Search Results - "Kim, Seong M."

PTEN Deficiency and AMPK Activation Promote Nutrient Scavenging and Anabolism in Prostate Cancer Cells by Kim, Seong M, Nguyen, Tricia T, Ravi, Archna, Kubiniok, Peter, Finicle, Brendan T, Jayashankar, Vaishali, Malacrida, Leonel, Hou, Jue, Robertson, Jane, Gao, Dong, Chernoff, Jonathan, Digman, Michelle A, Potma, Eric O, Tromberg, Bruce J, Thibault, Pierre, Edinger, Aimee L

“…We report that PTEN-deficient prostate cancer cells use macropinocytosis to survive and proliferate under nutrient stress. PTEN loss increased macropinocytosis…”
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Attacking the supply wagons to starve cancer cells to death by Selwan, Elizabeth M., Finicle, Brendan T., Kim, Seong M., Edinger, Aimee L.

“…The constitutive anabolism of cancer cells not only supports proliferation but also addicts tumor cells to a steady influx of exogenous nutrients. Limiting…”
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Checkpoint Regulation of Nuclear Tos4 Defines S Phase Arrest in Fission Yeast by Kim, Seong M, Tripathi, Vishnu P, Shen, Kuo-Fang, Forsburg, Susan L

“…From yeast to humans, the cell cycle is tightly controlled by regulatory networks that regulate cell proliferation and can be monitored by dynamic visual…”
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A high dose KRP203 induces cytoplasmic vacuoles associated with altered phosphoinositide segregation and endosome expansion by Kofuji, Satoshi, Wolfe, Kara, Sumita, Kazutaka, Kageyama, Shun, Yoshino, Hirofumi, Hirota, Yoshihisa, Ogawa-Iio, Aki, Kanoh, Hirotaka, Sasaki, Mika, Kofuji, Kaori, Davis, Mindy I., Pragani, Rajan, Shen, Min, Boxer, Matthew B., Nakatsu, Fubito, Nigorikawa, Kiyomi, Sasaki, Takehiko, Takeuchi, Koh, Senda, Toshiya, Kim, Seong M., Edinger, Aimee L., Simeonov, Anton, Sasaki, Atsuo T.

“…In animal cells, vacuoles are absent, but can be induced by diseases and drugs. While phosphoinositides are critical for membrane trafficking, their role in…”
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Targeting cancer metabolism by simultaneously disrupting parallel nutrient access pathways by Kim, Seong M, Roy, Saurabh G, Chen, Bin, Nguyen, Tiffany M, McMonigle, Ryan J, McCracken, Alison N, Zhang, Yanling, Kofuji, Satoshi, Hou, Jue, Selwan, Elizabeth, Finicle, Brendan T, Nguyen, Tricia T, Ravi, Archna, Ramirez, Manuel U, Wiher, Tim, Guenther, Garret G, Kono, Mari, Sasaki, Atsuo T, Weisman, Lois S, Potma, Eric O, Tromberg, Bruce J, Edwards, Robert A, Hanessian, Stephen, Edinger, Aimee L

“…Oncogenic mutations drive anabolic metabolism, creating a dependency on nutrient influx through transporters, receptors, and macropinocytosis. While…”
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Effective quality factors of multimodal interaction in simple and complex tasks of using a smart television by Kim, Seong M., Jung, Eui S., Park, Jaekyu

“…Influencing quality factors, related to the user and system, need to be considered when building a well-designed multimodal interaction system. User groups,…”
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Effects of stereochemistry, saturation, and hydrocarbon chain length on the ability of synthetic constrained azacyclic sphingolipids to trigger nutrient transporter down-regulation, vacuolation, and cell death by Perryman, Michael S., Tessier, Jérémie, Wiher, Timothy, O’Donoghue, Heather, McCracken, Alison N., Kim, Seong M., Nguyen, Dean G., Simitian, Grigor S., Viana, Matheus, Rafelski, Susanne, Edinger, Aimee L., Hanessian, Stephen

“…[Display omitted] Constrained analogs containing a 2-hydroxymethylpyrrolidine core of the natural sphingolipids sphingosine, sphinganine,…”
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shl, a New Set of Arabidopsis Mutants with Exaggerated Developmental Responses to Available Red, Far-Red, and Blue Light by Pepper, Alan E., Mi-seon Seong-Kim, Stephanie M. Hebst, Kathryn N. Ivey, Su-Jin Kwak, Denise E. Broyles

“…The interaction of light perception with development is the subject of intensive genetic analysis in the model plant Arabidopsis. We performed genetic screens…”
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Phosphorylation of a constrained azacyclic FTY720 analog enhances anti-leukemic activity without inducing S1P receptor activation by McCracken, A N, McMonigle, R J, Tessier, J, Fransson, R, Perryman, M S, Chen, B, Keebaugh, A, Selwan, E, Barr, S A, Kim, S M, Roy, S G, Liu, G, Fallegger, D, Sernissi, L, Brandt, C, Moitessier, N, Snider, A J, Clare, S, Müschen, M, Huwiler, A, Kleinman, M T, Hanessian, S, Edinger, A L

“…The frequency of poor outcomes in relapsed leukemia patients underscores the need for novel therapeutic approaches. The Food and Drug Administration-approved…”
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Effect of gain expansion of MMIC power amplifier for high order modulation OFDM portable system by Kim, Joon H., Jeong, J.H., Kim, S.M., Kim, Ji H., Park, C.S., Lee, K.C.

“…We propose a realistic complex output behavior of MMIC HBT power amplifier having the gain expansion effect for high order modulation M-QAM OFDM portable…”
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Loss of TSC2 confers resistance to ceramide and nutrient deprivation by Guenther, G G, Liu, G, Ramirez, M U, McMonigle, R J, Kim, S M, McCracken, A N, Joo, Y, Ushach, I, Nguyen, N L, Edinger, A L

“…Nutrient stress that produces quiescence and catabolism in normal cells is lethal to cancer cells, because oncogenic mutations constitutively drive anabolism…”
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Microporation is a valuable transfection method for efficient gene delivery into human umbilical cord blood-derived mesenchymal stem cells by Lim, Jung Yeon, Park, Sun Hwa, Jeong, Chang Hyun, Oh, Ji Hyeon, Kim, Seong Muk, Ryu, Chung Hun, Park, Soon A, Ahn, Jae Geun, Oh, Wonil, Jeun, Sin-Soo, Chang, Jong Wook

“…Mesenchymal stem cells (MSCs) are an attractive source of adult stem cells for therapeutic application in clinical study. Genetic modification of MSCs with…”
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Occurrence rate and fate of competitive flow of the left internal thoracic artery used in Y-composite graftsCentral MessagePerspective by Ji Seong Kim, MD, PhD, Yoonjin Kang, MD, Suk Ho Sohn, MD, Ho Young Hwang, MD, PhD

“…Objectives: We evaluated the occurrence rate of competitive flow and the fate of grafts of left internal thoracic artery (LITA)-to-left anterior descending…”
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ω-3 fatty acid-enriched parenteral nutrition shortens hospital stay in acute variceal bleeding cirrhotic patients by Kim, Seong-Jung, Chun, In Ae, Cho, Ju-Yeon, Lee, Jun Hyung, Lee, Jun, Kim, Young-Dae, Park, Chan-Guk

“…Acute variceal bleeding, a crucial complication of liver cirrhosis requires high energy expenditures but gastrointestinal bleeding limits enteral feeding in…”
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Use of polyvinyl acetal spears for the treatment of ingrown nails with trichloroacetic acid matricectomy by Kwon, Soyoung, Kim, Seong Rae, Park, Hyunsun

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Echocardiographic Predictors of Progression to Persistent or Permanent Atrial Fibrillation in Patients with Paroxysmal Atrial Fibrillation (E6P Study) by Yoon, Yeonyee E., MD, Oh, Il-Young, MD, Kim, Sung-Ai, MD, Park, Kyoung-Ha, MD, Kim, Seong Hwan, MD, Park, Jae-Hyeong, MD, Kim, Jeong-Eun, MD, Lee, Seung-Pyo, MD, Kim, Hyung-Kwan, MD, Kim, Yong-Jin, MD, Sohn, Dae-Won, MD, Cho, Goo-Yeong, MD, PhD

“…Backgrounds Paroxysmal atrial fibrillation (AF) frequently, but not always, progresses to persistent/permanent AF. The aim of this study was to evaluate the…”
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GFR and Cardiovascular Outcomes After Acute Myocardial Infarction: Results From the Korea Acute Myocardial Infarction Registry by Bae, Eun Hui, MD, PhD, Lim, Sang Yup, MD, PhD, Cho, Kyung Hoon, MD, Choi, Joon Seok, MD, Kim, Chang Seong, MD, Park, Jeong Woo, MD, PhD, Ma, Seong Kwon, MD, PhD, Jeong, Myung Ho, MD, PhD, Kim, Soo Wan, MD, PhD

“…Background Despite strong evidence linking decreased glomerular filtration rate (GFR) to worse outcomes, the impact of GFR on mortality and morbidity in…”
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Increased Risk of Herpes Zoster in Children with Asthma: A Population-Based Case-Control Study by Kim, Bong-Seong, MD, Mehra, Sonia, MD, Yawn, Barbara, MD, Grose, Charles, MD, Tarrell, Robert, BS, Lahr, Brian, MS, Juhn, Young J., MD, MPH

“…Objective To determine the risk of herpes zoster (HZ) in children with and without asthma. Study design This study was designed as a population-based…”
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The -238 tumor necrosis factor-α promoter polymorphism is associated with decreased susceptibility to cancers by Jang, Won Hee, Yang, Young-Il, Yea, Sung Su, Lee, Youn Jae, Chun, Jin Ho, Kim, Hyeong-In, Kim, Mi Seong, Paik, Kye-Hyung

“…We investigated the potential association of tumor necrosis factor-α (TNF-α) promoter polymorphisms with cancers. The study included 169 patients with gastric…”
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5.64 ANALYSIS OF FACTORS THAT INFLUENCE SMARTPHONE EXPOSURE AND USE FROM AGES 3 TO 5 YEARS by Kim, Seong Ju, MD, Shin, Yunmi, MD, Jo, Woo Dong, MD

“…Objectives: The aim of the present study was to examine young children's exposure to and use of mobile media devices including smartphone and identify parental…”
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