Search Results - "Kim, Sangwoo"
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B Cells Improve Overall Survival in HPV-Associated Squamous Cell Carcinomas and Are Activated by Radiation and PD-1 Blockade
Published in Clinical cancer research (01-07-2020)“…To characterize the role of B cells on human papilloma virus (HPV)-associated cancer patient outcomes and determine the effects of radiation and PD-1 blockade…”
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Numerical methodology to evaluate unipolar saturation current limit of DC corona discharge in complex geometries
Published in Scientific reports (22-08-2022)“…The unipolar saturation current limit ( I sat ) gives an upper limit to the corona current that can be obtained from a unipolar corona discharge. Therefore, it…”
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Role of B Cells in Responses to Checkpoint Blockade Immunotherapy and Overall Survival of Cancer Patients
Published in Clinical cancer research (15-11-2021)“…The role of B cells in the tumor microenvironment and B-cell-mediated antitumor immune responses remains relatively understudied. Recent seminal studies have…”
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BAMixChecker: an automated checkup tool for matched sample pairs in NGS cohort
Published in Bioinformatics (01-11-2019)“…Abstract Summary Mislabeling in the process of next generation sequencing is a frequent problem that can cause an entire genomic analysis to fail, and a…”
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Immune Modulation of Head and Neck Squamous Cell Carcinoma and the Tumor Microenvironment by Conventional Therapeutics
Published in Clinical cancer research (15-07-2019)“…Head and neck squamous cell carcinoma (HNSCC) accounts for more than 600,000 cases and 380,000 deaths annually worldwide. Although human papillomavirus…”
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Physical interpretation of entropy, Boltzmann constant, and temperature
Published in Scientific reports (31-07-2024)“…Through the previously reported the quantum-identity, the light-model, and the T (temperature) · S (entropy) energy, the implied meaning of temperature and…”
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Isoform specific gene expression analysis of KRAS in the prognosis of lung adenocarcinoma patients
Published in BMC bioinformatics (19-02-2018)“…Aberrant mutations in KRAS play a critical role in tumor initiation and progression, and are a negative prognosis factor in lung adenocarcinoma (LUAD). Using…”
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Brain somatic mutations observed in Alzheimer’s disease associated with aging and dysregulation of tau phosphorylation
Published in Nature communications (12-07-2019)“…The role of brain somatic mutations in Alzheimer’s disease (AD) is not well understood. Here, we perform deep whole-exome sequencing (average read depth 584×)…”
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Brain somatic mutations in MTOR cause focal cortical dysplasia type II leading to intractable epilepsy
Published in Nature medicine (01-04-2015)“…Deep sequencing identifies somatic activating mutations of MTOR in affected brain regions of FCDII patients that are sufficient to cause neuronal migration…”
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10
Decoration of CuO NWs Gas Sensor with ZnO NPs for Improving NO2 Sensing Characteristics
Published in Sensors (Basel, Switzerland) (17-03-2021)“…This paper introduces a method for improving the sensitivity to NO2 gas of a p-type metal oxide semiconductor gas sensor. The gas sensor was fabricated using…”
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11
Study on the applicability of regression models and machine learning models for predicting concrete compressive strength
Published in Structural engineering and mechanics (25-09-2024)“…Accurately predicting the strength of concrete is vital for ensuring the safety and durability of structures, thereby contributing to time and cost savings…”
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Early Improved Functional Outcomes in Head and Neck Cancer Patients with Primary Tumor Detection
Published in The Laryngoscope (01-02-2024)“…Objectives We characterize functional outcomes in head and neck cancer of unknown primary (CUP) based on primary site identification. Methods In this…”
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De novo somatic mutations in components of the PI3K-AKT3-mTOR pathway cause hemimegalencephaly
Published in Nature genetics (01-08-2012)“…Joseph Gleeson and colleagues report exome sequencing of 20 individuals with hemimegalencephaly (HME), identifying de novo somatic mutations in the PIK3CA ,…”
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Impact of mouse contamination in genomic profiling of patient-derived models and best practice for robust analysis
Published in Genome Biology (11-11-2019)“…Patient-derived xenograft and cell line models are popular models for clinical cancer research. However, the inevitable inclusion of a mouse genome in a…”
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Pluronic F-68 and F-127 Based Nanomedicines for Advancing Combination Cancer Therapy
Published in Pharmaceutics (01-08-2023)“…Pluronics are amphiphilic triblock copolymers composed of two hydrophilic poly (ethylene oxide) (PEO) chains linked via a central hydrophobic polypropylene…”
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Conformational Chaperones for Structural Studies of Membrane Proteins Using Antibody Phage Display with Nanodiscs
Published in Structure (London) (02-02-2016)“…A major challenge in membrane biophysics is to define the mechanistic linkages between a protein's conformational transitions and its function. We describe a…”
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Structural basis for activation of voltage sensor domains in an ion channel TPC1
Published in Proceedings of the National Academy of Sciences - PNAS (25-09-2018)“…Voltage-sensing domains (VSDs) couple changes in transmembrane electrical potential to conformational changes that regulate ion conductance through a central…”
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Cross-species oncogenic signatures of breast cancer in canine mammary tumors
Published in Nature communications (17-07-2020)“…Genomic and precision medicine research has afforded notable advances in human cancer treatment, yet applicability to other species remains uncertain. Through…”
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Human papillomavirus E5 suppresses immunity via inhibition of the immunoproteasome and STING pathway
Published in Cell reports (Cambridge) (30-05-2023)“…The role that human papillomavirus (HPV) oncogenes play in suppressing responses to immunotherapy in cancer deserves further investigation. In particular, the…”
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Somatic Mutations in TSC1 and TSC2 Cause Focal Cortical Dysplasia
Published in American journal of human genetics (02-03-2017)“…Focal cortical dysplasia (FCD) is a major cause of the sporadic form of intractable focal epilepsies that require surgical treatment. It has recently been…”
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