Search Results - "Kim, Nick K"

Synthesis of trans-(3S)-Amino-(4R)-alkyl- and -(4S)-Aryl-piperidines via Ring-Closing Metathesis Reaction by Hu, X. Eric, Kim, Nick K, Ledoussal, Benoit

“…trans-(3S)-Amino piperidines bearing various alkyl and aryl substituents at the C-4 position were synthesized via a ring-closing metathesis reaction. The…”
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Discovery of (3S)-Amino-(4R)-ethylpiperidinyl Quinolones as Potent Antibacterial Agents with a Broad Spectrum of Activity and Activity against Resistant Pathogens by Hu, X. Eric, Kim, Nick K, Gray, Jeffrey L, Almstead, Ji-In K, Seibel, William L, Ledoussal, Benoit

“…Novel quinolone antibacterial agents bearing (3S)-amino-(4R)-ethylpiperidines were designed by using low energy conformation analysis and synthesized by…”
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Regio- and stereo-controlled copper organometallic addition to a piperidinyl aziridine: synthesis of trans 3-amino-4-alkyl-piperidines by Hu, X.Eric, Kim, Nick K, Ledoussal, Benoit, Colson, Anny-Odile

“…3,4-Piperidinyl aziridine N-phosphonate underwent ring opening in Grignard addition catalyzed by a copper reagent to yield trans 3-amino-4-alkyl-piperidines…”
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Synthesis and biological testing of non-Fluorinated analogues of levofloxacin by Gray, Jeffrey L., Almstead, Ji-In K., Gallagher, Corey P., Hu, X.Eric, Kim, Nick K., Taylor, Cynthia J., Twinem, Tracy L., Wallace, Cynthia D., Ledoussal, Benoit

“…Quinolones without the usual 6-fluorine substituent have been recently described as potent antibacterial agents. A series of non-fluorinated analogues of the…”
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