Search Results - "Kim, Se Nyun"
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Chromosomal instability determines taxane response
Published in Proceedings of the National Academy of Sciences - PNAS (26-05-2009)“…Microtubule-stabilizing (MTS) agents, such as taxanes, are important chemotherapeutics with a poorly understood mechanism of action. We identified a set of…”
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Caspase-mediated Cdk2 activation is a critical step to execute transforming growth factor-β1-induced apoptosis in human gastric cancer cells
Published in Oncogene (08-03-2001)“…Although TGF-β1, a growth inhibitor, is known to also induce apoptosis, the molecular mechanism of this apoptosis is largely undefined. Here, we identify the…”
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MED16 and MED23 of Mediator Are Coactivators of Lipopolysaccharide- and Heat-Shock-Induced Transcriptional Activators
Published in Proceedings of the National Academy of Sciences - PNAS (17-08-2004)“…Transcriptional activators interact with diverse proteins and recruit transcriptional machinery to the activated promoter. Recruitment of the Mediator complex…”
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Type II and III Taste Bud Cells Preferentially Expressed Kainate Glutamate Receptors in Rats
Published in The Korean journal of physiology & pharmacology (01-01-2009)“…Glutamate-induced cobalt uptake reveals that non-NMDA glutamate receptors (GluRs) are present in rat taste bud cells. Previous studies involving glutamate…”
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5
A molecular basis for embryo apposition at the luminal epithelium
Published in Molecular and cellular endocrinology (30-04-2004)“…To obtain a gene expression profile during embryo apposition to the luminal epithelium, we isolated mouse luminal epithelium from implantation (IM) and…”
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Signal-Induced Transcriptional Activation by Dif Requires the dTRAP80 Mediator Module
Published in Molecular and Cellular Biology (01-02-2003)“…Article Usage Stats Services MCB Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley…”
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Type II and III Taste Bud Cells Preferentially Expressed Kainate Glutamate Receptors in Rats
Published in The Korean journal of physiology & pharmacology (01-12-2009)“…Glutamate-induced cobalt uptake reveals that non-NMDA glutamate receptors (GluRs) are present in rat taste bud cells. Previous studies involving glutamate…”
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8
Age-dependent changes of gene expression in the Drosophila head
Published in Neurobiology of aging (01-07-2005)“…Previous gene expression profiling studies in Drosophila have provided clues for understanding the aging process at the gene expression level. For a detailed…”
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8-CL-camp induces cell cycle-specific apoptosis in human cancer cells
Published in International journal of cancer (01-07-2001)Get full text
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10
Participation of type II protein kinase A in the retinoic acid-induced growth inhibition of SH-SY5Y human neuroblastoma cells
Published in Journal of cellular physiology (01-03-2000)“…To examine the role of protein kinase A (EC 2.7.1.37) isozymes in the retinoic acid‐induced growth inhibition and neuronal differentiation, we investigated the…”
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The RIIβ Regulatory Subunit of Protein Kinase A Binds to cAMP Response Element: An Alternative cAMP Signaling Pathway
Published in Proceedings of the National Academy of Sciences - PNAS (09-06-1998)“…cAMP, through the activation of cAMP-dependent protein kinase (PKA), is involved in transcriptional regulation. In eukaryotic cells, cAMP is not considered to…”
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cDNA microarray gene expression profiling of hydroxyurea, paclitaxel, and p-anisidine, genotoxic compounds with differing tumorigenicity results
Published in Environmental and molecular mutagenesis (2003)“…The potential application of toxicogenomics to predictive toxicology has been discussed widely, but the utility of the approach remains largely unproven. Using…”
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Downregulation of lipopolysaccharide response in drosophila by negative crosstalk between the AP1 and NF-κB signaling modules
Published in Nature immunology (01-02-2005)“…I Kappa B kinase (IKK) and Jun N-terminal kinase (Jnk) signaling modules are important in the synthesis of immune effector molecules during innate immune…”
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14
Abstract 3841: HIF-143, a novel inhibitor of complex III, inhibits pancreatic cancer growth by suppressing reactive oxygen species production and epidermal growth factor signal
Published in Cancer research (Chicago, Ill.) (15-04-2012)“…Abstract Reactive oxygen species have been considered as a therapeutic target for cancer treatment. In this study, we characterized the anticancer activity of…”
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Downregulation of lipopolysaccharide response in Drosophila by negative crosstalk between the AP1 and NF-kappaB signaling modules
Published in Nature immunology (01-02-2005)“…IkappaB kinase (IKK) and Jun N-terminal kinase (Jnk) signaling modules are important in the synthesis of immune effector molecules during innate immune…”
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Downregulation of lipopolysaccharide response in drosophila by negative crosstalk between the AP1 and NF-[kappa]B signaling modules
Published in Nature immunology (01-02-2005)“…IkappaB kinase (IKK) and Jun N-terminal kinase (Jnk) signaling modules are important in the synthesis of immune effector molecules during innate immune…”
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17
Dual Anticancer Activity of 8-Cl-cAMP: Inhibition of Cell Proliferation and Induction of Apoptotic Cell Death
Published in Biochemical and biophysical research communications (05-07-2000)“…8-Cl-cAMP induces apoptotic cell death in human cancer cells. To look at this more closely, we examined the changes in the levels of Bcl-2 family proteins…”
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Caspase-mediated Cdk2 activation is a critical step to execute transforming growth factor-[beta]1-induced apoptosis in human gastric cancer cells
Published in Oncogene (08-03-2001)“…Although TGF-beta1, a growth inhibitor, is known to also induce apoptosis, the molecular mechanism of this apoptosis is largely undefined. Here, we identify…”
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19
8‐Cl‐cAMP induces cell cycle‐specific apoptosis in human cancer cells
Published in International journal of cancer (01-07-2001)“…8‐Cl‐cyclic adenosine monophosphate (8‐Cl‐cAMP) has been known to induce growth inhibition and differentiation in a variety of cancer cells by differential…”
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Ala99ser mutation in RI[alpha] Regulatory Subunit of protein kinase A causes reduced kinase activation by cAMP and arrest of hormone-dependent breast cancer cell growth
Published in Molecular and cellular biochemistry (01-05-1999)“…Expression of the RIα regulatory subunit of protein kinase A type I is increased in human cancer cell lines, in primary tumors, in cells after transformation,…”
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