Search Results - "Kim, Nam–Soon"
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Burnout Among Public Health Workers During the COVID-19 Pandemic in South Korea
Published in Journal of occupational and environmental medicine (01-03-2023)“…This study aimed to investigate the prevalence of burnout experiences and factors associated with burnout among Korean health care workers during the…”
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Age‐related cholesterol and colorectal cancer progression: Validating squalene epoxidase for high‐risk cases
Published in Aging cell (01-07-2024)“…As people age, the risk and progression of colorectal cancer (CRC), along with cholesterol levels, tend to increase. Nevertheless, epidemiological studies on…”
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A liver‐specific gene expression panel predicts the differentiation status of in vitro hepatocyte models
Published in Hepatology (Baltimore, Md.) (01-11-2017)“…Alternative cell sources, such as three‐dimensional organoids and induced pluripotent stem cell–derived cells, might provide a potentially effective approach…”
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Autosomal dominant transmission of complicated hereditary spastic paraplegia due to a dominant negative mutation of KIF1A, SPG30 gene
Published in Scientific reports (02-10-2017)“…KIF1A is a brain-specific anterograde motor protein that transports cargoes towards the plus-ends of microtubules. Many variants of the KIF1A gene have been…”
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Phosphorylation of FOXP3 by LCK downregulates MMP9 expression and represses cell invasion
Published in PloS one (14-10-2013)“…Forkhead Box P3 (FOXP3) is a member of the forkhead/winged helix family of the transcription factors and plays an important role not only as a master gene in…”
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Targeting KRAS Oncogene in Colon Cancer Cells with 7-Carboxylate Indolo[3,2-b]quinoline Tri-Alkylamine Derivatives
Published in PloS one (29-05-2015)“…A guanine-rich strand within the promoter of the KRAS gene can fold into an intra-molecular G-quadruplex structure (G4), which has an important role in the…”
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Nanoplasmonic immunosensor for the detection of SCG2, a candidate serum biomarker for the early diagnosis of neurodevelopmental disorder
Published in Scientific reports (23-11-2021)“…The neural circuits of the infant brain are rapidly established near 6 months of age, but neurodevelopmental disorders can be diagnosed only at the age of…”
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Maternal nanoplastic ingestion induces an increase in offspring body weight through altered lipid species and microbiota
Published in Environment international (01-03-2024)“…[Display omitted] •Maternal ingestion of NPs increase the body weight of progeny by the elevation of fat mass.•Maternal administration of NPs alters the lipid…”
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The positive correlation of TIPRL with LC3 and CD133 contributes to cancer aggressiveness: potential biomarkers for early liver cancer
Published in Scientific reports (14-11-2019)“…Studies have reported dysregulation of TIPRL, LC3 and CD133 in liver cancer tissues. However, their respective relationships to liver cancer and roles as…”
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Spastin Contributes to Neural Development through the Regulation of Microtubule Dynamics in the Primary Cilia of Neural Stem Cells
Published in Neuroscience (15-07-2019)“…Spastin is a microtubule-severing enzyme encoded by SPAST, which is broadly expressed in various cell types originated from multiple organs. Even though SPAST…”
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KRAS oncogene repression in colon cancer cell lines by G-quadruplex binding indolo[3,2-c]quinolines
Published in Scientific reports (08-04-2015)“…KRAS is one of the most frequently mutated oncogenes in human cancer, yet remaining undruggable. To explore a new therapeutic strategy, a library of…”
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Discovery of ALK-PTPN3 gene fusion from human non-small cell lung carcinoma cell line using next generation RNA sequencing
Published in Genes chromosomes & cancer (01-06-2012)“…An increasing number of chromosomal aberrations is being identified in solid tumors providing novel biomarkers for various types of cancer and new insights…”
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Weight control behaviors according to body weight status and accuracy of weight perceptions among Korean women: a nationwide population-based survey
Published in Scientific reports (24-06-2019)“…This study aimed to identify associations among self-perceived weight status, accuracy of weight perceptions, and weight control behaviors, including both…”
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Depression-like behaviors induced by defective PTPRT activity through dysregulated synaptic functions and neurogenesis
Published in Journal of cell science (21-10-2020)“…PTPRT has been known to regulate synaptic formation and dendritic arborization of hippocampal neurons. null and -D401A mutant mice displayed enhanced…”
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Type 1 Sialidosis Patient With a Novel Deletion Mutation in the NEU1 Gene: Case Report and Literature Review
Published in Cerebellum (London, England) (01-06-2019)“…Recent advances in next-generation sequencing technologies have uncovered the genetic backgrounds of various diseases. Type 1 sialidosis (OMIM#256550) is a…”
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FBXL17/spastin axis as a novel therapeutic target of hereditary spastic paraplegia
Published in Cell & bioscience (22-07-2022)“…Abstract Background Spastin significantly influences microtubule regulation in neurons and is implicated in the pathogenesis of hereditary spastic paraplegia…”
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TIPRL potentiates survival of lung cancer by inducing autophagy through the eIF2α-ATF4 pathway
Published in Cell death & disease (20-12-2019)“…Autophagy, an intracellular system of degrading damaged organelles and misfolded proteins, is essential for cancer cell survival. Despite the progress made…”
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Clinical characteristics of ataxia-telangiectasia presenting dystonia as a main manifestation
Published in Clinical neurology and neurosurgery (01-12-2020)“…•A–T should be considered in undiagnosed dystonia, even without typical phenotype of A–T.•Generalized dystonia from childhood or adolescence is characteristic…”
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Inhibition of MKK7–JNK by the TOR Signaling Pathway Regulator-Like Protein Contributes to Resistance of HCC Cells to TRAIL-Induced Apoptosis
Published in Gastroenterology (New York, N.Y. 1943) (01-11-2012)“…Background & Aims The TOR signaling pathway regulator-like (TIPRL) protein, the mammalian ortholog of yeast TIP41, was identified in an expression profiling…”
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