Search Results - "Kim, Seo Yihl"
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BNIP3L/NIX-mediated mitophagy protects against glucocorticoid-induced synapse defects
Published in Nature communications (20-01-2021)“…Stress-induced glucocorticoids disturb mitochondrial bioenergetics and dynamics; however, instead of being removed via mitophagy, the damaged mitochondria…”
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High Glucose-Induced Reactive Oxygen Species Stimulates Human Mesenchymal Stem Cell Migration Through Snail and EZH2-Dependent E-Cadherin Repression
Published in Cellular physiology and biochemistry (01-05-2018)“…Background/Aims: Glucose plays an important role in stem cell fate determination and behaviors. However, it is still not known how glucose contributes to the…”
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Urolithin A suppresses high glucose-induced neuronal amyloidogenesis by modulating TGM2-dependent ER-mitochondria contacts and calcium homeostasis
Published in Cell death and differentiation (01-01-2021)“…Hyperglycemia in diabetes mellitus (DM) patients is a causative factor for amyloidogenesis and induces neuropathological changes, such as impaired neuronal…”
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BICD1 mediates HIF1α nuclear translocation in mesenchymal stem cells during hypoxia adaptation
Published in Cell death and differentiation (01-09-2019)“…Hypoxia inducible factor 1α (HIF1α) is a master regulator leading to metabolic adaptation, an essential physiological process to maintain the survival of stem…”
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Ethanol-activated CaMKII signaling induces neuronal apoptosis through Drp1-mediated excessive mitochondrial fission and JNK1-dependent NLRP3 inflammasome activation
Published in Cell communication and signaling (12-08-2020)“…Neurodegeneration is a representative phenotype of patients with chronic alcoholism. Ethanol-induced calcium overload causes NOD-like receptor protein 3…”
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Sodium butyrate inhibits high cholesterol-induced neuronal amyloidogenesis by modulating NRF2 stabilization-mediated ROS levels: involvement of NOX2 and SOD1
Published in Cell death & disease (18-06-2020)“…The gut–brain axis is currently being studied as a therapeutic strategy for neurological diseases, especially Alzheimer’s disease (AD). Obesity results in the…”
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High glucose‐mediated PICALM and mTORC1 modulate processing of amyloid precursor protein via endosomal abnormalities
Published in British journal of pharmacology (01-08-2020)“…Background and Purpose Although diabetes mellitus (DM) is an important risk factor for Alzheimer's disease (AD), the detailed mechanism(s) by which DM…”
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O-cyclic phytosphingosine-1-phosphate stimulates HIF1α-dependent glycolytic reprogramming to enhance the therapeutic potential of mesenchymal stem cells
Published in Cell death & disease (05-08-2019)“…O-cyclic phytosphingosine-1-phosphate (cP1P) is a novel chemically synthesized sphingosine metabolite derived from phytosphingosine-1-phosphate. Although…”
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Mycobacterium avium Modulates the Protective Immune Response in Canine Peripheral Blood Mononuclear Cells
Published in Frontiers in cellular and infection microbiology (14-01-2021)“…, an opportunistic intracellular pathogen, is a member of the non-tuberculous mycobacteria species. causes respiratory disease in immunosuppressed individuals…”
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Melatonin activates ABCA1 via the BiP/NRF1 pathway to suppress high-cholesterol-induced apoptosis of mesenchymal stem cells
Published in Stem cell research & therapy (05-02-2021)“…Retarded wound healing in patients with obesity contributes to a risk of complications associated with vascular insufficiency and oxidative stress. The high…”
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Serum protein profiling of lung, pancreatic, and colorectal cancers reveals alcohol consumption-mediated disruptions in early-stage cancer detection
Published in Heliyon (01-12-2022)“…While the link between serum proteins and cancer has been studied in an effort to enable early-stage cancer detection, factors that might perturb this link has…”
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PICALM- and mTORC1-mediated early endosomal disturbance upregulates Aβ generation under high glucose conditions
Published in IBRO reports (01-09-2019)Get full text
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