Search Results - "Kim, Seok‐Jo"

ROS-induced ROS release orchestrated by Nox4, Nox2, and mitochondria in VEGF signaling and angiogenesis by Kim, Young-Mee, Kim, Seok-Jo, Tatsunami, Ryosuke, Yamamura, Hisao, Fukai, Tohru, Ushio-Fukai, Masuko

“…Reactive oxygen species (ROS) derived from NADPH oxidase (NOX) and mitochondria play a critical role in growth factor-induced switch from a quiescent to an…”
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SIRT3 deficiency promotes lung fibrosis by augmenting alveolar epithelial cell mitochondrial DNA damage and apoptosis by Jablonski, Renea P., Kim, Seok‐Jo, Cheresh, Paul, Williams, David B., Morales‐Nebreda, Luisa, Cheng, Yuan, Yeldandi, Anjana, Bhorade, Sangeeta, Pardo, Annie, Selman, Moises, Ridge, Karen, Gius, David, Scott Budinger, G. R., Kamp, David W.

“…ABSTRACT Alveolar epithelial cell (AEC) mitochondrial dysfunction and apoptosis are important in idiopathic pulmonary fibrosis and asbestosis. Sirtuin 3…”
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SIRT3 Overexpression Ameliorates Asbestos-Induced Pulmonary Fibrosis, mt-DNA Damage, and Lung Fibrogenic Monocyte Recruitment by Cheresh, Paul, Kim, Seok-Jo, Jablonski, Renea, Watanabe, Satoshi, Lu, Ziyan, Chi, Monica, Helmin, Kathryn A, Gius, David, Budinger, G R Scott, Kamp, David W

“…Alveolar epithelial cell (AEC) mitochondrial (mt) DNA damage and fibrotic monocyte-derived alveolar macrophages (Mo-AMs) are implicated in the pathobiology of…”
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The Role of Mitochondrial DNA in Mediating Alveolar Epithelial Cell Apoptosis and Pulmonary Fibrosis by Kim, Seok-Jo, Cheresh, Paul, Jablonski, Renea P, Williams, David B, Kamp, David W

“…Convincing evidence has emerged demonstrating that impairment of mitochondrial function is critically important in regulating alveolar epithelial cell (AEC)…”
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Mitochondria-targeted Ogg1 and Aconitase-2 Prevent Oxidant-induced Mitochondrial DNA Damage in Alveolar Epithelial Cells by Kim, Seok-Jo, Cheresh, Paul, Williams, David, Cheng, Yuan, Ridge, Karen, Schumacker, Paul T., Weitzman, Sigmund, Bohr, Vilhelm A., Kamp, David W.

“…Mitochondria-targeted human 8-oxoguanine DNA glycosylase (mt-hOgg1) and aconitase-2 (Aco-2) each reduce oxidant-induced alveolar epithelial cell (AEC)…”
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Hypercapnia increases airway smooth muscle contractility via caspase-7-mediated miR-133a-RhoA signaling by Shigemura, Masahiko, Lecuona, Emilia, Angulo, Martín, Homma, Tetsuya, Rodríguez, Diego A, Gonzalez-Gonzalez, Francisco J, Welch, Lynn C, Amarelle, Luciano, Kim, Seok-Jo, Kaminski, Naftali, Budinger, G R Scott, Solway, Julian, Sznajder, Jacob I

“…The elevation of carbon dioxide (CO ) in tissues and the bloodstream (hypercapnia) occurs in patients with severe lung diseases, including chronic obstructive…”
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The Sphingosine Kinase 1 Inhibitor, PF543, Mitigates Pulmonary Fibrosis by Reducing Lung Epithelial Cell mtDNA Damage and Recruitment of Fibrogenic Monocytes by Cheresh, Paul, Kim, Seok-Jo, Huang, Long Shuang, Watanabe, Satoshi, Joshi, Nikita, Williams, Kinola J N, Chi, Monica, Lu, Ziyan, Harijith, Anantha, Yeldandi, Anjana, Lam, Anna P, Gottardi, Cara, Misharin, Alexander V, Budinger, G R Scott, Natarajan, Viswanathan, Kamp, David W

“…Idiopathic pulmonary fibrosis (IPF) is a chronic disease for which novel approaches are urgently required. We reported increased sphingosine kinase 1 (SPHK1)…”
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Critical role of endothelial hydrogen peroxide in post-ischemic neovascularization by Urao, Norifumi, Sudhahar, Varadarajan, Kim, Seok-Jo, Chen, Gin-Fu, McKinney, Ronald D, Kojda, Georg, Fukai, Tohru, Ushio-Fukai, Masuko

“…Reactive oxygen species (ROS) play an important role in angiogenesis in endothelial cells (ECs) in vitro and neovascularization in vivo. However, little is…”
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Novel role of p66Shc in ROS-dependent VEGF signaling and angiogenesis in endothelial cells by Oshikawa, Jin, Kim, Seok-Jo, Furuta, Eiji, Caliceti, Cristiana, Chen, Gin-Fu, McKinney, Ronald D, Kuhr, Frank, Levitan, Irena, Fukai, Tohru, Ushio-Fukai, Masuko

“…p66Shc, a longevity adaptor protein, is demonstrated as a key regulator of reactive oxygen species (ROS) metabolism involved in aging and cardiovascular…”
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Asbestos-induced alveolar epithelial cell apoptosis. The role of endoplasmic reticulum stress response by Kamp, David W, Liu, Gang, Cheresh, Paul, Kim, Seok-Jo, Mueller, Amanda, Lam, Anna P, Trejo, Humberto, Williams, David, Tulasiram, Sandhya, Baker, Margaret, Ridge, Karen, Chandel, Navdeep S, Beri, Rohinee

“…Asbestos exposure results in pulmonary fibrosis (asbestosis) and malignancies (bronchogenic lung cancer and mesothelioma) by mechanisms that are not fully…”
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The ganglioside GM3 is associated with cisplatin-induced apoptosis in human colon cancer cells by Chung, Tae-Wook, Choi, Hee-Jung, Kim, Seok-Jo, Kwak, Choong-Hwan, Song, Kwon-Ho, Jin, Un-Ho, Chang, Young-Chae, Chang, Hyeun Wook, Lee, Young-Choon, Ha, Ki-Tae, Kim, Cheorl-Ho

“…Cisplatin (cis-diamminedichloroplatinum, CDDP) is a well-known chemotherapeutic agent for the treatment of several cancers. However, the precise mechanism…”
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Asbestos-induced pulmonary fibrosis is augmented in 8-oxoguanine DNA glycosylase knockout mice by Cheresh, Paul, Morales-Nebreda, Luisa, Kim, Seok-Jo, Yeldandi, Anjana, Williams, David B, Cheng, Yuan, Mutlu, Gökhan M, Budinger, G R Scott, Ridge, Karen, Schumacker, Paul T, Bohr, Vilhelm A, Kamp, David W

“…Asbestos causes asbestosis and malignancies by mechanisms that are not fully established. Alveolar epithelial cell (AEC) injury and repair are crucial…”
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Localized cysteine sulfenic acid formation by vascular endothelial growth factor: role in endothelial cell migration and angiogenesis by Kaplan, Nihal, Urao, Norifumi, Furuta, Eiji, Kim, Seok-Jo, Razvi, Masooma, Nakamura, Yoshimasa, McKinney, Ronald D, Poole, Leslie B, Fukai, Tohru, Ushio-Fukai, Masuko

“…Reactive oxygen species (ROS) are important mediators for VEGF receptor 2 (VEGFR2) signalling involved in angiogenesis. The initial product of Cys oxidation,…”
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Oxidative stress and pulmonary fibrosis by Cheresh, Paul, Kim, Seok-Jo, Tulasiram, Sandhya, Kamp, David W.

“…Oxidative stress is implicated as an important molecular mechanism underlying fibrosis in a variety of organs, including the lungs. However, the causal role of…”
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Gut microbe-derived metabolite trimethylamine N-oxide activates PERK to drive fibrogenic mesenchymal differentiation by Kim, Seok-Jo, Bale, Swarna, Verma, Priyanka, Wan, Qianqian, Ma, Feiyang, Gudjonsson, Johann E., Hazen, Stanley L., Harms, Paul W., Tsou, Pei-Suen, Khanna, Dinesh, Tsoi, Lam C., Gupta, Nilaksh, Ho, Karen J., Varga, John

“…Intestinal dysbiosis is prominent in systemic sclerosis (SSc), but it remains unknown how it contributes to microvascular injury and fibrosis that are…”
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Ganglioside GM3 inhibits VEGF/VEGFR-2-mediated angiogenesis: Direct interaction of GM3 with VEGFR-2 by Chung, Tae-Wook, Kim, Seok-Jo, Choi, Hee-Jung, Kim, Keuk-Jun, Kim, Mi-Jin, Kim, Sung-Hoon, Lee, Hyo-Jeong, Ko, Jeong-Heon, Lee, Young-Choon, Suzuki, Akemi, Kim, Cheorl-Ho

“…Angiogenesis is associated with growth, invasion, and metastasis of human solid tumors. Aberrant activation of endothelial cells and induction of microvascular…”
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Ganglioside GM3 participates in the TGF-β1-induced epithelial-mesenchymal transition of human lens epithelial cells by Kim, Seok-Jo, Chung, Tae-Wook, Choi, Hee-Jung, Kwak, Choong-Hwan, Song, Kwon-Ho, Suh, Seok-Jong, Kwon, Kyung-Min, Chang, Young-Chae, Park, Young-Guk, Chang, Hyeun Wook, Kim, Kyoung-Sook, Kim, Cheorl-Ho, Lee, Young-Choon

“…TGF-β (transforming growth factor-β)-induced EMT (epithelial-mesenchymal transition) induces the proliferation and migration of the HLE (human lens epithelial)…”
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Fermented Viola mandshurica Inhibits Melanogenesis in B16 Melanoma Cells by KWAK, Yeon-Joo, KIM, Kyoung-Sook, KIM, Kyung-Mi, YU, Hai Yang, CHUNG, Eunsook, KIM, Seok-Jo, CHA, Jae-Young, LEE, Young-Choon, LEE, Jai-Heon

“…We assessed the effects of chloroform extract of fermented Viola mandshurica (CEFV) on melanogenesis B16 melanoma cells. CEFV treatment significantly decreased…”
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Triphenylmethane Reductase from Citrobacter sp. Strain KCTC 18061P: Purification, Characterization, Gene Cloning, and Overexpression of a Functional Protein in Escherichia coli by JANG, Moon-Sun, LEE, Young-Mi, KIM, Cheorl-Ho, LEE, Jai-Heon, KANG, Dong-Woo, KIM, Seok-Jo, LEE, Young-Choon

“…Classifications Services AEM Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley Reddit…”
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Sialyllactose suppresses angiogenesis by inhibiting VEGFR-2 activation, and tumor progression by Chung, Tae-Wook, Kim, Eun-Young, Kim, Seok-Jo, Choi, Hee-Jung, Jang, Se Bok, Kim, Keuk-Jun, Ha, Sun-Hyung, Abekura, Fukushi, Kwak, Choong-Hwan, Kim, Cheorl-Ho, Ha, Ki-Tae

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