Search Results - "Kim, Nak Doo"

Increased Ubiquitination of Multidrug Resistance 1 by Ginsenoside Rd by Pokharel, Yuba Raj, Kim, Nak Doo, Han, Hyo-Kyung, Oh, Won Keun, Kang, Keon Wook

“…MCF-7/ADR cells, a doxorubicin-resistant human breast cancer cell line, acquires resistance to several chemotherapeutic agents, such as anthracylines and…”
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Ginsenoside Rg3 increases nitric oxide production via increases in phosphorylation and expression of endothelial nitric oxide synthase: Essential roles of estrogen receptor-dependent PI3-kinase and AMP-activated protein kinase by Hien, Tran Thi, Kim, Nak Doo, Pokharel, Yuba Raj, Oh, Seok Jeong, Lee, Moo Yeol, Kang, Keon Wook

“…We previously showed that ginsenosides increase nitric oxide (NO) production in vascular endothelium and that ginsenoside Rg3 (Rg3) is the most active one…”
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Steaming of Ginseng at High Temperature Enhances Biological Activity by Kim, Wang Yu, Kim, Jong Moon, Han, Sang Beom, Lee, Seung Ki, Kim, Nak Doo, Park, Man Ki, Kim, Chong Kook, Park, Jeong Hill

“…The present study was performed to evaluate the effect of steaming ginseng at a temperature over 100 °C on its chemical constituents and biological activities…”
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Ginsenoside Rg3 inhibits phenylephrine‐induced vascular contraction through induction of nitric oxide synthase by Kim, Nak Doo, Kim, Eun Mi, Kang, Keon Wook, Cho, Min Kyung, Choi, So Yeon, Kim, Sang Geon

“…Ginsenoside Rg3 (Rg3) isolated from Panax ginseng relaxes vessels and exerts a cytoprotective effect. In view of the fact that nitric oxide (NO) is involved in…”
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Procyanidins in crataegus extract evoke endothelium-dependent vasorelaxation in rat aorta by Kim, Soon Hoe, Kang, Keon Wook, Kim, Kye Won, Kim, Nak Doo

“…The extract of Crataegus, a mixture of flavonoids and procyanidins extracted from hawthorn, Crataegus oxyacantha, L. and C. monogyna Jacq., relaxed vascular…”
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Synthesis of 2-(Allylthio)pyrazines As a Novel Cancer Chemopreventive Agent by Lee, Jong-Wook, Lee, Bong-yong, Kim, Nak-Doo

“…2-(Allylthio)pyrazine derivatives were designed as a novel cancer chemopreventive agent that functions through selective inhibtion of cytochrome P-450 and…”
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chemopreventive Effects of 2-(Allylthio) pyrazine by Kim, Nak-Doo, Kim, Sang-Geon

“…A series of organosulfur compounds were synthesized with the aim of developing chemopreventive compounds active against hepatotoxicity and chemical…”
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Ginsenoside Rg3 mediates endothelium-dependent relaxation in response to ginsenosides in rat aorta : role of K+ channels by Kim, N D, Kang, S Y, Park, J H, Schini-Kerth, V B

“…The aim of the present study was to characterize the endothelium-dependent relaxation elicited by ginsenosides, a mixture of saponin extracted from Panax…”
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Inhibition of cytochrome P450 2E1 expression by 2-(allylthio)Pyrazine, a Potential chemoprotective agent: hepatoprotective Effects by Kim, Nak Doo, Kwak, Mi Kyong, Kim, Sang Geon

“…Cytochrome P450 2E1 (P450 2E1) is active in both the detoxification and activation of small organic molecules. The effects of 2-(allylthio)pyrazine (2-AP) on…”
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Inhibition of lipopolysaccharide-induced inducible nitric oxide synthase expression by a novel compound, mercaptopyrazine, through suppression of nuclear factor-kappaB binding to DNA by Lim, Sunny, Kang, Keon Wook, Park, Soo-Young, Kim, Seok-In, Choi, Yon Sik, Kim, Nak-Doo, Lee, Ki-Up, Lee, Hong-Kyu, Pak, Youngmi Kim

“…Macrophage cells in response to cytokines and endotoxins produced a large amount of nitric oxide (NO) by expression of inducible nitric oxide synthase (iNOS),…”
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Ginsenosides of the protopanaxatriol group cause endothelium-dependent relaxation in the rat aorta by Kang, S Y, Schini-Kerth, V B, Kim, N D

“…The vasoactive effects of several ginsenosides, purified from Panax ginseng, were tested in the rat aorta. Ginsenosides from the protopanaxatriol group and its…”
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Sex-related Differences in Rat Hepatic Cytochromes P450 Expression Following Treatment with Phenobarbital or 3-Methylcholanthrene by Lee, Yoon-Sook, Park, Sang-Shin, Kim, Nak-Doo

“…The induction of hepatic cytochromes P450 and metabolic effects have been examined in male and female Sprague-Dawley rats following treatment with either…”
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Induction of hepatic inducible nitric oxide synthase by cholesterol in vivo and in vitro by Kim, Jun-Woo, Kang, Keon-Wook, Oh, Goo Taeg, Song, Jihyun, Kim, Nak-Doo, Pak, Youngmi Kim

“…Cholesterol-rich diet impairs endothelial NO synthase (eNOS) and enhances inducible NOS (iNOS) expression. In this study, we investigated effects of…”
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Inhibition of stress-induced plasma corticosterone levels by ginsenosides in mice: involvement of nitric oxide by Kim, Do Hoon, Jung, Jun Sub, Suh, Hong Won, Huh, Sung Oh, Min, Sung-Kil, Son, Bong Ki, Park, Jung Hill, Kim, Nak Doo, Kim, Yung Hi, Song, Dong Keun

“…GINSENG total saponins (GTS) injected intracere-broventricularly (i.c.v.) at doses of 0.1–1 μg inhibited the i.c.v. injection stress-induced plasma…”
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Diethylmaleate and Buthionine Sulfoximine, Glutathione-Depleting Agents, Differentially Inhibit Expression of Inducible Nitric Oxide Synthase in Endotoxemic Mice by Kang, Keon Wook, Pak, Young Mi Kim, Kim, Nak Doo

“…Diethylmaleate (DEM) and buthionine sulfoximine (BSO), glutathione (GSH)-depleting agents, reduced the metabolic activity and the protein level of iNOS in both…”
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α2-Adrenoceptor Antagonists Evoke Endothelium-Dependent and -Independent Relaxations in the Isolated Rat Aorta by Kim, Nak Doo, Kang, Keon Wook, Kang, Soo Yeon, Vanhoutte, Paul M

“…This study was designed to determine whether the α2-adrenoceptor antagonists idazoxan, yohimbine, and rauwolscine cause endothelium-dependent and -independent…”
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Chemopreventive effects of 2-(allylthio)pyrazine on hepatic lesion, mutagenesis and tumorigenesis induced by vinyl carbamate or vinyl carbamate epoxide by SURH, Y.-J, SEONG GON KIM, PARK, K.-K, YEOWON SOHN, LEE, J.-M, NAK DOO KIM, MILLER, J. A

“…2-(Allylthio)pyrazine (2-AP), synthesized for its possible use as a hepatoprotective agent, has been found to selectively inhibit rat hepatic cytochrome P450…”
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Induction of granulocytic differentiation in acute promyelocytic leukemia cells (HL-60) by 2-(allylthio) pyrazine by Kong, Gu, Jeen Lee, Su, Jun Kim, Hyun, Surh, Young-Joon, Doo Kim, Nak

“…Induction of hematopoietic differentiation in human promyelocytic leukemia cells (HL-60) by new synthetic drugs or natural products has recently been…”
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Effect of Ginseng Components on the Potassium Depleted Cardiomyopathic Rats and it's Mechanism of Action by Lee, Jong-Wook, Kim, Nak-Doo

“…The effect of ginseng components on the potassium depleted cardiomyopathic rat heart was investigated. In the perfused heart experiment using Langendorff…”
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2-(Allylthio)pyrazine inhibition of aflatoxin B1-induced hepatocarcinogenesis in rats by Ha, T G, Jang, J J, Kim, S G, Kim, N D

“…2-(Allylthio)pyrazine (2-AP), a synthetic pyrazine derivative with an allylsulfur moiety, has hepatoprotective effects against toxicants. Effect of 2-AP on…”
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