Search Results - "Kim, Samuel"
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Tumor Burden and Immunotherapy: Impact on Immune Infiltration and Therapeutic Outcomes
Published in Frontiers in immunology (01-02-2021)“…Cancer immunotherapy has revolutionized the treatment landscape in medical oncology, but its efficacy has been variable across patients. Biomarkers to predict…”
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Single-Cell RT-PCR in Microfluidic Droplets with Integrated Chemical Lysis
Published in Analytical chemistry (Washington) (16-01-2018)“…Droplet microfluidics can identify and sort cells using digital reverse transcription polymerase chain reaction (RT-PCR) signals from individual cells…”
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Outcomes of extracorporeal membrane oxygenation following the 2018 adult heart allocation policy
Published in PloS one (20-05-2022)“…The purpose of the study was to characterize changes in waitlist and post-transplant outcomes of extracorporeal membrane oxygenation (ECMO) patients bridged to…”
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Comparative Evaluation of Genetically Encoded Voltage Indicators
Published in Cell reports (Cambridge) (15-01-2019)“…Imaging voltage using fluorescent-based sensors could be an ideal technique to probe neural circuits with high spatiotemporal resolution. However, due to…”
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The Two Koreas and the Great Powers
Published 26-06-2006“…This book explores Korea's place in terms of multiple levels and domains of interaction pertaining to foreign-policy behaviors and relations with the four…”
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Abseq: Ultrahigh-throughput single cell protein profiling with droplet microfluidic barcoding
Published in Scientific reports (14-03-2017)“…Proteins are the primary effectors of cellular function, including cellular metabolism, structural dynamics, and information processing. However, quantitative…”
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Unhealthy Lifestyle and Gut Dysbiosis: A Better Understanding of the Effects of Poor Diet and Nicotine on the Intestinal Microbiome
Published in Frontiers in endocrinology (Lausanne) (08-06-2021)“…The study of the intestinal or gut microbiome is a newer field that is rapidly gaining attention. Bidirectional communication between gut microbes and the host…”
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Extracting Interpretable Physical Parameters from Spatiotemporal Systems Using Unsupervised Learning
Published in Physical review. X (11-09-2020)“…Experimental data are often affected by uncontrolled variables that make analysis and interpretation difficult. For spatiotemporal systems, this problem is…”
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Characteristics and outcomes of lung transplants performed with ex-situ lung perfusion
Published in The Journal of heart and lung transplantation (01-02-2024)“…Ex-situ lung perfusion (ESLP) can be used to assess and rehabilitate donor lungs, potentially expanding the donor pool. We examined the characteristics and…”
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Particle-Templated Emulsification for Microfluidics-Free Digital Biology
Published in Analytical chemistry (Washington) (21-08-2018)“…The compartmentalization of reactions in monodispersed droplets is valuable for applications across biology. However, the requirement of microfluidics to…”
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Microdroplet fusion mass spectrometry for fast reaction kinetics
Published in Proceedings of the National Academy of Sciences - PNAS (31-03-2015)“…We investigated the fusion of high-speed liquid droplets as a way to record the kinetics of liquid-phase chemical reactions on the order of microseconds. Two…”
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Ovarian and Uterine Functions in Female Survivors of Childhood Cancers
Published in The oncologist (Dayton, Ohio) (01-02-2018)“…Adult survivors of childhood cancers are more prone to developing poor reproductive and obstetrical outcomes than their siblings and the general population as…”
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Opening Holes in the Blanket of Inhibition: Localized Lateral Disinhibition by VIP Interneurons
Published in The Journal of neuroscience (23-03-2016)“…Inhibitory interneurons in the neocortex often connect in a promiscuous and extensive fashion, extending a "blanket of inhibition" on the circuit. This raises…”
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Population-specific causal disease effect sizes in functionally important regions impacted by selection
Published in Nature communications (17-02-2021)“…Many diseases exhibit population-specific causal effect sizes with trans-ethnic genetic correlations significantly less than 1, limiting trans-ethnic polygenic…”
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Association of center-level temporary mechanical circulatory support use and waitlist outcomes after the 2018 adult heart allocation policy
Published in Surgery (01-09-2022)“…The present study characterizes the association of center-level temporary mechanical circulatory support use with waitlist outcomes after the 2018 adult heart…”
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Deep Learning and Symbolic Regression for Discovering Parametric Equations
Published in IEEE transaction on neural networks and learning systems (01-11-2024)“…Symbolic regression is a machine learning technique that can learn the equations governing data and thus has the potential to transform scientific discovery…”
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Center Volume Impacts Readmissions and Mortality after Congenital Cardiac Surgery
Published in The Journal of pediatrics (01-01-2022)“…To characterize the relationship between surgical volume and postoperative outcomes in congenital heart surgery, we used a national cohort to assess the costs,…”
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SEQUIN Multiscale Imaging of Mammalian Central Synapses Reveals Loss of Synaptic Connectivity Resulting from Diffuse Traumatic Brain Injury
Published in Neuron (Cambridge, Mass.) (22-07-2020)“…The brain’s complex microconnectivity underlies its computational abilities and vulnerability to injury and disease. It has been challenging to illuminate the…”
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Rewiring cancer drivers to activate apoptosis
Published in Nature (London) (10-08-2023)“…Genes that drive the proliferation, survival, invasion and metastasis of malignant cells have been identified for many human cancers 1 – 4 . Independent…”
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