“…Objectives DA‐8031 is a potent and selective serotonin transporter inhibitor developed for the treatment of premature ejaculation. The aim of the present study…”
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Dipeptidyl peptidase-4 inhibitor with β-amino amide scaffold: Synthesis, SAR and biological evaluation by Kim, Heung Jae, Kwak, Woo Young, Min, Jong Pil, Sung, Si Young, Kim, Ha Dong, Kim, Mi Kyung, Kim, Hae Sun, Park, Kyung Jin, Son, Moon Ho, Kim, Soon Hoe, Lee, Bong Jin

“…The SAR studies and evaluation of β-amino amide DPP4 inhibitor 5m are reported. Inhibitors of dipeptidyl peptidase-4 (DPP4) have been shown to be effective…”
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Candidate Molecule for Premature Ejaculation, DA-8031: In Vivo and In Vitro Characterization of DA-8031 by Jeon, Hyung-Jun, Kim, Hae-Sun, Lee, Chan-Ho, Lee, Young-Gun, Choi, Seol-Min, Sohn, Yong-Sung, Shin, Chang-Yong, Kim, Junghoon, Shim, Hyun-Joo, Kang, Kyung-Koo, Ahn, Byoung-Ok, Kim, Soon-Hoe

“…Objectives To evaluate the efficacy of DA-8031 against premature ejaculation, we performed in vitro and in vivo pharmacologic studies. Methods We used a…”
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Procyanidins in crataegus extract evoke endothelium-dependent vasorelaxation in rat aorta by Kim, Soon Hoe, Kang, Keon Wook, Kim, Kye Won, Kim, Nak Doo

“…The extract of Crataegus, a mixture of flavonoids and procyanidins extracted from hawthorn, Crataegus oxyacantha, L. and C. monogyna Jacq., relaxed vascular…”
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Investor sentiment from internet message postings and the predictability of stock returns by Kim, Soon-Ho, Kim, Dongcheol

“…By using an extensive dataset of more than 32 million messages on 91 firms posted on the Yahoo! Finance message board over the period January 2005 to December…”
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PAR-1622 is a selective peroxisome proliferator-activated receptor γ partial activator with preserved antidiabetic efficacy and broader safety profile for fluid retention by Kim, Mi-Kyung, Chae, Yu Na, Kim, Hae Sun, Choi, Song-hyen, Son, Moon Ho, Kim, Soon Hoe, Kim, Jin Kwan, Moon, Ho Sang, Park, Sang Kuk, Shin, Young Ah, Kim, Jae Gyu, Lee, Chun Ho, Lim, Joong In, Shin, Chang Yell

“…Peroxisome proliferator-activated receptor (PPAR) γ is known to be a key regulator of insulin resistance. PAR-1622 is a novel small molecule compound…”
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Mechanism of erectogenic effect of the selective phosphodiesterase type 5 inhibitor, DA-8159 by Doh, Hyounmie, Shin, Chang Yell, Son, Miwon, Ko, Jun Il, Yoo, Moohi, Kim, Soon Hoe, Kim, Won Bae

“…DA-8159, a new Phosphodiesterase (PDE) 5 inhibitor, has exhibited potent erectogenic potential in a penile erection test in rats and anesthetized dogs. In this…”
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DA-7911, $^{188}Rhenium-tin$ Colloid, as a New Therapeutic Agent of Rheumatoid Arthritis by Shin, Chang-Yell, Son, Miwon, Ko, Jun-Il, Jung, Mi-Young, Lee, In-Ki, Kim, Soon-Hoe, Kim, Won-Bae, Jeong, Jae-Min, Song, Yeong-Wook

“…Radiation synovectomy is one of the most useful methods for treating patients with refractory synovitis because of its convenience, long-term effects,…”
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Mechanism of Erectogenic Effect of the Selective Phosphodiesterase Type 5 Inhibitor, DA-8159 by Doh, Hyoun-Mie, Shin, Chang-Yell, Son, Mi-Won, Ko, Jun-Il, Yoo, Moo-Hi, Kim, Soon-Hoe, Kim, Won-Bae

“…OA-8159, a new Phosphodiesterase (PDE) 5 inhibitor, has exhibited potent erectogenic potential in a penile erection test in rats and anesthetized dogs. In this…”
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Inhibitory effect of DA-125, a new anthracyclin analog antitumor agent, on the invasion of human fibrosarcoma cells by down-regulating the matrix metalloproteinases by Park, Hyen Joo, Chung, Hwa-Jin, Min, Hye-Young, Park, Eun-Jung, Hong, Ji-Young, Kim, Won Bae, Kim, Soon Hoe, Lee, Sang Kook

“…Matrix metalloproteinases (MMPs), zinc-dependent proteolytic enzymes, play a pivotal role in tumor metastasis by cleavage of extracellular matrix as well as…”
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Anti-Diabetic Effects of DA-11004, a Synthetic IDPc Inhibitor in High Fat High Sucrose Diet-Fed C57BL/6J Mice by Shin, Chang-Yell, Jung, Mi-Young, Lee, In-Ki, Son, Mi-Won, Kim, Dong-Sung, Lim, Joong-In, Kim, Soon-Hoe, Yoo, Moo-Hi, Huh, Tae-Lin, Sohn, Young-Taek, Kim, Won-Bae

“…DA-11004 is a synthetic, potent NADP-dependent isocitrate dehydrogenase (IDPc) inhibitor where $IC_{50}$ for IDPc is 1.49 $\mu$M. The purpose of this study was…”
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Determination of a new phosphodiesterase V inhibitor, DA-8159, in plasma and urine by high-performance liquid chromatography by Shim, Hyun Joo, Lee, Eun Joo, Jung, Young Hee, Kim, So Hee, Kim, Soon Hoe, Yoo, Moohi, Kwon, Jong Won, Kim, Won Bae, Lee, Myung Gull

“…A high-performance liquid chromatographic (HPLC) method using liquid–liquid extraction for sample preparation was developed for the determination of a new…”
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Antipruritic Effect of DA-5018m A Capsaicin Derivative, in Mice by Kim, Dong-Hwan, Ahn, Byoung-Ok, Kim, Soon-Hoe, Kim, Won-Bae

“…The antipruritic effect of DA-5018m a capsaicin derivative, was examined in mice. Male ICR mice were topically pretreated with Zostrix-HP (0.075% capsaicin…”
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Studies on Protective Effect of Da-9601, Artemisia asiatica Extract, on Acetaminophen- and $CCI_{4}$induced Liver Damage in Rats by Ryu, Byoung-Kweon, Ahn, Byoung-Ok, Oh, Tae-Young, Kim, Soon-Hoe, Kim, Won-Bae, Lee, Eun-Bang

“…The hepatoprotective effect of DA-9601, a quality-controlled extract of artemisisa asiatica, on liver damage induced by acetaminophen (APAP) and carbon…”
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Protective Effect of DA-9601, an Extract of Artemisiae Herba, against Naproxen-induced Gastric Damage in Arthritic Rats by Oh, Tae-Young, Ryu, Byong-Kweon, Ko, Jun-Il, Ahn, Byoung-Ok, Kim, Soon-Hoe, Kim, Won-Bae, Lee, Eun-Bang, Jin, Joo-Hyun, Hahm, Ki-Baik

“…Gastrointestinal irritation is the most frequent adverse effect in patients chronically taking nonsteroidal antiinflammatory drugs (NSAIDs) for the treatment…”
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Metabolism of eupatilin in rats using liquid chromatography/electrospray mass spectrometry by Ji, Hye Young, Lee, Hye Won, Shim, Hyun Joo, Kim, Soon Hoe, Kim, Won Bae, Lee, Hye Suk

“…Eupatilin (5,7‐dihydroxy‐3′,4′,6‐trimethoxyflavone) is an active ingredient of an ethanol extract of Artemisia asiatica (DA‐9601) that is used in the treatment…”
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