Search Results - "Kim, Nathaniel"

Silane and Germane Molecular Electronics by Su, Timothy A, Li, Haixing, Klausen, Rebekka S, Kim, Nathaniel T, Neupane, Madhav, Leighton, James L, Steigerwald, Michael L, Venkataraman, Latha, Nuckolls, Colin

“…This Account provides an overview of our recent efforts to uncover the fundamental charge transport properties of Si–Si and Ge–Ge single bonds and introduce…”
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The role of retrobulbar and retinal circulation on optic nerve head and retinal nerve fibre layer structure in patients with open-angle glaucoma over an 18-month period by Tobe, Leslie Abrams, Harris, Alon, Hussain, Rehan M, Eckert, George, Huck, Andrew, Park, Joshua, Egan, Patrick, Kim, Nathaniel J, Siesky, Brent

“…Evidence suggests that vascular abnormalities play a role in the pathogenesis of open-angle glaucoma (OAG) in some patients. This study aims to assess changes…”
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Multiplexed Nanoflares: mRNA Detection in Live Cells by Prigodich, Andrew E, Randeria, Pratik S, Briley, William E, Kim, Nathaniel J, Daniel, Weston L, Giljohann, David A, Mirkin, Chad A

“…We report the development of the multiplexed nanoflare, a nanoparticle agent that is capable of simultaneously detecting two distinct mRNA targets inside a…”
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High-Conductance Pathways in Ring-Strained Disilanes by Way of Direct σ‑Si–Si to Au Coordination by Kim, Nathaniel T, Li, Haixing, Venkataraman, Latha, Leighton, James L

“…A highly conducting electronic contact between a strained disilane and Au is demonstrated through scanning tunneling microscope-based single-molecule…”
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Development of a histone deacetylase 6 inhibitor and its biological effects by Lee, Ju-Hee, Mahendran, Adaickapillai, Yao, Yuanshan, Ngo, Lang, Venta-Perez, Gisela, Choy, Megan L., Kim, Nathaniel, Ham, Won-Seok, Breslow, Ronald, Marks, Paul A.

“…Development of isoform-selective histone deacetylase (HDAC) inhibitors is important in elucidating the function of individual HDAC enzymes and their potential…”
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Mechanism for Si–Si Bond Rupture in Single Molecule Junctions by Li, Haixing, Kim, Nathaniel T, Su, Timothy A, Steigerwald, Michael L, Nuckolls, Colin, Darancet, Pierre, Leighton, James L, Venkataraman, Latha

“…The stability of chemical bonds can be studied experimentally by rupturing single molecule junctions under applied voltage. Here, we compare voltage-induced…”
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Nanotechnology and glaucoma: a review of the potential implications of glaucoma nanomedicine by Kim, Nathaniel J, Harris, Alon, Gerber, Austin, Tobe, Leslie Abrams, Amireskandari, Annahita, Huck, Andrew, Siesky, Brent

“…The purpose of this review is to discuss the evolution of nanotechnology and its potential diagnostic and therapeutic applications in the field of…”
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Quantitation of propofol metabolites by LC–MS/MS demonstrating long detection window for urine drug monitoring by Rosano, Thomas G., Wood, Michelle, Scholz, Kiley L., Whitely, Kiera, Kim, Nathaniel, Ehlers, Melissa

“…•The chromatographic method is useful in propofol analysis.•It uses a dilute-and-analyze sample preparation.•The method has a linear calibration model.•It can…”
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Targeting Transforming Growth Factor-β Signaling in Primary Open-Angle Glaucoma by Wang, Jenny, Harris, Alon, Prendes, Mark A, Alshawa, Loor, Gross, Josh C, Wentz, Scott M, Rao, Ambika B, Kim, Nathaniel J, Synder, Alexander, Siesky, Brent

“…Transforming growth factor-β (TGF-β) may play a role in the pathogenesis of primary open-angle glaucoma (POAG). Elevated levels of TGF-β are found in the…”
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Antiproliferative activities of halogenated thieno[3,2-d]pyrimidines by Temburnikar, Kartik W., Zimmermann, Sarah C., Kim, Nathaniel T., Ross, Christina R., Gelbmann, Christopher, Salomon, Christine E., Wilson, Gerald M., Balzarini, Jan, Seley-Radtke, Katherine L.

“…The in vitro evaluation of thieno[3,2-d]pyrimidines identified halogenated compounds 1 and 2 with antiproliferative activity against three different cancer…”
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Effects of MS-153 on chronic ethanol consumption and GLT1 modulation of glutamate levels in male alcohol-preferring rats by Alhaddad, Hasan, Kim, Nathaniel T, Aal-Aaboda, Munaf, Althobaiti, Yusuf S, Leighton, James, Boddu, Sai H S, Wei, Yangjie, Sari, Youssef

“…We have recently shown that upregulation of glutamate transporter 1 (GLT1) in the brain is associated in part with reduction in ethanol intake in…”
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Patella Strength Characteristics in Cemented vs Press-fit Implants: A Biomechanical Analysis of Initial Stability by Patel, Akshar H., Wilder, J. Heath, Weldy, John M., Ross, Bailey J., Kim, Nathaniel E., Wang, Hao, Sanchez, Fernando L., Sherman, William F.

“…Patellar resurfacing is routinely performed during total knee arthroplasty to reduce pain associated with patellofemoral osteoarthritis. With 3-dimensional…”
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Novel therapies for open-angle glaucoma by Wentz, Scott M, Kim, Nathaniel J, Wang, Jenny, Amireskandari, Annahita, Siesky, Brent, Harris, Alon

“…Open-angle glaucoma is a multifactorial optic neuropathy characterized by progressive loss of retinal ganglion cells and their axons. It is an irreversible…”
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Retinal oxygen saturation and metabolism: how does it pertain to glaucoma? An update on the application of retinal oximetry in glaucoma by Tobe, Leslie A, Harris, Alon, Schroeder, Anne, Gerber, Austin, Holland, Stephen, Amireskandari, Annahita, Kim, Nathaniel J, Siesky, Brent

“…To discuss the techniques and mechanisms of retinal oximetry with a focus on utilization of retinal oximetry in the assessment of retinal oxygen saturation in…”
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Comparison of intraocular pressure in glaucoma subjects treated with Xalatan® versus generic latanoprost by Egan, Patrick, Harris, Alon, Siesky, Brent, Abrams‐Tobe, Leslie, Gerber, Austin L., Park, Joshua, Holland, Steven, Kim, Nathaniel J., Januleviciene, Ingrida

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"Reverse" Carbocyclic Fleximers: Synthesis of a New Class of Adenosine Deaminase Inhibitors by Zimmermann, Sarah C., Sadler, Joshua M., O'Daniel, Peter I., Kim, Nathaniel T., Seley-Radtke, Katherine L.

“…A series of flexible carbocyclic pyrimidine nucleosides has been designed and synthesized. In contrast to previously reported "fleximers" from our laboratory,…”
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Determination of Toxoplasma gondii Replication in Naïve and Activated Macrophages by Swati Goyal, Brian Lynch, Nathaniel Kim, Emma Iaconetti

“…Toxoplasma gondii is an obligate intracellular protozoan parasite that causes the disease toxoplasmosis. Chronic infection is established through the formation…”
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TMET-20. A METABOLIC BIOMARKER IN GLIOBLASTOMA: A PROMISING APPLICATION OF CO-POLARIZED [1-13C]PYRUVATE AND [1-13C]DEHYDROASCORBATE by Coffee, Elizabeth, Porcari, Paola, Kim, Nathaniel, Patel, Saket, Berishaj, Marjan, Deh, Kofi, Rahimi-Keshari, Kayvan

“…Abstract BACKGROUND Noninvasive biomarkers for treatment response in glioblastoma are needed to improve patient outcomes. Our understanding of redox biology in…”
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6,6'-2 H2 fructose as a deuterium metabolic imaging probe in liver cancer by Zhang, Guannan, Cullen, Quinlan, Berishaj, Marjan, Deh, Kofi, Kim, Nathaniel, Keshari, Kayvan R

“…Hepatocellular carcinoma (HCC) is one of the leading causes of cancer-related deaths. Imaging plays a crucial role in the early detection of HCC, although…”
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[6,6'- 2 H 2 ] fructose as a deuterium metabolic imaging probe in liver cancer by Zhang, Guannan, Cullen, Quinlan, Berishaj, Marjan, Deh, Kofi, Kim, Nathaniel, Keshari, Kayvan R

“…Hepatocellular carcinoma (HCC) is one of the leading causes of cancer-related deaths. Imaging plays a crucial role in the early detection of HCC, although…”
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