Search Results - "Kim, Peter G"
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Induction of Multipotential Hematopoietic Progenitors from Human Pluripotent Stem Cells via Respecification of Lineage-Restricted Precursors
Published in Cell stem cell (03-10-2013)“…Human pluripotent stem cells (hPSCs) represent a promising source of patient-specific cells for disease modeling, drug screens, and cellular therapies…”
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TET2-mutant clonal hematopoiesis and risk of gout
Published in Blood (08-09-2022)“…Gout is a common inflammatory arthritis caused by precipitation of monosodium urate (MSU) crystals in individuals with hyperuricemia. Acute flares are…”
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Effect of Developmental Stage of HSC and Recipient on Transplant Outcomes
Published in Developmental cell (09-06-2014)“…The first hematopoietic stem cells (HSCs) that engraft irradiated adult mice arise in the aorta-gonad-mesonephros (AGM) on embryonic day 11.5 (E11.5). However,…”
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Adenosine signaling promotes hematopoietic stem and progenitor cell emergence
Published in The Journal of experimental medicine (04-05-2015)“…Hematopoietic stem cells (HSCs) emerge from aortic endothelium via the endothelial-to-hematopoietic transition (EHT). The molecular mechanisms that initiate…”
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Notch1 acts via Foxc2 to promote definitive hematopoiesis via effects on hemogenic endothelium
Published in Blood (26-02-2015)“…Hematopoietic and vascular development share many common features, including cell surface markers and sites of origin. Recent lineage-tracing studies have…”
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Hematopoietic stem cells develop in the absence of endothelial cadherin 5 expression
Published in Blood (24-12-2015)“…Rare endothelial cells in the aorta-gonad-mesonephros (AGM) transition into hematopoietic stem cells (HSCs) during embryonic development. Lineage tracing…”
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The Association between Clonal Hematopoiesis and Gout
Published in Blood (23-11-2021)“…▪ Background: Gout is a highly prevalent arthritis associated with debilitating joint pain and functional impairment. It is caused by elevated serum uric acid…”
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Clonal hematopoiesis and risk of chronic liver disease
Published in Nature (London) (01-04-2023)“…Chronic liver disease is a major public health burden worldwide 1 . Although different aetiologies and mechanisms of liver injury exist, progression of chronic…”
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Author Correction: Clonal haematopoiesis and risk of chronic liver disease
Published in Nature (London) (20-07-2023)Get full text
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Variations in incidence, overall survival, and cytogenetic risk in patients of white and Korean ethnicity with acute myeloid leukemia in the United States
Published in Journal of clinical oncology (20-05-2016)“…Abstract only…”
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Outcomes of older acute myeloid leukemia (AML) patients receiving hypomethylating therapy versus standard induction chemotherapy (IC) prior to allogeneic hematopoietic cell transplantation (HCT)
Published in Journal of clinical oncology (20-05-2016)“…Abstract only…”
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12
Induction of multipotential hematopoietic progenitors from human pluripotent stem cells via re-specification of lineage-restricted precursors
Published in Cell stem cell (03-10-2013)“…Human pluripotent stem cells (hPSCs) represent a promising source of patient-specific cells for disease modeling, drug screens, and cellular therapies…”
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Scl and Notch Act Downstream of Hedgehog Signaling to Promote Embryonic Hematopoiesis From Endothelial Cells
Published in Blood (18-11-2011)“…Abstract 1283 Adult hematopoietic cells transition through a hemogenic endothelial (HE) intermediate during development, but the signaling pathways modulating…”
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