Search Results - "Kim, Seongho"

The Intersection of Metabolomics and Data Science by Kim, Seongho

“…Metabolomics generates a vast amount of data and heavily relies on data science for biological interpretation [...]…”
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US-GAN: Ultrasound Image-Specific Feature Decomposition for Fine Texture Transfer by Kim, Seongho, Song, Byung Cheol

“…Ultrasound images acquired through various measuring devices may have different styles, and each style may be specialized for diagnosing specific diseases…”
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Comparative analysis of mass spectral matching-based compound identification in gas chromatography–mass spectrometry by Koo, Imhoi, Kim, Seongho, Zhang, Xiang

“…•Compared performance of 5 literature-reported compound identification measures.•Estimated dependency of identification accuracy on the size of reference…”
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Protein Expression and Functional Relevance of Efflux and Uptake Drug Transporters at the Blood–Brain Barrier of Human Brain and Glioblastoma by Bao, Xun, Wu, Jianmei, Xie, Youming, Kim, Seongho, Michelhaugh, Sharon, Jiang, Jun, Mittal, Sandeep, Sanai, Nader, Li, Jing

“…The knowledge of transporter protein expression and function at the human blood–brain barrier (BBB) is critical to prediction of drug BBB penetration and…”
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Inconspicuous longitudinal tears of the intracranial vertebral artery in traumatic basal subarachnoid hemorrhage by Kim, Seongho

“…Blunt force trauma to the head or neck region can cause traumatic basal subarachnoid hemorrhage (TBSAH), which can result in rapid loss of consciousness and…”
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A Phase 0 Trial of Ribociclib in Recurrent Glioblastoma Patients Incorporating a Tumor Pharmacodynamic- and Pharmacokinetic-Guided Expansion Cohort by Tien, An-Chi, Li, Jing, Bao, Xun, Derogatis, Alanna, Kim, Seongho, Mehta, Shwetal, Sanai, Nader

“…CDK4/6-dependent cell-cycle regulation is disrupted in most glioblastomas. This study assesses the central nervous system (CNS) pharmacokinetics and tumor…”
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iMatch2: Compound identification using retention index for analysis of gas chromatography–mass spectrometry data by Koo, Imhoi, Shi, Xue, Kim, Seongho, Zhang, Xiang

“…•Improving compound identification accuracy using retention indices in NIST11.•Statistical test shows that column class is the most affected mean difference…”
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Wavelet- and Fourier-Transform-Based Spectrum Similarity Approaches to Compound Identification in Gas Chromatography/Mass Spectrometry by Koo, Imhoi, Zhang, Xiang, Kim, Seongho

“…The high-throughput gas chromatography/mass spectrometry (GC/MS) technology offers a powerful means of analyzing a large number of chemical and biological…”
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Clinical association of progesterone receptor isoform A with breast cancer metastasis consistent with its unique mechanistic role in preclinical models by Rosati, Rayna, Oppat, Kailey, Huang, Yanfang, Kim, Seongho, Ratnam, Manohar

“…Luminal breast cancer (L-BCa) comprises the majority of incurable, distally metastatic breast cancer cases. Estrogen supports growth of L-BCa cells but…”
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Evaluation of two-stage designs of Phase 2 single-arm trials in glioblastoma: a systematic review by Yoo, Wonsuk, Kim, Seongho, Garcia, Michael, Mehta, Shwetal, Sanai, Nader

“…Due to economical and ethical reasons, the two-stage designs have been widely used for Phase 2 single-arm trials in oncology because the designs allow us to…”
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High-performance self-powered wireless sensor node driven by a flexible thermoelectric generator by Kim, Yong Jun, Gu, Hyun Mo, Kim, Choong Sun, Choi, Hyeongdo, Lee, Gyusoup, Kim, Seongho, Yi, Kevin K., Lee, Sang Gug, Cho, Byung Jin

“…As industrial environments expand and become more automated, wireless sensor networks are attracting attention as an essential technology for efficient…”
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Toward Identity-Invariant Facial Expression Recognition: Disentangled Representation via Mutual Information Perspective by Kim, Daeha, Kim, Seongho, Song, Byung Cheol

“…This paper presents an identity-invariant facial expression recognition framework. It aims to make a facial expression recognition (FER) model independently…”
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Phosphatidylethanolamines Are Associated with Nonalcoholic Fatty Liver Disease (NAFLD) in Obese Adults and Induce Liver Cell Metabolic Perturbations and Hepatic Stellate Cell Activation by Shama, Samaa, Jang, Hyejeong, Wang, Xiaokun, Zhang, Yang, Shahin, Nancy Nabil, Motawi, Tarek Kamal, Kim, Seongho, Gawrieh, Samer, Liu, Wanqing

“…Pathogenesis roles of phospholipids (PLs) in nonalcoholic fatty liver disease (NAFLD) remain incompletely understood. This study investigated the role of PLs…”
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A method of finding optimal weight factors for compound identification in gas chromatography―mass spectrometry by KIM, Seongho, KOO, Imhoi, XIAOLI WEI, XIANG ZHANG

“…The compound identification in gas chromatography-mass spectrometry (GC-MS) is achieved by matching the experimental mass spectrum to the mass spectra in a…”
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Pharmacological targeting of CXCL12/CXCR4 signaling in prostate cancer bone metastasis by Conley-LaComb, M Katie, Semaan, Louie, Singareddy, Rajareddy, Li, Yanfeng, Heath, Elisabeth I, Kim, Seongho, Cher, Michael L, Chinni, Sreenivasa R

“…The CXCL12/CXCR4 axis transactivates HER2 and promotes intraosseous tumor growth. To further explore the transactivation of HER2 by CXCL12, we investigated the…”
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Fatty acid desaturase 1 (FADS1) is a cancer marker for patient survival and a potential novel target for precision cancer treatment by Heravi, Gioia, Jang, Hyejeong, Wang, Xiaokun, Long, Ze, Peng, Zheyun, Kim, Seongho, Liu, Wanqing

“…Fatty Acid Desaturase-1 (FADS1) or delta 5 desaturase (D5D) is a rate-limiting enzyme involved in the biosynthesis of long-chain polyunsaturated fatty acids…”
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Profiling of Polar Metabolites in Mouse Feces Using Four Analytical Platforms to Study the Effects Of Cathelicidin-Related Antimicrobial Peptide in Alcoholic Liver Disease by He, Liqing, Li, Fengyuan, Yin, Xinmin, Bohman, Patrick, Kim, Seongho, McClain, Craig J, Feng, Wenke, Zhang, Xiang

“…Alterations in gut bacterial homeostasis result in changes in intestinal metabolites. To investigate the effects of alcohol on fecal metabolites and the role…”
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Neutrophil lymphocyte ratio and duration of prior anti-angiogenic therapy as biomarkers in metastatic RCC receiving immune checkpoint inhibitor therapy by Jeyakumar, Ghayathri, Kim, Seongho, Bumma, Naresh, Landry, Craig, Silski, Cynthia, Suisham, Stacey, Dickow, Brenda, Heath, Elisabeth, Fontana, Joseph, Vaishampayan, Ulka

“…There is an unmet need to determine factors predictive of clinical benefit, to guide therapeutic sequencing and selection in metastatic RCC (mRCC). We…”
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Cetuximab PET delineated changes in cellular distribution of EGFR upon dasatinib treatment in triple negative breast cancer by McKnight, Brooke N, Kim, Seongho, Boerner, Julie L, Viola, Nerissa T

“…At least 50% of triple negative breast cancer (TNBC) overexpress the epidermal growth factor receptor, EGFR, which paved the way for clinical trials…”
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Adaptor proteins mediate CXCR4 and PI4KA crosstalk in prostate cancer cells and the significance of PI4KA in bone tumor growth by Govindarajan, Barani, Sbrissa, Diego, Pressprich, Mark, Kim, Seongho, Rishi, Arun K., Vaishampayan, Ulka, Cher, Michael L., Chinni, Sreenivasa R.

“…The chemokine receptor, CXCR4 signaling regulates cell growth, invasion, and metastasis to the bone-marrow niche in prostate cancer (PCa). Previously, we…”
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